Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00261)

Target Name	Heterogeneous nuclear ribonucleoprotein M (HNRNPM)
Synonyms	HTGR1; HNRNPM4; HNRPM4; CEAR; NAGR1; HNRPM Click to Show/Hide
Gene Name	HNRNPM
Sequence	MAAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGPKGEGERPAQNEKRKEKNIKRGGNRFEPYANPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIERMGPLGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMERMVPAGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGGGGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA Click to Show/Hide
Function	Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. Click to Show/Hide
Gene ID	4670
HGNC ID	HGNC:5046
Ensembl Gene ID	ENSG00000099783
KEGG ID	hsa:4670
Chromosomal Location	19p13.2

RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00261)

Heterogeneous nuclear ribonucleoprotein M (HNRNPM)

Adenosine-to-Inosine editing (A-to-I)

In total 2 m6A sequence/site(s) in this target gene
mod ID: A2ISITE008936		Click to Show/Hide the Full List
mod site	chr19:8473900-8473901:+		[1]
Sequence	TTCTGGCTGTCTCACTAACTAGCTCTGTGACCTTGGGCAGA
Transcript ID List	ENST00000620401.4; ENST00000594907.5; ENST00000348943.7; ENST00000325495.9; ENST00000600806.5; ENST00000600092.5; rmsk_4931127; ENST00000597270.1; ENST00000598367.5
External Link	RMBase: RNA-editing_site_65532
mod ID: A2ISITE008937		Click to Show/Hide the Full List
mod site	chr19:8477475-8477476:+		[1]
Sequence	AAGACCAGCCAGGGCAACATAGTGAGACCTCCTCTCTACAA
Transcript ID List	ENST00000348943.7; ENST00000600806.5; rmsk_4931133; ENST00000597270.1; ENST00000325495.9; ENST00000620401.4; ENST00000600092.5; ENST00000594907.5
External Link	RMBase: RNA-editing_site_65533

5-methylcytidine (m5C)

In total 7 m6A sequence/site(s) in this target gene
mod ID: M5CSITE001731		Click to Show/Hide the Full List
mod site	chr19:8485593-8485594:+		[2]
Sequence	CCCACCTGTGTTTTGTGTCCCTGTTTCAGGTGGAGGTGGAG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000597081.1; ENST00000600092.5; ENST00000594907.5; ENST00000325495.9; ENST00000620401.4; ENST00000598603.1; ENST00000600806.5; ENST00000597270.1; ENST00000348943.7
External Link	RMBase: m5C_site_22462
mod ID: M5CSITE001732		Click to Show/Hide the Full List
mod site	chr19:8486206-8486207:+		[3]
Sequence	AACAGCCTCGAGCGCATGGGCCCTGCCATGGGCCCGGCCCT
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000600806.5; ENST00000597270.1; ENST00000325495.9; ENST00000598999.1; ENST00000620401.4; ENST00000596295.1; ENST00000348943.7; ENST00000597081.1
External Link	RMBase: m5C_site_22463
mod ID: M5CSITE001733		Click to Show/Hide the Full List
mod site	chr19:8486207-8486208:+		[2]
Sequence	ACAGCCTCGAGCGCATGGGCCCTGCCATGGGCCCGGCCCTG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000598999.1; ENST00000600806.5; ENST00000620401.4; ENST00000597270.1; ENST00000348943.7; ENST00000325495.9; ENST00000596295.1; ENST00000597081.1
External Link	RMBase: m5C_site_22464
mod ID: M5CSITE001734		Click to Show/Hide the Full List
mod site	chr19:8486208-8486209:+		[3]
Sequence	CAGCCTCGAGCGCATGGGCCCTGCCATGGGCCCGGCCCTGG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000600806.5; ENST00000597270.1; ENST00000598999.1; ENST00000597081.1; ENST00000348943.7; ENST00000620401.4; ENST00000596295.1; ENST00000325495.9
