Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00437)
Target Name Histone-lysine N-methyltransferase EZH2 (EZH2)
Synonyms
ENX-1; Enhancer of zeste homolog 2; Lysine N-methyltransferase 6; KMT6
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Gene Name EZH2
Sequence
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP
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Family Class V-like SAM-binding methyltransferase superfamily; Histone-lysine methyltransferase family; EZ subfamily
Function
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Displays a preference for substrates with less methylation, loses activity when progressively more methyl groups are incorporated into H3K27, H3K27me0 > H3K27me1 > H3K27me2. Compared to EZH1-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1, CDKN2A and retinoic acid target genes. EZH2 can also methylate non-histone proteins such as the transcription factor GATA4 and the nuclear receptor RORA. Regulates the circadian clock via histone methylation at the promoter of the circadian genes. Essential for the CRY1/2-mediated repression of the transcriptional activation of PER1/2 by the CLOCK-ARNTL/BMAL1 heterodimer; involved in the di and trimethylation of 'Lys-27' of histone H3 on PER1/2 promoters which is necessary for the CRY1/2 proteins to inhibit transcription.
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Gene ID 2146
HGNC ID HGNC:3527
Ensembl Gene ID ENSG00000106462
KEGG ID hsa:2146
Chromosomal Location 7q36.1
RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00437)
Histone-lysine N-methyltransferase EZH2 (EZH2)
Adenosine-to-Inosine editing (A-to-I)
In total 4 m6A sequence/site(s) in this target gene
mod ID: A2ISITE002392 Click to Show/Hide the Full List
mod site chr7:148811422-148811423:- [1]
Sequence CGCGGTGGCCGACTCCTGCAATCCCAGCACTTTGGGAGGCC
Transcript ID List ENST00000478654.5; ENST00000460911.5; ENST00000476773.5; ENST00000320356.6; rmsk_2406372; ENST00000492143.5; ENST00000469631.1; ENST00000483967.5; ENST00000350995.6
External Link RMBase: RNA-editing_site_127936
mod ID: A2ISITE002393 Click to Show/Hide the Full List
mod site chr7:148828540-148828541:- [2]
Sequence ATCCTAGCACTTGGGAGGCTAAGGTGGGCAGATTGCTTGAG
Transcript ID List ENST00000320356.6; rmsk_2406399; ENST00000492143.5; ENST00000498186.5; ENST00000350995.6; ENST00000460911.5; ENST00000483012.1; ENST00000483967.5; ENST00000476773.5; ENST00000478654.5
External Link RMBase: RNA-editing_site_127937
mod ID: A2ISITE002394 Click to Show/Hide the Full List
mod site chr7:148838939-148838940:- [1]
Sequence TGTGCCTTGGCCTCCAGAGCAGCTGGGACTACAGGCATGCA
Transcript ID List ENST00000478654.5; ENST00000350995.6; ENST00000483012.1; ENST00000492143.5; ENST00000320356.6; ENST00000498186.5; ENST00000460911.5; ENST00000483967.5; ENST00000476773.5
External Link RMBase: RNA-editing_site_127938
mod ID: A2ISITE002395 Click to Show/Hide the Full List
mod site chr7:148869442-148869443:- [3]
Sequence TGAGGTGAGAGGGTCGCTTGAGCCCAGAAGGTAGAGACTGC
Transcript ID List ENST00000492143.5; ENST00000498186.5; ENST00000478654.5; ENST00000476773.5; ENST00000320356.6; ENST00000350995.6; ENST00000460911.5; ENST00000483967.5; ENST00000483012.1; rmsk_2406482
External Link RMBase: RNA-editing_site_127939
2'-O-Methylation (2'-O-Me)
