Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00124)

Target Name	C-X3-C motif chemokine ligand 1 (CX3CL1)
Synonyms	NTN; C3Xkine; ABCD-3; CXC3C; CXC3; SCYD1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); chemokine (C-X3-C motif) ligand 1 Click to Show/Hide
Gene Name	CX3CL1
Sequence	MAPISLSWLLRLATFCHLTVLLAGQHHGVTKCNITCSKMTSKIPVALLIHYQQNQASCGKRAIILETRQHRLFCADPKEQWVKDAMQHLDRQAAALTRNGGTFEKQIGEVKPRTTPAAGGMDESVVLEPEATGESSSLEPTPSSQEAQRALGTSPELPTGVTGSSGTRLPPTPKAQDGGPVGTELFRVPPVSTAATWQSSAPHQPGPSLWAEAKTSEAPSTQDPSTQASTASSPAPEENAPSEGQRVWGQGQSPRPENSLEREEMGPVPAHTDAFQDWGPGSMAHVSVVPVSSEGTPSREPVASGSWTPKAEEPIHATMDPQRLGVLITPVPDAQAATRRQAVGLLAFLGLLFCLGVAMFTYQSLQGCPRKMAGEMAEGLRYIPRSCGSNSYVLVPV Click to Show/Hide
Family	Intercrine delta family
Function	Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1 (PubMed:9782118, PubMed:12055230, PubMed:23125415, PubMed:9931005, PubMed:21829356). The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis (PubMed:9024663, PubMed:9177350, PubMed:9782118, PubMed:12055230). Regulates leukocyte adhesion and migration processes at the endothelium (PubMed:9024663, PubMed:9177350). Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner (PubMed:23125415, PubMed:24789099). In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins (PubMed:23125415, PubMed:24789099). In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1 (PubMed:23125415, PubMed:24789099). Click to Show/Hide
Gene ID	6376
HGNC ID	HGNC:10647
Ensembl Gene ID	ENSG00000006210
KEGG ID	hsa:6376
Chromosomal Location	16q21

RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00124)

C-X3-C motif chemokine ligand 1 (CX3CL1)

Adenosine-to-Inosine editing (A-to-I)

In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE007378		Click to Show/Hide the Full List
mod site	chr16:57378976-57378977:+		[1]
Sequence	CTTGCTGGCTGTGTGACCTTAGCAGGTCCCTGTCACTCTCA
Transcript ID List	rmsk_4543544; ENST00000563383.1; ENST00000565912.1; ENST00000564948.1; ENST00000006053.7
External Link	RMBase: RNA-editing_site_51454

N6-methyladenosine (m6A)

In total 54 m6A sequence/site(s) in this target gene
mod ID: M6ASITE027423		Click to Show/Hide the Full List
mod site	chr16:57372495-57372496:+		[2]
Sequence	TCTCTGGCGGCGGCAAGGGGACAGCACTGAGCTCTGCCGCC
Motif Score	3.643047619
Cell/Tissue List	HepG2; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000563383.1; ENST00000006053.7
External Link	RMBase: m6A_site_322967
mod ID: M6ASITE027424		Click to Show/Hide the Full List
mod site	chr16:57372548-57372549:+		[3]
Sequence	CCTGCCTGGCCCCCGCCGGGACTCTTGCCCACCCTCAGCCA
Motif Score	4.065041667
Cell/Tissue List	HepG2; A549; GSC-11; iSLK; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000564948.1; ENST00000563383.1; ENST00000006053.7
External Link	RMBase: m6A_site_322968
mod ID: M6ASITE027425		Click to Show/Hide the Full List
mod site	chr16:57376993-57376994:+		[3]
Sequence	AGGCTCCCCAGGTCAGTTAAACAATCTTCCTGGCAGAACCA
Motif Score	2.20572619
Cell/Tissue List	HepG2; A549; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000563383.1; ENST00000564948.1; ENST00000565912.1
External Link	RMBase: m6A_site_322969
mod ID: M6ASITE027426		Click to Show/Hide the Full List
mod site	chr16:57377010-57377011:+		[3]
Sequence	TAAACAATCTTCCTGGCAGAACCAAGAACTGAGCCGGGCCA
Motif Score	2.930744048
Cell/Tissue List	HepG2; A549; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000563383.1; ENST00000565912.1; ENST00000564948.1
External Link	RMBase: m6A_site_322970
mod ID: M6ASITE027427		Click to Show/Hide the Full List