External Link	RMBase: m5C_site_22465
mod ID: M5CSITE001735		Click to Show/Hide the Full List
mod site	chr19:8486218-8486219:+		[3]
Sequence	CGCATGGGCCCTGCCATGGGCCCGGCCCTGGGCGCTGGCAT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000596295.1; ENST00000598999.1; ENST00000597081.1; ENST00000348943.7; ENST00000600806.5; ENST00000597270.1; ENST00000620401.4; ENST00000325495.9
External Link	RMBase: m5C_site_22466
mod ID: M5CSITE001736		Click to Show/Hide the Full List
mod site	chr19:8486219-8486220:+		[3]
Sequence	GCATGGGCCCTGCCATGGGCCCGGCCCTGGGCGCTGGCATT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000600806.5; ENST00000597270.1; ENST00000348943.7; ENST00000598999.1; ENST00000620401.4; ENST00000597081.1; ENST00000596295.1; ENST00000325495.9
External Link	RMBase: m5C_site_22467
mod ID: M5CSITE001737		Click to Show/Hide the Full List
mod site	chr19:8486220-8486221:+		[3]
Sequence	CATGGGCCCTGCCATGGGCCCGGCCCTGGGCGCTGGCATTG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000620401.4; ENST00000325495.9; ENST00000597270.1; ENST00000598999.1; ENST00000348943.7; ENST00000600806.5; ENST00000596295.1; ENST00000597081.1
External Link	RMBase: m5C_site_22468

N6-methyladenosine (m6A)

In total 46 m6A sequence/site(s) in this target gene
mod ID: M6ASITE039242		Click to Show/Hide the Full List
mod site	chr19:8444974-8444975:+		[4]
Sequence	GCGGTGCAGCCCGTTCGCTCACACAAAGCCCAGACGCGGAG
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000597813.5; ENST00000325495.9; ENST00000348943.7; ENST00000600092.5
External Link	RMBase: m6A_site_416292
mod ID: M6ASITE039243		Click to Show/Hide the Full List
mod site	chr19:8455448-8455449:+		[5]
Sequence	TGAGAAGAGGAAGGAGAAAAACATAAAAAGAGGAGGCAATC
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34; HepG2; A549; hESC-HEK293T; BGC823; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000600092.5; ENST00000348943.7; ENST00000600806.5; ENST00000596984.5; ENST00000594907.5; ENST00000597813.5; ENST00000620401.4; ENST00000601645.5; ENST00000325495.9
External Link	RMBase: m6A_site_416299
mod ID: M6ASITE039245		Click to Show/Hide the Full List
mod site	chr19:8455520-8455521:+		[5]
Sequence	ATACAGAGCCTTCATTACAAACATACCTTTTGATGTGAAAT
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34; HepG2; A549; hESC-HEK293T; BGC823; U2OS; hNPCs; fibroblasts; H1299; Huh7; peripheral-blood; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000601645.5; ENST00000600806.5; ENST00000325495.9; ENST00000594907.5; ENST00000596984.5; ENST00000600092.5; ENST00000348943.7; ENST00000597813.5; ENST00000620401.4
External Link	RMBase: m6A_site_416300
mod ID: M6ASITE039246		Click to Show/Hide the Full List
mod site	chr19:8455556-8455557:+		[5]
Sequence	GAAATGGCAGTCACTTAAAGACCTGGTTAAAGAAAAAGGTA
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; A549; BGC823; U2OS; hNPCs; HEK293T; fibroblasts; H1299; Huh7; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000597813.5; ENST00000601645.5; ENST00000325495.9; ENST00000596984.5; ENST00000348943.7; ENST00000600092.5; ENST00000594907.5; ENST00000600806.5; ENST00000620401.4
External Link	RMBase: m6A_site_416301
mod ID: M6ASITE039247		Click to Show/Hide the Full List
mod site	chr19:8461975-8461976:+		[5]
Sequence	GGCAGCGATAACAGCATTAAACCAAGCTCAGGGCCCCTGAG
Motif Score	2.185083333