In total 1 m6A sequence/site(s) in this target gene
mod ID: 2OMSITE000472 Click to Show/Hide the Full List
mod site chr7:148812168-148812169:- [4]
Sequence AGAATCAGGGGGTGTCCTGGGGCTGAAAATGGAATAACTAT
Cell/Tissue List HEK293
Seq Type List RiboMeth-seq
Transcript ID List ENST00000350995.6; ENST00000492143.5; ENST00000476773.5; ENST00000320356.6; ENST00000460911.5; ENST00000483967.5; ENST00000478654.5
External Link RMBase: Nm_site_6272
N6-methyladenosine (m6A)
In total 52 m6A sequence/site(s) in this target gene
mod ID: M6ASITE082972 Click to Show/Hide the Full List
mod site chr7:148807410-148807411:- [5]
Sequence GCAGTATGGTACATTTTTCAACTTTGAATAAAGAATACTTG
Motif Score 2.595904762
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000478654.5; ENST00000492143.5; ENST00000320356.6; ENST00000460911.5; ENST00000350995.6
External Link RMBase: m6A_site_781241
mod ID: M6ASITE082973 Click to Show/Hide the Full List
mod site chr7:148807420-148807421:- [6]
Sequence TTGCAATAATGCAGTATGGTACATTTTTCAACTTTGAATAA
Motif Score 2.856142857
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000350995.6; ENST00000320356.6; ENST00000460911.5; ENST00000478654.5; ENST00000492143.5
External Link RMBase: m6A_site_781242
mod ID: M6ASITE082974 Click to Show/Hide the Full List
mod site chr7:148807491-148807492:- [5]
Sequence AGTAATGAGTTTAAAAATCAACTTTTTATTGCCTTCTCACC
Motif Score 2.595904762
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000350995.6; ENST00000460911.5; ENST00000476773.5; ENST00000320356.6; ENST00000492143.5; ENST00000478654.5
External Link RMBase: m6A_site_781243
mod ID: M6ASITE082975 Click to Show/Hide the Full List
mod site chr7:148807561-148807562:- [7]
Sequence GTGGGCAATTTAGAAAAAGAACATGCAGTTTGAAATTCTGA
Motif Score 2.951386905
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000350995.6; ENST00000483967.5; ENST00000478654.5; ENST00000476773.5; ENST00000320356.6; ENST00000492143.5; ENST00000460911.5
External Link RMBase: m6A_site_781244
mod ID: M6ASITE082976 Click to Show/Hide the Full List
mod site chr7:148807593-148807594:- [7]
Sequence CAGCTGCCTTAGCTTCAGGAACCTCGAGTACTGTGGGCAAT
Motif Score 2.930744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000350995.6; ENST00000476773.5; ENST00000320356.6; ENST00000492143.5; ENST00000478654.5; ENST00000483967.5; ENST00000460911.5
External Link RMBase: m6A_site_781245
mod ID: M6ASITE082977 Click to Show/Hide the Full List
mod site chr7:148807614-148807615:- [7]
Sequence CTCCTCCCCCCTCCTCTGAAACAGCTGCCTTAGCTTCAGGA
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000478654.5; ENST00000320356.6; ENST00000460911.5; ENST00000350995.6; ENST00000483967.5; ENST00000492143.5; ENST00000476773.5
External Link RMBase: m6A_site_781246
mod ID: M6ASITE082978 Click to Show/Hide the Full List
mod site chr7:148807645-148807646:- [6]
Sequence AGAGAAATGGAAATCCCTTGACATCTGCTACCTCCTCCCCC
Motif Score 2.859755952
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000350995.6; ENST00000476773.5; ENST00000492143.5; ENST00000320356.6; ENST00000460911.5; ENST00000483967.5; ENST00000478654.5
External Link RMBase: m6A_site_781247
mod ID: M6ASITE082979 Click to Show/Hide the Full List
mod site chr7:148809323-148809324:- [7]
Sequence AAATCATTCGGTAAATCCAAACTGCTATGCAAAAGGTAGGT