mod site	chr16:57377017-57377018:+		[3]
Sequence	TCTTCCTGGCAGAACCAAGAACTGAGCCGGGCCAGGACCAT
Motif Score	3.373380952
Cell/Tissue List	HepG2; A549; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000565912.1; ENST00000563383.1; ENST00000006053.7; ENST00000564948.1
External Link	RMBase: m6A_site_322971
mod ID: M6ASITE027428		Click to Show/Hide the Full List
mod site	chr16:57377033-57377034:+		[3]
Sequence	AAGAACTGAGCCGGGCCAGGACCATTCAGGGACCGTGGCAG
Motif Score	3.622404762
Cell/Tissue List	HepG2; A549; GSC-11; endometrial; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000564948.1; ENST00000006053.7; ENST00000563383.1; ENST00000565912.1
External Link	RMBase: m6A_site_322972
mod ID: M6ASITE027429		Click to Show/Hide the Full List
mod site	chr16:57377044-57377045:+		[3]
Sequence	CGGGCCAGGACCATTCAGGGACCGTGGCAGAGGGTGGGGAC
Motif Score	3.622404762
Cell/Tissue List	HepG2; A549; GSC-11; endometrial; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000565912.1; ENST00000564948.1; ENST00000563383.1
External Link	RMBase: m6A_site_322973
mod ID: M6ASITE027430		Click to Show/Hide the Full List
mod site	chr16:57377063-57377064:+		[2]
Sequence	GACCGTGGCAGAGGGTGGGGACTTTGGAGACAGGATGACTC
Motif Score	4.065041667
Cell/Tissue List	HepG2; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000563383.1; ENST00000564948.1; ENST00000006053.7; ENST00000565912.1
External Link	RMBase: m6A_site_322974
mod ID: M6ASITE027431		Click to Show/Hide the Full List
mod site	chr16:57377072-57377073:+		[2]
Sequence	AGAGGGTGGGGACTTTGGAGACAGGATGACTCTGTGGCTCT
Motif Score	2.897386905
Cell/Tissue List	HepG2; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000563383.1; ENST00000564948.1; ENST00000006053.7; ENST00000565912.1
External Link	RMBase: m6A_site_322975
mod ID: M6ASITE027432		Click to Show/Hide the Full List
mod site	chr16:57379598-57379599:+		[2]
Sequence	GGGAAGCCAGATGCCCACAGACATCCCTGCTGACCAGGAAC
Motif Score	2.897386905
Cell/Tissue List	HepG2; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000563383.1; ENST00000565912.1; ENST00000564948.1; rmsk_4543547
External Link	RMBase: m6A_site_322976
mod ID: M6ASITE027433		Click to Show/Hide the Full List
mod site	chr16:57379617-57379618:+		[2]
Sequence	GACATCCCTGCTGACCAGGAACCTCTTTGAACTCAGGACAG
Motif Score	2.930744048
Cell/Tissue List	HepG2; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000564948.1; rmsk_4543547; ENST00000565912.1; ENST00000006053.7; ENST00000563383.1
External Link	RMBase: m6A_site_322977
mod ID: M6ASITE027434		Click to Show/Hide the Full List
mod site	chr16:57379627-57379628:+		[2]
Sequence	CTGACCAGGAACCTCTTTGAACTCAGGACAGCACCACGGTG
Motif Score	3.373380952
Cell/Tissue List	HepG2; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; rmsk_4543547; ENST00000565912.1; ENST00000564948.1; ENST00000563383.1
External Link	RMBase: m6A_site_322978
mod ID: M6ASITE027435		Click to Show/Hide the Full List
mod site	chr16:57379634-57379635:+		[2]
Sequence	GGAACCTCTTTGAACTCAGGACAGCACCACGGTGTGACGAA
Motif Score	3.643047619
Cell/Tissue List	HepG2; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000565912.1; ENST00000564948.1; ENST00000006053.7; rmsk_4543547; ENST00000563383.1
External Link	RMBase: m6A_site_322979
mod ID: M6ASITE027436		Click to Show/Hide the Full List
mod site	chr16:57379718-57379719:+		[4]
Sequence	GCTTTGCTCATCCACTATCAACAGAACCAGGCATCATGCGG
Motif Score	2.173910714
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000565912.1; ENST00000563383.1; ENST00000006053.7; ENST00000564948.1
External Link	RMBase: m6A_site_322980