Cell/Tissue List	HeLa; CD34; A549; BGC823; U2OS; hNPCs; H1299; Huh7; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000620401.4; ENST00000597813.5; ENST00000596984.5; ENST00000600092.5; ENST00000601645.5; ENST00000594907.5; ENST00000593293.1; ENST00000325495.9; ENST00000600806.5; ENST00000348943.7
External Link	RMBase: m6A_site_416302
mod ID: M6ASITE039248		Click to Show/Hide the Full List
mod site	chr19:8462516-8462517:+		[5]
Sequence	GGTTTATGTGTCGTCTGGAAACTGATTTGTAGTTGGTGAGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; CD34; BGC823; HepG2; HEK293T; fibroblasts; H1299
Seq Type List	m6A-seq
Transcript ID List	ENST00000620401.4; ENST00000597813.5; ENST00000600806.5; ENST00000594907.5; ENST00000601645.5; ENST00000600092.5; ENST00000593293.1; ENST00000596984.5; ENST00000325495.9; ENST00000348943.7
External Link	RMBase: m6A_site_416303
mod ID: M6ASITE039249		Click to Show/Hide the Full List
mod site	chr19:8462539-8462540:+		[4]
Sequence	GATTTGTAGTTGGTGAGGTAACATACGTGGAGCTCTTAATG
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000600092.5; ENST00000597813.5; ENST00000348943.7; ENST00000600806.5; ENST00000596984.5; ENST00000601645.5; ENST00000593293.1; ENST00000325495.9; ENST00000594907.5; ENST00000620401.4
External Link	RMBase: m6A_site_416304
mod ID: M6ASITE039250		Click to Show/Hide the Full List
mod site	chr19:8462543-8462544:+		[6]
Sequence	TGTAGTTGGTGAGGTAACATACGTGGAGCTCTTAATGGACG
Motif Score	2.084416667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000593293.1; ENST00000601645.5; ENST00000325495.9; ENST00000600092.5; ENST00000594907.5; ENST00000596984.5; ENST00000620401.4; ENST00000348943.7; ENST00000597813.5; ENST00000600806.5
External Link	RMBase: m6A_site_416305
mod ID: M6ASITE039251		Click to Show/Hide the Full List
mod site	chr19:8463645-8463646:+		[5]
Sequence	AAAAGCTGCGGAAGTCCTAAACAAGCATAGTCTGAGCGGAA
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34; hESC-HEK293T; BGC823; HepG2; hNPCs; fibroblasts; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; endometrial
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000600806.5; ENST00000348943.7; ENST00000620401.4; ENST00000593293.1; ENST00000594907.5; ENST00000601645.5; ENST00000597813.5; ENST00000600092.5; ENST00000325495.9; ENST00000598367.5; ENST00000596984.5
External Link	RMBase: m6A_site_416306
mod ID: M6ASITE039252		Click to Show/Hide the Full List
mod site	chr19:8463667-8463668:+		[5]
Sequence	AAGCATAGTCTGAGCGGAAGACCACTGAAAGTCAAAGAAGT
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; BGC823; HepG2; hNPCs; HEK293T; fibroblasts; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000601645.5; ENST00000598367.5; ENST00000600092.5; ENST00000325495.9; ENST00000593293.1; ENST00000620401.4; ENST00000594907.5; ENST00000348943.7; ENST00000597813.5; ENST00000596984.5; ENST00000600806.5
External Link	RMBase: m6A_site_416307
mod ID: M6ASITE039253		Click to Show/Hide the Full List
mod site	chr19:8465337-8465338:+		[4]
Sequence	TTTTAGGATCCTGATGGTGAACATGCCAGGAGAGCAATGCA
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T; hNPCs; fibroblasts; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; endometrial; NB4
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	ENST00000600806.5; ENST00000600092.5; ENST00000598367.5; ENST00000596984.5; ENST00000620401.4; ENST00000601645.5; ENST00000325495.9; ENST00000594907.5; ENST00000348943.7; ENST00000593293.1