Motif Score 2.627720238
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000478654.5; ENST00000492143.5; ENST00000320356.6; ENST00000476773.5; ENST00000460911.5; ENST00000483967.5; ENST00000350995.6
External Link RMBase: m6A_site_781248
mod ID: M6ASITE082980 Click to Show/Hide the Full List
mod site chr7:148809359-148809360:- [6]
Sequence GGATGCAACCCGCAAGGGTAACAAAATTCGTTTTGCAAATC
Motif Score 2.168095238
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000483967.5; ENST00000320356.6; ENST00000478654.5; ENST00000460911.5; ENST00000476773.5; ENST00000492143.5; ENST00000350995.6
External Link RMBase: m6A_site_781249
mod ID: M6ASITE082981 Click to Show/Hide the Full List
mod site chr7:148811634-148811635:- [5]
Sequence AAATGAATTCATCTCAGAATACTGTGGAGAGGTAAGGCACT
Motif Score 2.53247619
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000483967.5; ENST00000460911.5; ENST00000476773.5; ENST00000350995.6; ENST00000320356.6; ENST00000478654.5; ENST00000469631.1; ENST00000492143.5
External Link RMBase: m6A_site_781250
mod ID: M6ASITE082982 Click to Show/Hide the Full List
mod site chr7:148814094-148814095:- [6]
Sequence CCGCTGCAAAGCACAGTGCAACACCAAGCAGTGCCCGTGCT
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000492143.5; ENST00000478654.5; ENST00000483967.5; ENST00000460911.5; ENST00000320356.6; ENST00000476773.5; ENST00000350995.6
External Link RMBase: m6A_site_781251
mod ID: M6ASITE082983 Click to Show/Hide the Full List
mod site chr7:148816688-148816689:- [7]
Sequence CCAAGGAAAAAGAAGAGGAAACACCGGTGAGTCTGTCATGA
Motif Score 2.20572619
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000460911.5; ENST00000478654.5; ENST00000476773.5; ENST00000320356.6; ENST00000492143.5; ENST00000350995.6; ENST00000483967.5
External Link RMBase: m6A_site_781252
mod ID: M6ASITE082984 Click to Show/Hide the Full List
mod site chr7:148816814-148816815:- [7]
Sequence GAATGGTTTGCCTAAATAAGACTGTCCTCATGGCTCTGTGA
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000350995.6; ENST00000476773.5; ENST00000478654.5; ENST00000483967.5; ENST00000492143.5; ENST00000460911.5; ENST00000320356.6
External Link RMBase: m6A_site_781253
mod ID: M6ASITE082985 Click to Show/Hide the Full List
mod site chr7:148817270-148817271:- [5]
Sequence CCTCATTGGCACTTACTATGACAATTTCTGTGCCATTGCTA
Motif Score 2.859755952
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000478654.5; ENST00000350995.6; ENST00000476773.5; ENST00000460911.5; ENST00000492143.5; ENST00000483967.5; ENST00000320356.6
External Link RMBase: m6A_site_781254
mod ID: M6ASITE082986 Click to Show/Hide the Full List
mod site chr7:148817341-148817342:- [7]
Sequence AAGATGAAGCCAAATATTGAACCTCCTGAGAATGTGGAGTG
Motif Score 2.930744048
Cell/Tissue List HeLa; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000478654.5; ENST00000492143.5; ENST00000483967.5; ENST00000320356.6; ENST00000476773.5; ENST00000350995.6; ENST00000460911.5
External Link RMBase: m6A_site_781255
mod ID: M6ASITE082987 Click to Show/Hide the Full List
mod site chr7:148817370-148817371:- [7]
Sequence AAGCAAATTCTCGGTGTCAAACACCAATAAAGATGAAGCCA
Motif Score 2.20572619
Cell/Tissue List HeLa; hESC-HEK293T; Huh7
