Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00087)

Target Name	HIF1A antisense RNA 2 (HIF1A-AS2)
Synonyms	3'aHIF-1A; aHIF; HIF1A antisense RNA 2 (non-protein coding) Click to Show/Hide
Gene Name	HIF1A-AS2
Family	Antisense RNAs
Gene ID	100750247
HGNC ID	HGNC:43015
Chromosomal Location	14q23.2

RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00087)

HIF1A antisense RNA 2 (HIF1A-AS2)

Adenosine-to-Inosine editing (A-to-I)

In total 28 m6A sequence/site(s) in this target gene
mod ID: A2ISITE006390		Click to Show/Hide the Full List
mod site	chr14:61726064-61726065:-		[1]
Sequence	CACTTTGGGAGGCTGAGGCAAGAGGATCACTTGAGGTCAGG
Transcript ID List	rmsk_4191458; ENST00000554254.1
External Link	RMBase: RNA-editing_site_38850
mod ID: A2ISITE006398		Click to Show/Hide the Full List
mod site	chr14:61743249-61743250:-		[1]
Sequence	GGAGAAACACTGTCTCTACTAAAAATACAAAATTAGCTGGG
Transcript ID List	ENST00000554254.1; rmsk_4191485
External Link	RMBase: RNA-editing_site_38858
mod ID: A2ISITE006399		Click to Show/Hide the Full List
mod site	chr14:61743369-61743370:-		[1]
Sequence	AATGTTTAAAAACAGTTGCTAGCTGGGCACAGTGGCTCACA
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38859
mod ID: A2ISITE006403		Click to Show/Hide the Full List
mod site	chr14:61748656-61748657:-		[2]
Sequence	ATTATTCATTTGAAGTCTAAATTTATTAATCTGTTAATGGG
Transcript ID List	rmsk_4191494; ENST00000554254.1
External Link	RMBase: RNA-editing_site_38863
mod ID: A2ISITE006404		Click to Show/Hide the Full List
mod site	chr14:61748695-61748696:-		[1]
Sequence	TTTTTGGTCTGCCATCTATTACTTTTAAAGCTTGGGCAAAT
Transcript ID List	rmsk_4191494; ENST00000554254.1
External Link	RMBase: RNA-editing_site_38864
mod ID: A2ISITE006405		Click to Show/Hide the Full List
mod site	chr14:61748718-61748719:-		[1]
Sequence	GAGTCAGGAAACTTAAGCTTACATTTTTGGTCTGCCATCTA
Transcript ID List	rmsk_4191494; ENST00000554254.1
External Link	RMBase: RNA-editing_site_38865
mod ID: A2ISITE006406		Click to Show/Hide the Full List
mod site	chr14:61748723-61748724:-		[1]
Sequence	CTTTAGAGTCAGGAAACTTAAGCTTACATTTTTGGTCTGCC
Transcript ID List	rmsk_4191494; ENST00000554254.1
External Link	RMBase: RNA-editing_site_38866
mod ID: A2ISITE006407		Click to Show/Hide the Full List
mod site	chr14:61748724-61748725:-		[2]
Sequence	ACTTTAGAGTCAGGAAACTTAAGCTTACATTTTTGGTCTGC
Transcript ID List	ENST00000554254.1; rmsk_4191494
External Link	RMBase: RNA-editing_site_38867
mod ID: A2ISITE006408		Click to Show/Hide the Full List
mod site	chr14:61748729-61748730:-		[2]
Sequence	GTTTGACTTTAGAGTCAGGAAACTTAAGCTTACATTTTTGG
Transcript ID List	ENST00000554254.1; rmsk_4191494
External Link	RMBase: RNA-editing_site_38868
mod ID: A2ISITE006409		Click to Show/Hide the Full List
mod site	chr14:61748739-61748740:-		[2]
Sequence	TTTGTTCTAAGTTTGACTTTAGAGTCAGGAAACTTAAGCTT
Transcript ID List	ENST00000554254.1; rmsk_4191494
External Link	RMBase: RNA-editing_site_38869
mod ID: A2ISITE006410		Click to Show/Hide the Full List
mod site	chr14:61748750-61748751:-		[2]
Sequence	AACAAACCAAATTTGTTCTAAGTTTGACTTTAGAGTCAGGA
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38870
mod ID: A2ISITE006411		Click to Show/Hide the Full List
mod site	chr14:61748760-61748761:-		[2]
Sequence	TTAAAACAAAAACAAACCAAATTTGTTCTAAGTTTGACTTT
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38871
mod ID: A2ISITE006412		Click to Show/Hide the Full List
mod site	chr14:61748778-61748779:-		[1]
Sequence	TTTTAAAACGCAGTATCATTAAAACAAAAACAAACCAAATT
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38872
mod ID: A2ISITE006413		Click to Show/Hide the Full List
mod site	chr14:61748809-61748810:-		[1]
Sequence	AATACAGGAGAAAAAGGATAAAGCTACTTTGTTTTAAAACG
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38873