External Link	RMBase: m6A_site_416308
mod ID: M6ASITE039254		Click to Show/Hide the Full List
mod site	chr19:8465394-8465395:+		[7]
Sequence	ACTGGTGGGATGGGTATGGGACCAGGTGGCCCAGGAATGAT
Motif Score	3.622404762
Cell/Tissue List	hNPCs; HEK293T; fibroblasts; H1299; MM6; Jurkat; CD4T; peripheral-blood; endometrial; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000325495.9; ENST00000348943.7; ENST00000600806.5; ENST00000600092.5; ENST00000620401.4; ENST00000598367.5; ENST00000596984.5; ENST00000601645.5; ENST00000594907.5
External Link	RMBase: m6A_site_416309
mod ID: M6ASITE039255		Click to Show/Hide the Full List
mod site	chr19:8465447-8465448:+		[6]
Sequence	CAGTATCCTAAATAATCCCAACATCCCAAATGAGATTATCC
Motif Score	2.173910714
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000325495.9; ENST00000600092.5; ENST00000598367.5; ENST00000620401.4; ENST00000594907.5; ENST00000600806.5; ENST00000596984.5; ENST00000348943.7; ENST00000601645.5
External Link	RMBase: m6A_site_416310
mod ID: M6ASITE039256		Click to Show/Hide the Full List
mod site	chr19:8465475-8465476:+		[8]
Sequence	AATGAGATTATCCATGCATTACAGGCTGGAAGACTTGGAAG
Motif Score	2.07285119
Cell/Tissue List	brain; liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000600806.5; ENST00000596984.5; ENST00000594907.5; ENST00000600092.5; ENST00000348943.7; ENST00000325495.9; ENST00000620401.4; ENST00000601645.5; ENST00000598367.5
External Link	RMBase: m6A_site_416311
mod ID: M6ASITE039257		Click to Show/Hide the Full List
mod site	chr19:8465487-8465488:+		[5]
Sequence	CATGCATTACAGGCTGGAAGACTTGGAAGCACAGTATTTGT
Motif Score	3.319380952
Cell/Tissue List	HeLa; HEK293T; hNPCs; H1299; endometrial
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000594907.5; ENST00000596984.5; ENST00000600092.5; ENST00000600806.5; ENST00000601645.5; ENST00000325495.9; ENST00000620401.4; ENST00000598367.5; ENST00000348943.7
External Link	RMBase: m6A_site_416312
mod ID: M6ASITE039258		Click to Show/Hide the Full List
mod site	chr19:8465497-8465498:+		[8]
Sequence	AGGCTGGAAGACTTGGAAGCACAGTATTTGTAGCAAATGTA
Motif Score	2.830589286
Cell/Tissue List	liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000600806.5; ENST00000348943.7; ENST00000620401.4; ENST00000601645.5; ENST00000598367.5; ENST00000594907.5; ENST00000600092.5; ENST00000325495.9; ENST00000596984.5
External Link	RMBase: m6A_site_416313
mod ID: M6ASITE039259		Click to Show/Hide the Full List
mod site	chr19:8466260-8466261:+		[5]
Sequence	TATAAAGTTGGCTGGAAGAAACTGAAGGAAGTATTTAGTAT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T; hNPCs; H1299
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000325495.9; ENST00000600092.5; ENST00000620401.4; ENST00000601645.5; ENST00000594907.5; ENST00000597270.1; ENST00000600806.5; ENST00000596984.5; ENST00000348943.7; ENST00000598367.5
External Link	RMBase: m6A_site_416314
mod ID: M6ASITE039260		Click to Show/Hide the Full List
mod site	chr19:8466304-8466305:+		[5]
Sequence	TGGTGTGGTGGTCCGAGCAGACATTCTTGAAGATAAAGATG
Motif Score	2.897386905
Cell/Tissue List	HeLa; brain; HEK293; kidney; liver; HEK293T; hESC-HEK293T; hNPCs; H1299
Seq Type List	m6A-seq; m6A-REF-seq; DART-seq; MAZTER-seq