Seq Type List m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List ENST00000483967.5; ENST00000460911.5; ENST00000320356.6; ENST00000350995.6; ENST00000498186.5; ENST00000476773.5; ENST00000478654.5; ENST00000492143.5
External Link RMBase: m6A_site_781256
mod ID: M6ASITE082988 Click to Show/Hide the Full List
mod site chr7:148817870-148817871:- [7]
Sequence CTTCGAGCTCCTCTGGTAAGACACGTCTAATAACTGGGTTT
Motif Score 2.897386905
Cell/Tissue List HeLa; hNPCs; hESCs; HEK293T; fibroblasts; A549; LCLs; H1299; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000476773.5; ENST00000478654.5; ENST00000492143.5; ENST00000498186.5; ENST00000320356.6; ENST00000350995.6; ENST00000460911.5; ENST00000483967.5
External Link RMBase: m6A_site_781257
mod ID: M6ASITE082989 Click to Show/Hide the Full List
mod site chr7:148817891-148817892:- [7]
Sequence AAGAAGAGAAGAAAGATGAAACTTCGAGCTCCTCTGGTAAG
Motif Score 2.627720238
Cell/Tissue List HeLa; CD34; HEK293T; hNPCs; hESCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; MSC
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000460911.5; ENST00000350995.6; ENST00000476773.5; ENST00000492143.5; ENST00000478654.5; ENST00000483967.5; ENST00000320356.6; ENST00000498186.5
External Link RMBase: m6A_site_781258
mod ID: M6ASITE082990 Click to Show/Hide the Full List
mod site chr7:148817926-148817927:- [7]
Sequence GACTGAAACGGGGGGAGAGAACAATGATAAAGAAGAAGAAG
Motif Score 2.951386905
Cell/Tissue List HeLa; CD34; HEK293T; hESC-HEK293T; hNPCs; hESCs; fibroblasts; A549; LCLs; CD8T; H1299; MM6; Huh7; MSC
Seq Type List m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List ENST00000483967.5; ENST00000478654.5; ENST00000476773.5; ENST00000498186.5; ENST00000350995.6; ENST00000460911.5; ENST00000492143.5; ENST00000320356.6
External Link RMBase: m6A_site_781259
mod ID: M6ASITE082991 Click to Show/Hide the Full List
mod site chr7:148817939-148817940:- [8]
Sequence ATAGGGAAGCAGGGACTGAAACGGGGGGAGAGAACAATGAT
Motif Score 2.179660714
Cell/Tissue List CD8T
Seq Type List m6A-CLIP/IP
Transcript ID List ENST00000476773.5; ENST00000350995.6; ENST00000498186.5; ENST00000492143.5; ENST00000320356.6; ENST00000483967.5; ENST00000460911.5; ENST00000478654.5
External Link RMBase: m6A_site_781260
mod ID: M6ASITE082992 Click to Show/Hide the Full List
mod site chr7:148817945-148817946:- [7]
Sequence ACAGTGATAGGGAAGCAGGGACTGAAACGGGGGGAGAGAAC
Motif Score 4.065041667
Cell/Tissue List HeLa; CD34; HEK293T; hNPCs; hESCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; MSC
Seq Type List m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List ENST00000460911.5; ENST00000320356.6; ENST00000483967.5; ENST00000478654.5; ENST00000350995.6; ENST00000476773.5; ENST00000498186.5; ENST00000492143.5
External Link RMBase: m6A_site_781261
mod ID: M6ASITE082993 Click to Show/Hide the Full List
mod site chr7:148817965-148817966:- [7]
Sequence GCTGGAATCAAAGGATACAGACAGTGATAGGGAAGCAGGGA
Motif Score 2.897386905
Cell/Tissue List HeLa; CD34; HEK293T; hNPCs; hESCs; fibroblasts; A549; LCLs; MT4; H1299; MM6; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000492143.5; ENST00000350995.6; ENST00000460911.5; ENST00000476773.5; ENST00000478654.5; ENST00000483967.5; ENST00000498186.5; ENST00000320356.6
External Link RMBase: m6A_site_781262
mod ID: M6ASITE082994 Click to Show/Hide the Full List
mod site chr7:148818068-148818069:- [7]
