Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00073)

Target Name	F11 receptor (F11R)
Synonyms	PAM-1; JCAM; JAM-1; JAM-A; JAMA; CD321; JAM1; junctional adhesion molecule 1 Click to Show/Hide
Gene Name	F11R
Sequence	MGTKAQVERKLLCLFILAILLCSLALGSVTVHSSEPEVRIPENNPVKLSCAYSGFSSPRVEWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEGGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERNVGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSARSEGEFKQTSSFLV Click to Show/Hide
Family	Immunoglobulin superfamily
Function	Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840). Click to Show/Hide
Gene ID	50848
HGNC ID	HGNC:14685
Ensembl Gene ID	ENSG00000158769
KEGG ID	hsa:50848
Chromosomal Location	1q23.3

RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00073)

F11 receptor (F11R)

N4-acetylcytidine (ac4C)

In total 2 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000075		Click to Show/Hide the Full List
mod site	chr1:160997337-160997338:-
Sequence	CCCTACAGCTGTAGGAACTACTGTCCCAGAGCTGAGGCAAG
Cell/Tissue List	DLD1
Seq Type List	acRIP-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: ac4C_site_141
mod ID: AC4SITE000076		Click to Show/Hide the Full List
mod site	chr1:160997908-160997909:-		[1]
Sequence	CCTTCCCTTGGCTGGAACTACTGGACAGACCCTTTTGAGAT
Cell/Tissue List	H1
Seq Type List	ac4C-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: ac4C_site_142

Adenosine-to-Inosine editing (A-to-I)