Transcript ID List	ENST00000594907.5; ENST00000597270.1; ENST00000601645.5; ENST00000620401.4; ENST00000600092.5; ENST00000596984.5; ENST00000598367.5; ENST00000325495.9; ENST00000600806.5; ENST00000348943.7
External Link	RMBase: m6A_site_416315
mod ID: M6ASITE039261		Click to Show/Hide the Full List
mod site	chr19:8466359-8466360:+		[5]
Sequence	ATAGGCACTGTTACTTTTGAACAGTCCATTGAAGCTGTGCA
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293; hESC-HEK293T
Seq Type List	m6A-seq; m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000601645.5; ENST00000597270.1; ENST00000596984.5; ENST00000600092.5; ENST00000594907.5; ENST00000325495.9; ENST00000620401.4; ENST00000600806.5; ENST00000348943.7; ENST00000598367.5
External Link	RMBase: m6A_site_416316
mod ID: M6ASITE039262		Click to Show/Hide the Full List
mod site	chr19:8467573-8467574:+		[6]
Sequence	GCTATTTGATAGACCAATGCACGTCAAGATGGTAAGTCAGT
Motif Score	2.80452381
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000597270.1; ENST00000620401.4; ENST00000600806.5; ENST00000601645.5; ENST00000348943.7; ENST00000596984.5; ENST00000598367.5; ENST00000600092.5; ENST00000594907.5; ENST00000325495.9
External Link	RMBase: m6A_site_416317
mod ID: M6ASITE039263		Click to Show/Hide the Full List
mod site	chr19:8468820-8468821:+		[4]
Sequence	TTCTTCCCTCCTGAGCGTCCACAACAACTTCCCCGTAAGTG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000348943.7; ENST00000600806.5; ENST00000620401.4; ENST00000597270.1; ENST00000325495.9; ENST00000598367.5; ENST00000594907.5; ENST00000600092.5; ENST00000601645.5
External Link	RMBase: m6A_site_416318
mod ID: M6ASITE039264		Click to Show/Hide the Full List
mod site	chr19:8468823-8468824:+		[4]
Sequence	TTCCCTCCTGAGCGTCCACAACAACTTCCCCGTAAGTGTTT
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000600092.5; ENST00000600806.5; ENST00000620401.4; ENST00000597270.1; ENST00000325495.9; ENST00000348943.7; ENST00000594907.5; ENST00000598367.5; ENST00000601645.5
External Link	RMBase: m6A_site_416319
mod ID: M6ASITE039265		Click to Show/Hide the Full List
mod site	chr19:8471356-8471357:+		[5]
Sequence	GGTATTGGCATGGGGTTAGGACCAGGAGGGCAACCCATTGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; HepG2; U2OS; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000325495.9; ENST00000597270.1; ENST00000600092.5; ENST00000594907.5; ENST00000620401.4; ENST00000598367.5; ENST00000600806.5; ENST00000348943.7; ENST00000601645.5
External Link	RMBase: m6A_site_416320
mod ID: M6ASITE039266		Click to Show/Hide the Full List
mod site	chr19:8471385-8471386:+		[6]
Sequence	GCAACCCATTGATGCCAATCACCTGAATAAAGGCATCGGAA
Motif Score	2.026654762
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000325495.9; ENST00000600806.5; ENST00000600092.5; ENST00000597270.1; ENST00000594907.5; ENST00000620401.4; ENST00000601645.5; ENST00000348943.7; ENST00000598367.5
External Link	RMBase: m6A_site_416321
mod ID: M6ASITE039267		Click to Show/Hide the Full List
mod site	chr19:8471412-8471413:+		[5]
Sequence	TAAAGGCATCGGAATGGGAAACATAGGTCCCGCAGGTGAGA
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34; hESC-HEK293T; HepG2; U2OS; hNPCs; fibroblasts; A549; H1299; Huh7; endometrial
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000325495.9; ENST00000597270.1; ENST00000600806.5; ENST00000598367.5; ENST00000594907.5; ENST00000348943.7; ENST00000620401.4; ENST00000600092.5