Sequence TCACCGCTGAGCGGATAAAGACCCCACCAAAACGTCCAGGA
Motif Score 2.876744048
Cell/Tissue List HeLa; CD34; HEK293T; hNPCs; MT4; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000350995.6; ENST00000320356.6; ENST00000460911.5; ENST00000492143.5; ENST00000478654.5; ENST00000476773.5; ENST00000483012.1; ENST00000483967.5; ENST00000498186.5
External Link RMBase: m6A_site_781263
mod ID: M6ASITE082995 Click to Show/Hide the Full List
mod site chr7:148819008-148819009:- [7]
Sequence TATTGCCTGTTGGATTTTGGACAGAAGATTCATTGAATGGC
Motif Score 3.643047619
Cell/Tissue List HeLa; MT4; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000350995.6; ENST00000320356.6; ENST00000483012.1; ENST00000498186.5; ENST00000483967.5; ENST00000460911.5; ENST00000476773.5; ENST00000492143.5; ENST00000478654.5
External Link RMBase: m6A_site_781264
mod ID: M6ASITE082996 Click to Show/Hide the Full List
mod site chr7:148819042-148819043:- [7]
Sequence CAAGCCACTCCTACCTAGGAACTAAATGGGTATATATTGCC
Motif Score 3.373380952
Cell/Tissue List HeLa; MT4; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000492143.5; ENST00000460911.5; ENST00000320356.6; ENST00000478654.5; ENST00000350995.6; ENST00000476773.5; ENST00000498186.5; ENST00000483967.5; ENST00000483012.1
External Link RMBase: m6A_site_781265
mod ID: M6ASITE082997 Click to Show/Hide the Full List
mod site chr7:148819616-148819617:- [7]
Sequence CTAGACAACAAACCTTGTGGACCACAGTGTTACCAGCATTT
Motif Score 3.622404762
Cell/Tissue List HeLa; MT4; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000483012.1; ENST00000483967.5; ENST00000492143.5; ENST00000350995.6; ENST00000478654.5; ENST00000460911.5; ENST00000498186.5; ENST00000476773.5; ENST00000320356.6
External Link RMBase: m6A_site_781266
mod ID: M6ASITE082998 Click to Show/Hide the Full List
mod site chr7:148819625-148819626:- [7]
Sequence GAAACAGCTCTAGACAACAAACCTTGTGGACCACAGTGTTA
Motif Score 2.185083333
Cell/Tissue List HeLa; MT4; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000460911.5; ENST00000498186.5; ENST00000350995.6; ENST00000320356.6; ENST00000483967.5; ENST00000476773.5; ENST00000492143.5; ENST00000478654.5; ENST00000483012.1
External Link RMBase: m6A_site_781267
mod ID: M6ASITE082999 Click to Show/Hide the Full List
mod site chr7:148819632-148819633:- [7]
Sequence GAACACAGAAACAGCTCTAGACAACAAACCTTGTGGACCAC
Motif Score 2.897386905
Cell/Tissue List HeLa; MT4; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000492143.5; ENST00000498186.5; ENST00000476773.5; ENST00000350995.6; ENST00000483012.1; ENST00000460911.5; ENST00000483967.5; ENST00000320356.6; ENST00000478654.5
External Link RMBase: m6A_site_781268
mod ID: M6ASITE083000 Click to Show/Hide the Full List
mod site chr7:148819642-148819643:- [7]
Sequence ATAAGCGGAAGAACACAGAAACAGCTCTAGACAACAAACCT
Motif Score 2.20572619
Cell/Tissue List HeLa; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000478654.5; ENST00000492143.5; ENST00000476773.5; ENST00000483012.1; ENST00000483967.5; ENST00000498186.5; ENST00000350995.6; ENST00000460911.5; ENST00000320356.6
External Link RMBase: m6A_site_781269
mod ID: M6ASITE083001 Click to Show/Hide the Full List
mod site chr7:148819650-148819651:- [7]
Sequence CAACACTTATAAGCGGAAGAACACAGAAACAGCTCTAGACA
Motif Score 2.951386905