mod ID: M6ASITE027437		Click to Show/Hide the Full List
mod site	chr16:57379723-57379724:+		[2]
Sequence	GCTCATCCACTATCAACAGAACCAGGCATCATGCGGCAAAC
Motif Score	2.930744048
Cell/Tissue List	HepG2; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000565912.1; ENST00000564948.1; ENST00000563383.1
External Link	RMBase: m6A_site_322981
mod ID: M6ASITE027438		Click to Show/Hide the Full List
mod site	chr16:57382041-57382042:+		[2]
Sequence	CCTTGTAGCTTGGAGACGAGACAGCACAGGCTGTTCTGTGC
Motif Score	2.897386905
Cell/Tissue List	HepG2; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000565912.1; ENST00000006053.7; ENST00000563383.1; ENST00000564948.1
External Link	RMBase: m6A_site_322982
mod ID: M6ASITE027439		Click to Show/Hide the Full List
mod site	chr16:57382106-57382107:+		[3]
Sequence	GGACGCGATGCAGCATCTGGACCGCCAGGCTGCTGCCCTAA
Motif Score	3.622404762
Cell/Tissue List	HepG2; A549; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000565912.1; ENST00000564948.1; ENST00000006053.7; ENST00000563383.1
External Link	RMBase: m6A_site_322983
mod ID: M6ASITE027440		Click to Show/Hide the Full List
mod site	chr16:57382177-57382178:+		[3]
Sequence	TCGGCGAGGTGAAGCCCAGGACCACCCCTGCCGCCGGGGGA
Motif Score	3.622404762
Cell/Tissue List	HepG2; A549; Huh7; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000565912.1; ENST00000564948.1; ENST00000563383.1; ENST00000006053.7
External Link	RMBase: m6A_site_322984
mod ID: M6ASITE027441		Click to Show/Hide the Full List
mod site	chr16:57382294-57382295:+		[3]
Sequence	AAGCACAGAGGGCCCTGGGGACCTCCCCAGAGCTGCCGACG
Motif Score	3.622404762
Cell/Tissue List	HepG2; A549; GSC-11; iSLK; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000565912.1; ENST00000563383.1; ENST00000006053.7; ENST00000564948.1
External Link	RMBase: m6A_site_322985
mod ID: M6ASITE027442		Click to Show/Hide the Full List
mod site	chr16:57382336-57382337:+		[3]
Sequence	GCGTGACTGGTTCCTCAGGGACCAGGCTCCCCCCGACGCCA
Motif Score	3.622404762
Cell/Tissue List	HepG2; A549; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000564948.1; ENST00000563383.1; ENST00000565912.1
External Link	RMBase: m6A_site_322986
mod ID: M6ASITE027443		Click to Show/Hide the Full List
mod site	chr16:57382480-57382481:+		[3]
Sequence	GCCTCTGGGCTGAGGCAAAGACCTCTGAGGCCCCGTCCACC
Motif Score	2.876744048
Cell/Tissue List	HepG2; A549; H1A; H1B; GM12878; Huh7; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000563383.1; ENST00000565912.1; ENST00000006053.7
External Link	RMBase: m6A_site_322987
mod ID: M6ASITE027444		Click to Show/Hide the Full List
mod site	chr16:57382505-57382506:+		[3]
Sequence	TGAGGCCCCGTCCACCCAGGACCCCTCCACCCAGGCCTCCA
Motif Score	3.622404762
Cell/Tissue List	HepG2; A549; H1A; H1B; GM12878; Huh7; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000565912.1; ENST00000563383.1
External Link	RMBase: m6A_site_322988
mod ID: M6ASITE027445		Click to Show/Hide the Full List
mod site	chr16:57382590-57382591:+		[3]
Sequence	CAGCGTGTGTGGGGTCAGGGACAGAGCCCCAGGCCAGAGAA
Motif Score	3.643047619
Cell/Tissue List	HepG2; brain; A549; U2OS; H1A; H1B; GM12878; Huh7; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; m6A-REF-seq; MeRIP-seq
Transcript ID List	ENST00000563383.1; ENST00000006053.7; ENST00000565912.1
External Link	RMBase: m6A_site_322989
mod ID: M6ASITE027446		Click to Show/Hide the Full List
mod site	chr16:57382610-57382611:+		[3]
Sequence	ACAGAGCCCCAGGCCAGAGAACTCTCTGGAGCGGGAGGAGA
Motif Score	3.373380952
Cell/Tissue List	HepG2; A549; U2OS; H1A; H1B; GM12878; Huh7; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000565912.1; ENST00000563383.1