External Link	RMBase: m6A_site_416322
mod ID: M6ASITE039268		Click to Show/Hide the Full List
mod site	chr19:8474199-8474200:+		[5]
Sequence	CTTTGGTGGTGGTATGGAAAACATGGGTCGATTTGGATCTG
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34; hESC-HEK293T; HepG2; U2OS; hNPCs; fibroblasts; A549; H1299; Huh7
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000348943.7; ENST00000600092.5; ENST00000594907.5; ENST00000597270.1; ENST00000598367.5; ENST00000325495.9; ENST00000600806.5; ENST00000620401.4
External Link	RMBase: m6A_site_416323
mod ID: M6ASITE039269		Click to Show/Hide the Full List
mod site	chr19:8474226-8474227:+		[5]
Sequence	TCGATTTGGATCTGGGATGAACATGGGCAGGATAAATGGTA
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD34; hESC-HEK293T; HepG2; U2OS; hNPCs; fibroblasts; A549; H1299; Huh7
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000620401.4; ENST00000598367.5; ENST00000325495.9; ENST00000597270.1; ENST00000600092.5; ENST00000348943.7; ENST00000600806.5; ENST00000594907.5
External Link	RMBase: m6A_site_416324
mod ID: M6ASITE039270		Click to Show/Hide the Full List
mod site	chr19:8485752-8485753:+		[5]
Sequence	GCGCATGGGCCTGGTCATGGACCGCATGGGCTCCGTGGAGC
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; LCLs; CD8T; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000600806.5; ENST00000597081.1; ENST00000620401.4; ENST00000325495.9; ENST00000348943.7; ENST00000597270.1
External Link	RMBase: m6A_site_416325
mod ID: M6ASITE039271		Click to Show/Hide the Full List
mod site	chr19:8485850-8485851:+		[5]
Sequence	GCATTGAGCGCATGGGCCAGACCATGGAGCGCATTGGCTCT
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; A549; U2OS; H1A; H1B; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000348943.7; ENST00000597081.1; ENST00000325495.9; ENST00000597270.1; ENST00000600806.5; ENST00000620401.4
External Link	RMBase: m6A_site_416326
mod ID: M6ASITE039272		Click to Show/Hide the Full List
mod site	chr19:8485946-8485947:+		[5]
Sequence	CCATCGACCGTGTGGGCCAGACCATTGAGCGCATGGGCTCT
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; A549; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; TREX; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000348943.7; ENST00000600806.5; ENST00000596295.1; ENST00000597081.1; ENST00000325495.9; ENST00000620401.4; ENST00000597270.1
External Link	RMBase: m6A_site_416327
mod ID: M6ASITE039273		Click to Show/Hide the Full List
mod site	chr19:8487038-8487039:+		[4]
Sequence	TTCAGCTGCCATTCGATTTCACATGGAAGATGCTAAAGGAC
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000600806.5; ENST00000596295.1; ENST00000325495.9; ENST00000597081.1; ENST00000620401.4; ENST00000598999.1; ENST00000348943.7
External Link	RMBase: m6A_site_416328
mod ID: M6ASITE039274		Click to Show/Hide the Full List
mod site	chr19:8487057-8487058:+		[9]
Sequence	CACATGGAAGATGCTAAAGGACAAATTCAACGAGTGCGGTA
Motif Score	3.643047619
Cell/Tissue List	CD34; HepG2; hESC-HEK293T; Huh7; AML
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000596295.1; ENST00000325495.9; ENST00000597081.1; ENST00000620401.4; ENST00000598999.1; ENST00000348943.7; ENST00000600806.5
External Link	RMBase: m6A_site_416329
mod ID: M6ASITE039275		Click to Show/Hide the Full List