Cell/Tissue List HeLa; CD34; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000460911.5; ENST00000350995.6; ENST00000492143.5; ENST00000320356.6; ENST00000478654.5; ENST00000498186.5; ENST00000483012.1; ENST00000483967.5; ENST00000476773.5
External Link RMBase: m6A_site_781270
mod ID: M6ASITE083002 Click to Show/Hide the Full List
mod site chr7:148826472-148826473:- [6]
Sequence TTTAAATATGACTGCTTCCTACATCGTAAGTGCAATTATTG
Motif Score 2.078666667
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000483967.5; ENST00000320356.6; ENST00000483012.1; ENST00000492143.5; ENST00000460911.5; ENST00000350995.6; ENST00000476773.5; ENST00000478654.5; ENST00000498186.5
External Link RMBase: m6A_site_781271
mod ID: M6ASITE083003 Click to Show/Hide the Full List
mod site chr7:148826526-148826527:- [6]
Sequence GTTCAGAGAGAGCAAAGCTTACACTCCTTTCATACGCTTTT
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000476773.5; ENST00000492143.5; ENST00000483012.1; ENST00000478654.5; ENST00000460911.5; ENST00000498186.5; ENST00000320356.6; ENST00000350995.6; ENST00000483967.5
External Link RMBase: m6A_site_781272
mod ID: M6ASITE083004 Click to Show/Hide the Full List
mod site chr7:148826562-148826563:- [7]
Sequence TGTACCCCCAACATAGATGGACCAAATGCTAAATCTGTTCA
Motif Score 3.622404762
Cell/Tissue List HeLa; CD34; hNPCs; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000483967.5; ENST00000476773.5; ENST00000350995.6; ENST00000492143.5; ENST00000320356.6; ENST00000460911.5; ENST00000478654.5; ENST00000498186.5; ENST00000483012.1
External Link RMBase: m6A_site_781273
mod ID: M6ASITE083005 Click to Show/Hide the Full List
mod site chr7:148826572-148826573:- [6]
Sequence TCCTCCTGAATGTACCCCCAACATAGATGGACCAAATGCTA
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000350995.6; ENST00000476773.5; ENST00000492143.5; ENST00000483967.5; ENST00000483012.1; ENST00000460911.5; ENST00000320356.6; ENST00000478654.5; ENST00000498186.5
External Link RMBase: m6A_site_781274
mod ID: M6ASITE083006 Click to Show/Hide the Full List
mod site chr7:148826613-148826614:- [7]
Sequence AGATATAAAGAACTCACCGAACAGCAGCTCCCAGGCGCACT
Motif Score 2.951386905
Cell/Tissue List HeLa; CD34; hNPCs
Seq Type List m6A-seq
Transcript ID List ENST00000483012.1; ENST00000498186.5; ENST00000460911.5; ENST00000492143.5; ENST00000483967.5; ENST00000320356.6; ENST00000478654.5; ENST00000350995.6; ENST00000476773.5
External Link RMBase: m6A_site_781275
mod ID: M6ASITE083007 Click to Show/Hide the Full List
mod site chr7:148826622-148826623:- [7]
Sequence GTTAATGTCAGATATAAAGAACTCACCGAACAGCAGCTCCC
Motif Score 3.373380952
Cell/Tissue List HeLa; CD34; hNPCs
Seq Type List m6A-seq
Transcript ID List ENST00000476773.5; ENST00000478654.5; ENST00000483012.1; ENST00000460911.5; ENST00000483967.5; ENST00000320356.6; ENST00000498186.5; ENST00000492143.5; ENST00000350995.6
External Link RMBase: m6A_site_781276
mod ID: M6ASITE083008 Click to Show/Hide the Full List
mod site chr7:148827174-148827175:- [7]
Sequence GATAAGGGCACAGCAGAAGAACTAAAGGAAAAGTAAGAATT
Motif Score 3.373380952
Cell/Tissue List HeLa; CD34; hNPCs
Seq Type List m6A-seq
Transcript ID List ENST00000492143.5; ENST00000460911.5; ENST00000483967.5; ENST00000483012.1; ENST00000350995.6; ENST00000476773.5; ENST00000498186.5; ENST00000320356.6; ENST00000478654.5