External Link	RMBase: m6A_site_322990
mod ID: M6ASITE027447		Click to Show/Hide the Full List
mod site	chr16:57382667-57382668:+		[3]
Sequence	GCACACGGATGCCTTCCAGGACTGGGGGCCTGGCAGCATGG
Motif Score	4.065041667
Cell/Tissue List	HepG2; A549; U2OS; H1A; H1B; GM12878; Huh7; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000563383.1; ENST00000565912.1; ENST00000006053.7
External Link	RMBase: m6A_site_322991
mod ID: M6ASITE027448		Click to Show/Hide the Full List
mod site	chr16:57382723-57382724:+		[3]
Sequence	TCCCTGTCTCCTCAGAAGGGACCCCCAGCAGGGAGCCAGTG
Motif Score	3.622404762
Cell/Tissue List	HepG2; A549; H1A; H1B; GM12878; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000563383.1; ENST00000565912.1; ENST00000006053.7
External Link	RMBase: m6A_site_322992
mod ID: M6ASITE027449		Click to Show/Hide the Full List
mod site	chr16:57382759-57382760:+		[3]
Sequence	CAGTGGCTTCAGGCAGCTGGACCCCTAAGGCTGAGGAACCC
Motif Score	3.622404762
Cell/Tissue List	HepG2; A549; H1A; H1B; GM12878; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000565912.1; ENST00000006053.7; ENST00000563383.1
External Link	RMBase: m6A_site_322993
mod ID: M6ASITE027450		Click to Show/Hide the Full List
mod site	chr16:57382776-57382777:+		[3]
Sequence	TGGACCCCTAAGGCTGAGGAACCCATCCATGCCACCATGGA
Motif Score	2.930744048
Cell/Tissue List	HepG2; A549; H1A; H1B; GSC-11; iSLK; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000563383.1; ENST00000565912.1
External Link	RMBase: m6A_site_322994
mod ID: M6ASITE027451		Click to Show/Hide the Full List
mod site	chr16:57382796-57382797:+		[3]
Sequence	ACCCATCCATGCCACCATGGACCCCCAGAGGCTGGGCGTCC
Motif Score	3.622404762
Cell/Tissue List	HepG2; A549; H1A; GSC-11; iSLK; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000563383.1; ENST00000565912.1
External Link	RMBase: m6A_site_322995
mod ID: M6ASITE027452		Click to Show/Hide the Full List
mod site	chr16:57383032-57383033:+		[5]
Sequence	ATGTCCTGGTGCCCGTGTGAACTCCTCTGGCCTGTGTCTAG
Motif Score	3.373380952
Cell/Tissue List	Huh7; iSLK
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000565912.1; ENST00000563383.1
External Link	RMBase: m6A_site_322996
mod ID: M6ASITE027453		Click to Show/Hide the Full List
mod site	chr16:57383066-57383067:+		[5]
Sequence	TGTCTAGTTGTTTGATTCAGACAGCTGCCTGGGATCCCTCA
Motif Score	2.897386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000563383.1; ENST00000006053.7; ENST00000565912.1
External Link	RMBase: m6A_site_322997
mod ID: M6ASITE027454		Click to Show/Hide the Full List
mod site	chr16:57383228-57383229:+		[2]
Sequence	CCATTCTCCACCTGCCAGGGACAGAGGGGGTGGCCTCCCAA
Motif Score	3.643047619
Cell/Tissue List	HepG2; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000563383.1; ENST00000565912.1; ENST00000006053.7
External Link	RMBase: m6A_site_322998
mod ID: M6ASITE027455		Click to Show/Hide the Full List
mod site	chr16:57383266-57383267:+		[2]
Sequence	CAACTCACCCCAGCCCCAAAACTCTCCTCTGCTGCTGGCTG
Motif Score	2.627720238
Cell/Tissue List	HepG2; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000565912.1; ENST00000006053.7; ENST00000563383.1
External Link	RMBase: m6A_site_322999
mod ID: M6ASITE027456		Click to Show/Hide the Full List
mod site	chr16:57383325-57383326:+		[5]
Sequence	CGCCATCCCAGCCCCAATGAACAATTATTTATTAAATGCCC
Motif Score	2.951386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000565912.1; ENST00000563383.1; ENST00000006053.7
External Link	RMBase: m6A_site_323000
mod ID: M6ASITE027457		Click to Show/Hide the Full List
