Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00309)
Target Name Dual specificity protein phosphatase 2 (DUSP2)
Synonyms
Dual specificity protein phosphatase PAC-1; PAC1
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Gene Name DUSP2
Sequence
MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPVPWNALLRRRARGPPAAVLACLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
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Family Protein-tyrosine phosphatase family; Non-receptor class dual specificity subfamily
Function
Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
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Gene ID 1844
HGNC ID HGNC:3068
Ensembl Gene ID ENSG00000158050
KEGG ID hsa:1844
Chromosomal Location 2q11.2
RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00309)
Dual specificity protein phosphatase 2 (DUSP2)
5-methylcytidine (m5C)
In total 4 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002379 Click to Show/Hide the Full List
mod site chr2:96143688-96143689:- [1]
Sequence CTCAGAGTTTCAGAAGCCCCCACATGGGGGCTCTAGGAATG
Seq Type List Bisulfite-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m5C_site_26881
mod ID: M5CSITE002380 Click to Show/Hide the Full List
mod site chr2:96143689-96143690:- [1]
Sequence CCTCAGAGTTTCAGAAGCCCCCACATGGGGGCTCTAGGAAT
Seq Type List Bisulfite-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m5C_site_26882
mod ID: M5CSITE002381 Click to Show/Hide the Full List
mod site chr2:96143690-96143691:- [1]
Sequence TCCTCAGAGTTTCAGAAGCCCCCACATGGGGGCTCTAGGAA
Seq Type List Bisulfite-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m5C_site_26883
mod ID: M5CSITE002382 Click to Show/Hide the Full List
mod site chr2:96143691-96143692:- [1]
Sequence CTCCTCAGAGTTTCAGAAGCCCCCACATGGGGGCTCTAGGA
Seq Type List Bisulfite-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m5C_site_26884
N6-methyladenosine (m6A)
In total 13 m6A sequence/site(s) in this target gene
mod ID: M6ASITE046232 Click to Show/Hide the Full List
mod site chr2:96143384-96143385:- [2]
Sequence TGTTCCTGGGGAAGCTGGGGACTTGGGAAGTGATGGGTGTG
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m6A_site_483812
mod ID: M6ASITE046233 Click to Show/Hide the Full List
mod site chr2:96143471-96143472:- [2]
Sequence CAGCCTGAGAGCTCCAAGGAACAAGCTGTGACAACCAGGAG
Motif Score 2.951386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m6A_site_483813
mod ID: M6ASITE046234 Click to Show/Hide the Full List
mod site chr2:96143594-96143595:- [2]
Sequence GCCCTCATTCGGGGTCGGGAACCAAGGGTGTGTCTGCTCTT
Motif Score 2.930744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m6A_site_483814
mod ID: M6ASITE046235 Click to Show/Hide the Full List
mod site chr2:96143624-96143625:- [2]
Sequence TGGTGCTCTTCTGCTGGGGGACTGAGGCTGGCCCTCATTCG
Motif Score 4.065041667
Cell/Tissue List HeLa; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m6A_site_483815
mod ID: M6ASITE046236 Click to Show/Hide the Full List
mod site chr2:96143768-96143769:- [2]
Sequence CTGGCAGGAGCTGACTGTGGACTGGTGGGCTCCCCTCTGGG
Motif Score 4.065041667
Cell/Tissue List HeLa; H1A; H1B; GM12878; CD8T; HEK293A-TOA; endometrial
Seq Type List m6A-seq; m6A-CLIP/IP
Transcript ID List ENST00000488952.1; ENST00000288943.5
External Link RMBase: m6A_site_483816
mod ID: M6ASITE046237 Click to Show/Hide the Full List
mod site chr2:96143842-96143843:- [2]
Sequence GGCAGCTGCTGCAGTTTGAGACCCAGGTGCTGTGTCACTGA
Motif Score 2.876744048
Cell/Tissue List HeLa; GM12878; HEK293A-TOA; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000488952.1; ENST00000288943.5
External Link RMBase: m6A_site_483817
mod ID: M6ASITE046238 Click to Show/Hide the Full List
mod site chr2:96144024-96144025:- [2]
Sequence CCTTGCAGACTGGGTGAAGAACAGCGGAGGCCGGGTGCTGG
Motif Score 2.951386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000488952.1; ENST00000288943.5
External Link RMBase: m6A_site_483818
mod ID: M6ASITE046239 Click to Show/Hide the Full List
mod site chr2:96144484-96144485:- [2]
Sequence ACCTGTCTCAGGTCAGGAGGACTGGCTGAGGAGTCCTCTTG
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000488952.1; ENST00000288943.5
External Link RMBase: m6A_site_483819
mod ID: M6ASITE046241 Click to Show/Hide the Full List
mod site chr2:96144798-96144799:- [2]
Sequence TGCCGCCAACAGGGGACAAAACCAGCCGCTCCGACTCCAGG
Motif Score 2.185083333
Cell/Tissue List HeLa; MT4; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m6A_site_483820
mod ID: M6ASITE046242 Click to Show/Hide the Full List
mod site chr2:96144803-96144804:- [2]
Sequence TGCGCTGCCGCCAACAGGGGACAAAACCAGCCGCTCCGACT
Motif Score 3.643047619
Cell/Tissue List HeLa; MT4; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m6A_site_483821
mod ID: M6ASITE046243 Click to Show/Hide the Full List
mod site chr2:96145002-96145003:- [2]
Sequence TGGCCGCGCTGCTGCACGAGACCCGCGCGGGGCCCACTGCC
Motif Score 2.876744048
Cell/Tissue List HeLa; MT4; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m6A_site_483822
mod ID: M6ASITE046244 Click to Show/Hide the Full List
mod site chr2:96145262-96145263:- [3]
Sequence GGAACGCACGCTGCTGCTGGACTGCCGCCCCTTCCTGGCCT
Motif Score 4.065041667
Cell/Tissue List HeLa; Jurkat; CD4T; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m6A_site_483823
mod ID: M6ASITE046245 Click to Show/Hide the Full List
mod site chr2:96145385-96145386:- [2]
Sequence GAGCCCGGGACGCGGGAAAGACCGAAAGGAAGAGGAAGAGG
Motif Score 2.876744048
Cell/Tissue List HeLa; H1A; MT4; Jurkat; CD4T; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000288943.5
External Link RMBase: m6A_site_483824