In total 23 m6A sequence/site(s) in this target gene
mod ID: A2ISITE000166		Click to Show/Hide the Full List
mod site	chr1:160995629-160995630:-		[2]
Sequence	CCTCCTAAGTAGCTGGGACTATAGGCGTGTGCCACCATGCC
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: RNA-editing_site_10144
mod ID: A2ISITE000173		Click to Show/Hide the Full List
mod site	chr1:160996510-160996511:-		[3]
Sequence	CCTCCCAAAGTGATGGGATTACAGATGTGAGCCACCGTGCC
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: RNA-editing_site_10145
mod ID: A2ISITE000174		Click to Show/Hide the Full List
mod site	chr1:160996560-160996561:-		[4]
Sequence	GTTGGTCGGGCTGGTCTCAAACTCCTGACCTCTTGATCCGC
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: RNA-editing_site_10146
mod ID: A2ISITE000175		Click to Show/Hide the Full List
mod site	chr1:160996561-160996562:-		[4]
Sequence	TGTTGGTCGGGCTGGTCTCAAACTCCTGACCTCTTGATCCG
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: RNA-editing_site_10147
mod ID: A2ISITE000176		Click to Show/Hide the Full List
mod site	chr1:160996562-160996563:-		[3]
Sequence	ATGTTGGTCGGGCTGGTCTCAAACTCCTGACCTCTTGATCC
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: RNA-editing_site_10148
mod ID: A2ISITE000177		Click to Show/Hide the Full List
mod site	chr1:160996643-160996644:-		[4]
Sequence	TCTCCTGAGTAGCTGGGATTACGGGTGCGTGCCACCATGCC
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: RNA-editing_site_10149
mod ID: A2ISITE000178		Click to Show/Hide the Full List
mod site	chr1:160996941-160996942:-		[5]
Sequence	CAGAATTGAGTTTTCTATTAAGGATCCAAAAAGAAAAACAA
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: RNA-editing_site_10150
mod ID: A2ISITE000179		Click to Show/Hide the Full List
mod site	chr1:160997938-160997939:-		[4]
Sequence	AAAGCTGGAGCTGGTGGCTTAGGCCATCACCCTTCCCTTGG
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: RNA-editing_site_10151
mod ID: A2ISITE000180		Click to Show/Hide the Full List
mod site	chr1:160998025-160998026:-		[4]
Sequence	CATAGTGGTGCATGCCTGTAATCCCAGCTGCTCAGGAGCCT
Transcript ID List	ENST00000621309.4; rmsk_283427; ENST00000368026.11; ENST00000289779.7
External Link	RMBase: RNA-editing_site_10152
mod ID: A2ISITE000181		Click to Show/Hide the Full List
mod site	chr1:160998026-160998027:-		[6]
Sequence	GCATAGTGGTGCATGCCTGTAATCCCAGCTGCTCAGGAGCC
Transcript ID List	ENST00000289779.7; ENST00000621309.4; ENST00000368026.11; rmsk_283427
External Link	RMBase: RNA-editing_site_10153
mod ID: A2ISITE000182		Click to Show/Hide the Full List
mod site	chr1:160998042-160998043:-		[4]
Sequence	ATACAAAGTTAGCCAGGCATAGTGGTGCATGCCTGTAATCC
Transcript ID List	ENST00000368026.11; rmsk_283427; ENST00000289779.7; ENST00000621309.4
External Link	RMBase: RNA-editing_site_10154
mod ID: A2ISITE000183		Click to Show/Hide the Full List
mod site	chr1:160998052-160998053:-		[4]
Sequence	CCTACTAAAAATACAAAGTTAGCCAGGCATAGTGGTGCATG
Transcript ID List	rmsk_283427; ENST00000621309.4; ENST00000368026.11; ENST00000289779.7
External Link	RMBase: RNA-editing_site_10155
mod ID: A2ISITE000191		Click to Show/Hide the Full List
mod site	chr1:160998057-160998058:-		[4]