External Link RMBase: m6A_site_781277
mod ID: M6ASITE083009 Click to Show/Hide the Full List
mod site chr7:148828810-148828811:- [5]
Sequence TGGTCAATATAATGATGATGACGATGATGATGATGGAGACG
Motif Score 2.833690476
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000483012.1; ENST00000478654.5; ENST00000498186.5; ENST00000492143.5; ENST00000483967.5; ENST00000320356.6; ENST00000460911.5; ENST00000476773.5; ENST00000350995.6
External Link RMBase: m6A_site_781278
mod ID: M6ASITE083010 Click to Show/Hide the Full List
mod site chr7:148829740-148829741:- [6]
Sequence AAAAATTATGATGGGAAAGTACACGGGGATAGAGGTGAGCC
Motif Score 2.856142857
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000483967.5; ENST00000483012.1; ENST00000492143.5; ENST00000320356.6; ENST00000476773.5; ENST00000460911.5; ENST00000498186.5; ENST00000478654.5; ENST00000350995.6
External Link RMBase: m6A_site_781279
mod ID: M6ASITE083011 Click to Show/Hide the Full List
mod site chr7:148829767-148829768:- [7]
Sequence GATGGTACTTTCATTGAAGAACTAATAAAAAATTATGATGG
Motif Score 3.373380952
Cell/Tissue List HeLa; CD34; HEK293T
Seq Type List m6A-seq; DART-seq
Transcript ID List ENST00000483967.5; ENST00000492143.5; ENST00000478654.5; ENST00000483012.1; ENST00000498186.5; ENST00000476773.5; ENST00000350995.6; ENST00000460911.5; ENST00000320356.6
External Link RMBase: m6A_site_781280
mod ID: M6ASITE083012 Click to Show/Hide the Full List
mod site chr7:148829822-148829823:- [6]
Sequence AGATGAAACTGTTTTACATAACATTCCTTATATGGGAGATG
Motif Score 2.168095238
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000478654.5; ENST00000483967.5; ENST00000492143.5; ENST00000498186.5; ENST00000476773.5; ENST00000350995.6; ENST00000483012.1; ENST00000320356.6; ENST00000460911.5
External Link RMBase: m6A_site_781281
mod ID: M6ASITE083013 Click to Show/Hide the Full List
mod site chr7:148829835-148829836:- [7]
Sequence TCTTTTAGGTGGAAGATGAAACTGTTTTACATAACATTCCT
Motif Score 2.627720238
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000350995.6; ENST00000476773.5; ENST00000478654.5; ENST00000492143.5; ENST00000460911.5; ENST00000498186.5; ENST00000483012.1; ENST00000483967.5; ENST00000320356.6
External Link RMBase: m6A_site_781282
mod ID: M6ASITE083014 Click to Show/Hide the Full List
mod site chr7:148832719-148832720:- [6]
Sequence CCAGTGACTTGGATTTTCCAACACAAGTCATCCCATTAAAG
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000478654.5; ENST00000483012.1; ENST00000483967.5; ENST00000492143.5; ENST00000320356.6; ENST00000460911.5; ENST00000498186.5; ENST00000350995.6; ENST00000476773.5
External Link RMBase: m6A_site_781283
mod ID: M6ASITE083015 Click to Show/Hide the Full List
mod site chr7:148836945-148836946:- [7]
Sequence TAACACAGTTTTTACTTGGAACCAGCCTTCTGCCAAGAGTC
Motif Score 2.930744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000483012.1; ENST00000478654.5; ENST00000476773.5; ENST00000492143.5; ENST00000350995.6; ENST00000320356.6; ENST00000483967.5; ENST00000460911.5; ENST00000498186.5
External Link RMBase: m6A_site_781284
mod ID: M6ASITE083016 Click to Show/Hide the Full List
mod site chr7:148846509-148846510:- [6]
Sequence GCGAAGGATACAGCCTGTGCACATCCTGACTTCTGTGAGCT
Motif Score 2.830589286