mod ID: A2ISITE006414		Click to Show/Hide the Full List
mod site	chr14:61748810-61748811:-		[2]
Sequence	AAATACAGGAGAAAAAGGATAAAGCTACTTTGTTTTAAAAC
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38874
mod ID: A2ISITE006415		Click to Show/Hide the Full List
mod site	chr14:61748824-61748825:-		[2]
Sequence	ATTTTGTAAAAGAAAAATACAGGAGAAAAAGGATAAAGCTA
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38875
mod ID: A2ISITE006416		Click to Show/Hide the Full List
mod site	chr14:61748826-61748827:-		[1]
Sequence	CTATTTTGTAAAAGAAAAATACAGGAGAAAAAGGATAAAGC
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38876
mod ID: A2ISITE006417		Click to Show/Hide the Full List
mod site	chr14:61749712-61749713:-		[1]
Sequence	AAAAAAATTAAAATAGCTTTATTCTTTTTCTCCTGTATTTT
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38877
mod ID: A2ISITE006418		Click to Show/Hide the Full List
mod site	chr14:61749718-61749719:-		[3]
Sequence	TGCATTAAAAAAATTAAAATAGCTTTATTCTTTTTCTCCTG
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38878
mod ID: A2ISITE006419		Click to Show/Hide the Full List
mod site	chr14:61749720-61749721:-		[1]
Sequence	ACTGCATTAAAAAAATTAAAATAGCTTTATTCTTTTTCTCC
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38879
mod ID: A2ISITE006420		Click to Show/Hide the Full List
mod site	chr14:61749780-61749781:-		[1]
Sequence	GCTTAAGTCTCCTGACTCTAAAGTCAAACTTAGAACAAACT
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38880
mod ID: A2ISITE006421		Click to Show/Hide the Full List
mod site	chr14:61749781-61749782:-		[1]
Sequence	AGCTTAAGTCTCCTGACTCTAAAGTCAAACTTAGAACAAAC
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38881
mod ID: A2ISITE006422		Click to Show/Hide the Full List
mod site	chr14:61749796-61749797:-		[1]
Sequence	CAGACCAGAAATGTAAGCTTAAGTCTCCTGACTCTAAAGTC
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38882
mod ID: A2ISITE006423		Click to Show/Hide the Full List
mod site	chr14:61749801-61749802:-		[1]
Sequence	GATGGCAGACCAGAAATGTAAGCTTAAGTCTCCTGACTCTA
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38883
mod ID: A2ISITE006424		Click to Show/Hide the Full List
mod site	chr14:61749815-61749816:-		[1]
Sequence	CTCTAAAAGTAATAGATGGCAGACCAGAAATGTAAGCTTAA
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38884
mod ID: A2ISITE006425		Click to Show/Hide the Full List
mod site	chr14:61749822-61749823:-		[1]
Sequence	ACCCAAGCTCTAAAAGTAATAGATGGCAGACCAGAAATGTA
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38885
mod ID: A2ISITE006426		Click to Show/Hide the Full List
mod site	chr14:61749837-61749838:-		[1]
Sequence	CTCAAATGAAGATTTACCCAAGCTCTAAAAGTAATAGATGG
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38886
mod ID: A2ISITE006427		Click to Show/Hide the Full List
mod site	chr14:61749842-61749843:-		[1]
Sequence	TAGATCTCAAATGAAGATTTACCCAAGCTCTAAAAGTAATA
Transcript ID List	ENST00000554254.1
External Link	RMBase: RNA-editing_site_38887

N6-methyladenosine (m6A)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M6ASITE020040		Click to Show/Hide the Full List
mod site	chr14:61750961-61750962:-		[4]
Sequence	CGTCCCAGAATGGAGCCAAGACAAGGGAATAAACGAAATTC
Motif Score	2.897386905
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000554254.1
External Link	RMBase: m6A_site_250493

Ref 1	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 2	Widespread RNA editing of embedded alu elements in the human transcriptome. Genome Res. 2004 Sep;14(9):1719-25. doi: 10.1101/gr.2855504.
Ref 3	Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat Biotechnol. 2012 Feb 12;30(3):253-60. doi: 10.1038/nbt.2122.
Ref 4	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.

Epigenetic Target Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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