mod site	chr19:8487146-8487147:+		[10]
Sequence	GCAGCCGAGTCAGCAGCAAAACCTCCCTCCCAGCCCCCTCC
Motif Score	2.185083333
Cell/Tissue List	HepG2; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000600806.5; ENST00000325495.9; ENST00000596295.1; ENST00000598999.1; ENST00000348943.7; ENST00000620401.4
External Link	RMBase: m6A_site_416330
mod ID: M6ASITE039276		Click to Show/Hide the Full List
mod site	chr19:8488406-8488407:+		[11]
Sequence	ACTTTGTAAAATGTATGGGAACTTTCTGCCTATAAAGCTGG
Motif Score	3.373380952
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000602219.1; ENST00000325495.9; ENST00000600806.5; ENST00000596295.1; ENST00000348943.7; ENST00000620401.4
External Link	RMBase: m6A_site_416331
mod ID: M6ASITE039277		Click to Show/Hide the Full List
mod site	chr19:8488655-8488656:+		[5]
Sequence	CAAAATCTAACAAAATCGGGACTGAGTGTCGTCTCTTCTTC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000602219.1; ENST00000620401.4; ENST00000348943.7; ENST00000325495.9; ENST00000600806.5; ENST00000596295.1
External Link	RMBase: m6A_site_416332
mod ID: M6ASITE039278		Click to Show/Hide the Full List
mod site	chr19:8488708-8488709:+		[4]
Sequence	AGGCCACGTGCTGTACGCCGACATCAAGATGGAGAATGGGA
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000348943.7; ENST00000620401.4; ENST00000602219.1; ENST00000325495.9; ENST00000600806.5; ENST00000596295.1
External Link	RMBase: m6A_site_416333
mod ID: M6ASITE039279		Click to Show/Hide the Full List
mod site	chr19:8488828-8488829:+		[6]
Sequence	GCTGAGTGGCCGAGAGATTGACGTTCGAATTGATAGAAACG
Motif Score	2.833690476
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000325495.9; ENST00000602219.1; ENST00000348943.7; ENST00000620401.4; ENST00000600806.5; ENST00000596295.1
External Link	RMBase: m6A_site_416334
mod ID: M6ASITE039280		Click to Show/Hide the Full List
mod site	chr19:8488871-8488872:+		[5]
Sequence	TAAGCAGTTGCCTTTTTTAAACATCGATACGAGACCTCTGA
Motif Score	2.20572619
Cell/Tissue List	HeLa; hESC-HEK293T; HepG2; H1299; MM6; endometrial; AML
Seq Type List	m6A-seq; MAZTER-seq; miCLIP
Transcript ID List	ENST00000325495.9; ENST00000348943.7; ENST00000600806.5; ENST00000596295.1; ENST00000620401.4; ENST00000602219.1
External Link	RMBase: m6A_site_416335
mod ID: M6ASITE039281		Click to Show/Hide the Full List
mod site	chr19:8488879-8488880:+		[6]
Sequence	TGCCTTTTTTAAACATCGATACGAGACCTCTGAATTTGTAT
Motif Score	2.084416667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000325495.9; ENST00000348943.7; ENST00000596295.1; ENST00000600806.5; ENST00000602219.1; ENST00000620401.4
External Link	RMBase: m6A_site_416336
mod ID: M6ASITE039282		Click to Show/Hide the Full List
mod site	chr19:8488884-8488885:+		[5]
Sequence	TTTTTAAACATCGATACGAGACCTCTGAATTTGTATTTTTT
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; HepG2; H1299; MM6; AML
Seq Type List	m6A-seq; DART-seq; miCLIP
Transcript ID List	ENST00000596295.1; ENST00000325495.9; ENST00000348943.7; ENST00000600806.5; ENST00000620401.4; ENST00000602219.1
External Link	RMBase: m6A_site_416337
mod ID: M6ASITE039283		Click to Show/Hide the Full List
mod site	chr19:8488912-8488913:+		[6]
Sequence	ATTTGTATTTTTTCTTGTTAACCATTTTAATTTGTTGGCTG
Motif Score	2.147452381
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000620401.4; ENST00000596295.1; ENST00000600806.5; ENST00000348943.7; ENST00000325495.9; ENST00000602219.1