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000483967.5; ENST00000320356.6; ENST00000476773.5; ENST00000483012.1; ENST00000492143.5; ENST00000498186.5; ENST00000478654.5; ENST00000350995.6; ENST00000460911.5
External Link RMBase: m6A_site_781285
mod ID: M6ASITE083017 Click to Show/Hide the Full List
mod site chr7:148847230-148847231:- [6]
Sequence GAAGCGTGTAAAATCAGAGTACATGCGACTGAGACAGCTCA
Motif Score 2.856142857
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000320356.6; ENST00000460911.5; ENST00000476773.5; ENST00000478654.5; ENST00000483967.5; ENST00000492143.5; ENST00000483012.1; ENST00000350995.6; ENST00000498186.5
External Link RMBase: m6A_site_781286
mod ID: M6ASITE083018 Click to Show/Hide the Full List
mod site chr7:148847265-148847266:- [9]
Sequence GGGAAGAAATCTGAGAAGGGACCAGTTTGTTGGCGGAAGCG
Motif Score 3.622404762
Cell/Tissue List MT4; HEK293A-TOA; iSLK; TIME
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000492143.5; ENST00000320356.6; ENST00000460911.5; ENST00000483012.1; ENST00000476773.5; ENST00000478654.5; ENST00000483967.5; ENST00000350995.6; ENST00000498186.5
External Link RMBase: m6A_site_781287
mod ID: M6ASITE083019 Click to Show/Hide the Full List
mod site chr7:148847288-148847289:- [9]
Sequence TTAGAATAATCATGGGCCAGACTGGGAAGAAATCTGAGAAG
Motif Score 3.319380952
Cell/Tissue List MT4; HEK293A-TOA; iSLK; TIME
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000350995.6; ENST00000498186.5; ENST00000483012.1; ENST00000478654.5; ENST00000476773.5; ENST00000483967.5; ENST00000492143.5; ENST00000320356.6; ENST00000460911.5
External Link RMBase: m6A_site_781288
mod ID: M6ASITE083020 Click to Show/Hide the Full List
mod site chr7:148883211-148883212:- [7]
Sequence GAAGCACGATCTTTTGGAAAACTTGGTGAACGCCTAGTGAG
Motif Score 2.627720238
Cell/Tissue List HeLa; MT4; HEK293A-TOA; iSLK; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000460911.5; ENST00000483967.5; ENST00000492143.5; ENST00000478654.5; ENST00000498186.5; ENST00000350995.6; ENST00000483012.1; ENST00000320356.6; ENST00000476773.5
External Link RMBase: m6A_site_781289
mod ID: M6ASITE083021 Click to Show/Hide the Full List
mod site chr7:148884190-148884191:- [6]
Sequence CGCGGGGGCGACGCGCGGGAACAACGCGAGTCGGCGCGCGG
Motif Score 2.951386905
Cell/Tissue List hESC-HEK293T; U2OS; MT4; HEK293A-TOA
Seq Type List MAZTER-seq; MeRIP-seq; m6A-seq
Transcript ID List ENST00000350995.6; ENST00000492143.5; ENST00000483012.1; ENST00000460911.5; ENST00000498186.5; ENST00000320356.6; ENST00000483967.5
External Link RMBase: m6A_site_781290
mod ID: M6ASITE083022 Click to Show/Hide the Full List
mod site chr7:148884251-148884252:- [7]
Sequence CGCGTCCGACACCCGGTGGGACTCAGAAGGCAGTGGAGCCC
Motif Score 4.065041667
Cell/Tissue List HeLa; MT4; HEK293T; HEK293A-TOA
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000320356.6; ENST00000498186.5; ENST00000483967.5; ENST00000483012.1; ENST00000492143.5
External Link RMBase: m6A_site_781291
mod ID: M6ASITE083023 Click to Show/Hide the Full List
mod site chr7:148884263-148884264:- [6]
Sequence GCTCGGTCCGGTCGCGTCCGACACCCGGTGGGACTCAGAAG
Motif Score 2.865571429
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000498186.5; ENST00000320356.6; ENST00000483012.1; ENST00000492143.5; ENST00000483967.5
External Link RMBase: m6A_site_781292