mod site	chr16:57383521-57383522:+		[4]
Sequence	CCCCCAGCCCCATCCTCTGTACAGAGCCCACGCCCCCACTG
Motif Score	2.856142857
Cell/Tissue List	brain
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000565912.1; ENST00000563383.1; ENST00000006053.7
External Link	RMBase: m6A_site_323001
mod ID: M6ASITE027458		Click to Show/Hide the Full List
mod site	chr16:57383892-57383893:+		[6]
Sequence	ATGGACTAACTTGTCTTTGGACCCTGAGGCCCAGAGGGCCT
Motif Score	3.622404762
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000565912.1; ENST00000563383.1; ENST00000006053.7
External Link	RMBase: m6A_site_323002
mod ID: M6ASITE027459		Click to Show/Hide the Full List
mod site	chr16:57383934-57383935:+		[4]
Sequence	CAAGGGAGTGAGTTGATAGCACAGACCCTGCCCTGTGGGCC
Motif Score	2.830589286
Cell/Tissue List	brain
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000563383.1; ENST00000565912.1; ENST00000006053.7
External Link	RMBase: m6A_site_323003
mod ID: M6ASITE027460		Click to Show/Hide the Full List
mod site	chr16:57383938-57383939:+		[6]
Sequence	GGAGTGAGTTGATAGCACAGACCCTGCCCTGTGGGCCCCCA
Motif Score	2.876744048
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000563383.1; ENST00000565912.1; ENST00000006053.7
External Link	RMBase: m6A_site_323004
mod ID: M6ASITE027461		Click to Show/Hide the Full List
mod site	chr16:57383981-57383982:+		[6]
Sequence	TGGAAATGGGCAGAGCAGAGACCATCCCTGAAGGCCCCGCC
Motif Score	2.876744048
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000565912.1; ENST00000563383.1; ENST00000006053.7
External Link	RMBase: m6A_site_323005
mod ID: M6ASITE027462		Click to Show/Hide the Full List
mod site	chr16:57384019-57384020:+		[6]
Sequence	GCCCAGGCTTAGTCACTGAGACAGCCCGGGCTCTGCCTCCC
Motif Score	2.897386905
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000006053.7; ENST00000563383.1; ENST00000565912.1
External Link	RMBase: m6A_site_323006
mod ID: M6ASITE027463		Click to Show/Hide the Full List
mod site	chr16:57384071-57384072:+		[5]
Sequence	AGAGGGAGGGAGGGCTCCAGACACATGTCCAAGAAGCCCAG
Motif Score	2.897386905
Cell/Tissue List	Huh7; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000563383.1; ENST00000565912.1; ENST00000006053.7
External Link	RMBase: m6A_site_323007
mod ID: M6ASITE027464		Click to Show/Hide the Full List
mod site	chr16:57384135-57384136:+		[5]
Sequence	TTCCTGATGCTTCTTCAGAGACTCCTGCAGGCAGCCAGGCC
Motif Score	3.319380952
Cell/Tissue List	Huh7; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000563383.1; ENST00000006053.7; ENST00000565912.1
External Link	RMBase: m6A_site_323008
mod ID: M6ASITE027465		Click to Show/Hide the Full List
mod site	chr16:57384161-57384162:+		[5]
Sequence	GCAGGCAGCCAGGCCACAAGACCCTTGTGGTCCCACCCCAC
Motif Score	2.876744048
Cell/Tissue List	Huh7; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000006053.7; ENST00000563383.1; ENST00000565912.1
External Link	RMBase: m6A_site_323009
mod ID: M6ASITE027466		Click to Show/Hide the Full List
mod site	chr16:57384240-57384241:+		[5]
Sequence	ACCTCTCTCACTCCTTGAAAACACTGTTCTCTGCCCTCCAA
Motif Score	2.20572619
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000563383.1; ENST00000565912.1
External Link	RMBase: m6A_site_323010
mod ID: M6ASITE027467		Click to Show/Hide the Full List
mod site	chr16:57384262-57384263:+		[5]
Sequence	ACTGTTCTCTGCCCTCCAAGACCTTCTCCTTCACCTTTGTC
Motif Score	2.876744048
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000565912.1; ENST00000563383.1
External Link	RMBase: m6A_site_323011
mod ID: M6ASITE027468		Click to Show/Hide the Full List