Sequence	GAAACCCTACTAAAAATACAAAGTTAGCCAGGCATAGTGGT
Transcript ID List	ENST00000621309.4; ENST00000368026.11; ENST00000289779.7; rmsk_283427
External Link	RMBase: RNA-editing_site_10156
mod ID: A2ISITE000199		Click to Show/Hide the Full List
mod site	chr1:160998065-160998066:-		[4]
Sequence	AACATGGAGAAACCCTACTAAAAATACAAAGTTAGCCAGGC
Transcript ID List	ENST00000621309.4; ENST00000289779.7; rmsk_283427; ENST00000368026.11
External Link	RMBase: RNA-editing_site_10157
mod ID: A2ISITE000200		Click to Show/Hide the Full List
mod site	chr1:160998066-160998067:-		[4]
Sequence	CAACATGGAGAAACCCTACTAAAAATACAAAGTTAGCCAGG
Transcript ID List	ENST00000368026.11; ENST00000621309.4; ENST00000289779.7; rmsk_283427
External Link	RMBase: RNA-editing_site_10158
mod ID: A2ISITE000201		Click to Show/Hide the Full List
mod site	chr1:160998069-160998070:-		[4]
Sequence	GACCAACATGGAGAAACCCTACTAAAAATACAAAGTTAGCC
Transcript ID List	ENST00000368026.11; rmsk_283427; ENST00000621309.4; ENST00000289779.7
External Link	RMBase: RNA-editing_site_10159
mod ID: A2ISITE000202		Click to Show/Hide the Full List
mod site	chr1:160998099-160998100:-		[4]
Sequence	CACCTGAGGTCAGGAGTTCAAGATCAGCCTGACCAACATGG
Transcript ID List	ENST00000289779.7; ENST00000368026.11; rmsk_283427; ENST00000621309.4
External Link	RMBase: RNA-editing_site_10160
mod ID: A2ISITE000203		Click to Show/Hide the Full List
mod site	chr1:160998100-160998101:-		[4]
Sequence	TCACCTGAGGTCAGGAGTTCAAGATCAGCCTGACCAACATG
Transcript ID List	ENST00000368026.11; ENST00000289779.7; ENST00000621309.4; rmsk_283427
External Link	RMBase: RNA-editing_site_10161
mod ID: A2ISITE000205		Click to Show/Hide the Full List
mod site	chr1:160998108-160998109:-		[4]
Sequence	CAGGCGGATCACCTGAGGTCAGGAGTTCAAGATCAGCCTGA
Transcript ID List	ENST00000621309.4; ENST00000289779.7; rmsk_283427; ENST00000368026.11
External Link	RMBase: RNA-editing_site_10162
mod ID: A2ISITE000208		Click to Show/Hide the Full List
mod site	chr1:160998127-160998128:-		[4]
Sequence	ATAATCCCAGAGGCTGAGGCAGGCGGATCACCTGAGGTCAG
Transcript ID List	ENST00000621309.4; rmsk_283427; ENST00000289779.7; ENST00000368026.11
External Link	RMBase: RNA-editing_site_10163
mod ID: A2ISITE000219		Click to Show/Hide the Full List
mod site	chr1:160998147-160998148:-		[4]
Sequence	GGGCGCAGTGGCTCACGCCTATAATCCCAGAGGCTGAGGCA
Transcript ID List	ENST00000368026.11; ENST00000289779.7; ENST00000621309.4; rmsk_283427
External Link	RMBase: RNA-editing_site_10164
mod ID: A2ISITE000220		Click to Show/Hide the Full List
mod site	chr1:161012390-161012391:-		[2]
Sequence	GTCTTGAACTCCTGGGCTCAAGTGATTCTCCCATCTTGGCC
Transcript ID List	ENST00000602966.1; ENST00000537746.1; ENST00000621309.4; ENST00000335772.3; ENST00000368026.11; ENST00000470694.1; ENST00000289779.7
External Link	RMBase: RNA-editing_site_10165
mod ID: A2ISITE000221		Click to Show/Hide the Full List
mod site	chr1:161021084-161021085:-		[4]
Sequence	TCGGCGGCTGTTGTGTCGGGAGCCTGATCGCGATGGGGACA
Transcript ID List	ENST00000368026.11; ENST00000621309.4; ENST00000470694.1; ENST00000289779.7; ENST00000537746.1; ENST00000602966.1; ENST00000335772.3
External Link	RMBase: RNA-editing_site_10166