External Link	RMBase: m6A_site_416338
mod ID: M6ASITE039284		Click to Show/Hide the Full List
mod site	chr19:8488985-8488986:+		[6]
Sequence	TTTTTGGGGTAATTTGAATTACTTTTTTAATGACTGGGGTT
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000600806.5; ENST00000325495.9; ENST00000602219.1; ENST00000348943.7; ENST00000620401.4
External Link	RMBase: m6A_site_416339
mod ID: M6ASITE039285		Click to Show/Hide the Full List
mod site	chr19:8488997-8488998:+		[6]
Sequence	TTTGAATTACTTTTTTAATGACTGGGGTTCCATTTGACTGT
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000325495.9; ENST00000602219.1; ENST00000348943.7; ENST00000620401.4; ENST00000600806.5
External Link	RMBase: m6A_site_416340
mod ID: M6ASITE039286		Click to Show/Hide the Full List
mod site	chr19:8489013-8489014:+		[6]
Sequence	AATGACTGGGGTTCCATTTGACTGTTTGCATTGAGATTGCA
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000348943.7; ENST00000602219.1; ENST00000325495.9; ENST00000600806.5; ENST00000620401.4
External Link	RMBase: m6A_site_416341
mod ID: M6ASITE039287		Click to Show/Hide the Full List
mod site	chr19:8489072-8489073:+		[6]
Sequence	GTAGTTGTGGCATCTTGTTGACATCGAATATGACTTTGATA
Motif Score	2.859755952
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000602219.1; ENST00000620401.4; ENST00000348943.7; ENST00000325495.9; ENST00000600806.5
External Link	RMBase: m6A_site_416342
mod ID: M6ASITE039288		Click to Show/Hide the Full List
mod site	chr19:8489084-8489085:+		[6]
Sequence	TCTTGTTGACATCGAATATGACTTTGATAATAAATACCGGT
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000325495.9; ENST00000348943.7; ENST00000602219.1; ENST00000600806.5; ENST00000620401.4
External Link	RMBase: m6A_site_416343

N7-methylguanosine (m7G)

In total 1 m6A sequence/site(s) in this target gene
mod ID: m7GSITE000055		Click to Show/Hide the Full List
mod site	chr19:8444970-8444971:+		[12]
Sequence	CAGCGCGGTGCAGCCCGTTCGCTCACACAAAGCCCAGACGC
Cell/Tissue List	A549; HeLa; HepG2
Seq Type List	BoRed-seq&m7G-RIP-seq; m7G-seq
Transcript ID List	ENST00000600092.5; ENST00000597813.5; ENST00000348943.7
External Link	RMBase: m7G_site_442

Ref 1	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 2	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 3	Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6784-6789. doi: 10.1073/pnas.1817334116. Epub 2019 Mar 14.
Ref 4	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 5	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 6	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 7	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 8	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 9	Suppression of m(6)A reader Ythdf2 promotes hematopoietic stem cell expansion. Cell Res. 2018 Sep;28(9):904-917. doi: 10.1038/s41422-018-0072-0. Epub 2018 Jul 31.
Ref 10	Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature. 2012 Apr 29;485(7397):201-6. doi: 10.1038/nature11112.
Ref 11	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 12	METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Mol Cell. 2019 Jun 20;74(6):1278-1290.e9. doi: 10.1016/j.molcel.2019.03.040. Epub 2019 Apr 25.

Epigenetic Target Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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