mod site	chr16:57384293-57384294:+		[4]
Sequence	CACCTTTGTCCCCACCGCAGACAGGACCAGGGATTTCCATG
Motif Score	2.897386905
Cell/Tissue List	brain; Huh7
Seq Type List	m6A-REF-seq; MeRIP-seq
Transcript ID List	ENST00000565912.1; ENST00000563383.1; ENST00000006053.7
External Link	RMBase: m6A_site_323012
mod ID: M6ASITE027469		Click to Show/Hide the Full List
mod site	chr16:57384298-57384299:+		[5]
Sequence	TTGTCCCCACCGCAGACAGGACCAGGGATTTCCATGATGTT
Motif Score	3.622404762
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000563383.1; ENST00000006053.7; ENST00000565912.1
External Link	RMBase: m6A_site_323013
mod ID: M6ASITE027470		Click to Show/Hide the Full List
mod site	chr16:57384823-57384824:+		[6]
Sequence	GAGAGCCTTCCAGGGGTGGGACACCCTGTGATGGGGCCCTG
Motif Score	3.643047619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000563383.1; ENST00000006053.7; ENST00000565912.1
External Link	RMBase: m6A_site_323014
mod ID: M6ASITE027471		Click to Show/Hide the Full List
mod site	chr16:57384892-57384893:+		[3]
Sequence	AGTTGGTCCCCCTTCCATGGACTTTGTTAGTTTCTCCAAGC
Motif Score	4.065041667
Cell/Tissue List	HepG2; A549; GM12878; Huh7; GSC-11; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000565912.1; ENST00000563383.1; ENST00000006053.7
External Link	RMBase: m6A_site_323015
mod ID: M6ASITE027472		Click to Show/Hide the Full List
mod site	chr16:57384916-57384917:+		[3]
Sequence	TGTTAGTTTCTCCAAGCAGGACATGGACAAGGATGATCTAG
Motif Score	3.643047619
Cell/Tissue List	HepG2; A549; GM12878; Huh7; GSC-11; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000563383.1; ENST00000565912.1; ENST00000006053.7
External Link	RMBase: m6A_site_323016
mod ID: M6ASITE027473		Click to Show/Hide the Full List
mod site	chr16:57384922-57384923:+		[3]
Sequence	TTTCTCCAAGCAGGACATGGACAAGGATGATCTAGGAAGAC
Motif Score	3.643047619
Cell/Tissue List	HepG2; A549; GM12878; Huh7; GSC-11; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000563383.1; ENST00000565912.1
External Link	RMBase: m6A_site_323017
mod ID: M6ASITE027474		Click to Show/Hide the Full List
mod site	chr16:57384941-57384942:+		[3]
Sequence	GACAAGGATGATCTAGGAAGACTTTGGAAAGAGTAGGAAGA
Motif Score	3.319380952
Cell/Tissue List	HepG2; A549; GM12878; Huh7; GSC-11; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000565912.1; ENST00000563383.1
External Link	RMBase: m6A_site_323018
mod ID: M6ASITE027475		Click to Show/Hide the Full List
mod site	chr16:57384961-57384962:+		[3]
Sequence	ACTTTGGAAAGAGTAGGAAGACTTTGGAAAGACTTTTCCAA
Motif Score	3.319380952
Cell/Tissue List	HepG2; A549; GM12878; Huh7; GSC-11; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000563383.1; ENST00000565912.1
External Link	RMBase: m6A_site_323019
mod ID: M6ASITE027476		Click to Show/Hide the Full List
mod site	chr16:57384972-57384973:+		[3]
Sequence	AGTAGGAAGACTTTGGAAAGACTTTTCCAACCCTCATCACC
Motif Score	3.319380952
Cell/Tissue List	HepG2; A549; GM12878; Huh7; GSC-11; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000006053.7; ENST00000565912.1; ENST00000563383.1
External Link	RMBase: m6A_site_323020

Ref 1	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 2	Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.
Ref 3	Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13.
Ref 4	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 5	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 6	m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.

Epigenetic Target Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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