5-methylcytidine (m5C)

In total 2 m6A sequence/site(s) in this target gene
mod ID: M5CSITE004242		Click to Show/Hide the Full List
mod site	chr1:160997320-160997321:-		[7]
Sequence	CTACTGTCCCAGAGCTGAGGCAAGGGGATTTCTCAGGTCAT
Cell/Tissue List	frontalcortex; heart; liver; lung; spleen; testis; HeLa; T24
Seq Type List	Bisulfite-seq; m5C-RIP-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: m5C_site_4064
mod ID: M5CSITE004243		Click to Show/Hide the Full List
mod site	chr1:160997988-160997989:-
Sequence	GCCTGGCAACAAGAGCAAAACTCCAGCTCAAAAAAAAAAAG
Cell/Tissue List	liver
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000289779.7; ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m5C_site_4065

N6-methyladenosine (m6A)

In total 52 m6A sequence/site(s) in this target gene
mod ID: M6ASITE062324		Click to Show/Hide the Full List
mod site	chr1:160996199-160996200:-		[8]
Sequence	TATAATAAATGTTTATTTTCACATTGAGTTTGTTTAAATCC
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60793
mod ID: M6ASITE062325		Click to Show/Hide the Full List
mod site	chr1:160996261-160996262:-		[9]
Sequence	TGGACCTTTTGAACTGGAAAACACCTTGTCTGCATTCACTT
Motif Score	2.20572619
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: m6A_site_60794
mod ID: M6ASITE062326		Click to Show/Hide the Full List
mod site	chr1:160996269-160996270:-		[9]
Sequence	GCTTACAATGGACCTTTTGAACTGGAAAACACCTTGTCTGC
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60795
mod ID: M6ASITE062327		Click to Show/Hide the Full List
mod site	chr1:160996278-160996279:-		[9]
Sequence	ACTTCTCTAGCTTACAATGGACCTTTTGAACTGGAAAACAC
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60796
mod ID: M6ASITE062328		Click to Show/Hide the Full List
mod site	chr1:160996285-160996286:-		[10]
Sequence	GGAATTTACTTCTCTAGCTTACAATGGACCTTTTGAACTGG
Motif Score	2.07285119
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60797
mod ID: M6ASITE062329		Click to Show/Hide the Full List
mod site	chr1:160996298-160996299:-		[10]
Sequence	TATTGCCAGCCTTGGAATTTACTTCTCTAGCTTACAATGGA
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60798
mod ID: M6ASITE062330		Click to Show/Hide the Full List
mod site	chr1:160996341-160996342:-		[10]
Sequence	GGTTCCTTATTGTCTAGGCCACTTGTGAAGAATATGAGTCA
Motif Score	2.475107143
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60799
mod ID: M6ASITE062331		Click to Show/Hide the Full List
mod site	chr1:160996435-160996436:-		[9]
Sequence	TTCTGTGTCATGGTTGGAAGACAGAGTAGGAAGGATATGGA
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60800
mod ID: M6ASITE062337		Click to Show/Hide the Full List
mod site	chr1:160996843-160996844:-		[9]
Sequence	AAGAAATGAAATCCAACTAGACAAATAAAGTAGAGCTTATG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60801
mod ID: M6ASITE062348		Click to Show/Hide the Full List
mod site	chr1:160996879-160996880:-		[9]
Sequence	CAAGGGTCACATGCCAATAAACAATAAATTTTCCAGAAGAA
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60802
mod ID: M6ASITE062359		Click to Show/Hide the Full List
mod site	chr1:160996924-160996925:-		[9]
Sequence	TTAAGGATCCAAAAAGAAAAACAAAATGCTAATGAAGCCAT
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60803
mod ID: M6ASITE062370		Click to Show/Hide the Full List
mod site	chr1:160996992-160996993:-		[10]
Sequence	TGGAGGATATACTAAGTGCGACTTTGCCCTATCCTATTTGG
Motif Score	3.287565476
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: m6A_site_60804
mod ID: M6ASITE062375		Click to Show/Hide the Full List
mod site	chr1:160997002-160997003:-		[10]
Sequence	TTTCTTTCTGTGGAGGATATACTAAGTGCGACTTTGCCCTA
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60805
mod ID: M6ASITE062383		Click to Show/Hide the Full List
mod site	chr1:160997057-160997058:-		[8]
Sequence	TTTATTAACTTAGCAAGAGGACAAGTAAAGGGCCCTCTTGG
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60806
mod ID: M6ASITE062387		Click to Show/Hide the Full List
mod site	chr1:160997116-160997117:-		[8]
Sequence	TTGGACCCTTCTCTGCCCTTACATTTTTGTTTCTCCATCTA
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60807
mod ID: M6ASITE062388		Click to Show/Hide the Full List
mod site	chr1:160997292-160997293:-		[8]
Sequence	TTTCTCAGGTCATTTGGAGAACAAGTGCTTTAGTAGTAGTT
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: m6A_site_60808
mod ID: M6ASITE062389		Click to Show/Hide the Full List
mod site	chr1:160997338-160997339:-		[10]
Sequence	TCCCTACAGCTGTAGGAACTACTGTCCCAGAGCTGAGGCAA
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60809
mod ID: M6ASITE062390		Click to Show/Hide the Full List
mod site	chr1:160997398-160997399:-		[10]
Sequence	CCAAGTGAGAGAAGGTACTTACTCTTGTACCTCCTGTTCAG
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: m6A_site_60810
mod ID: M6ASITE062391		Click to Show/Hide the Full List
mod site	chr1:160997469-160997470:-		[8]
Sequence	TTCCTTTGCTGGAGGAAGGTACACAGGGTGAAGCTGATGCT
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60811
mod ID: M6ASITE062392		Click to Show/Hide the Full List
mod site	chr1:160997597-160997598:-		[10]
Sequence	CAAAGCCTTGCTTCCCAGCAACCTGGGGCTGGTTCCCAGTG
Motif Score	2.153267857
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60812
mod ID: M6ASITE062393		Click to Show/Hide the Full List
mod site	chr1:160997634-160997635:-		[10]
Sequence	GGGTTCCTAGGCTCCTTTGTACAACAGGAAAATGCCTCAAA
Motif Score	2.856142857
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: m6A_site_60813
mod ID: M6ASITE062394		Click to Show/Hide the Full List
mod site	chr1:160997904-160997905:-		[9]
Sequence	CCCTTGGCTGGAACTACTGGACAGACCCTTTTGAGATGTGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; MM6; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60814
mod ID: M6ASITE062395		Click to Show/Hide the Full List
mod site	chr1:160997912-160997913:-		[9]
Sequence	TCACCCTTCCCTTGGCTGGAACTACTGGACAGACCCTTTTG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; MM6; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4
External Link	RMBase: m6A_site_60815
mod ID: M6ASITE062396		Click to Show/Hide the Full List
mod site	chr1:160997989-160997990:-		[9]
Sequence	AGCCTGGCAACAAGAGCAAAACTCCAGCTCAAAAAAAAAAA
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; H1A; MM6; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4; ENST00000289779.7
External Link	RMBase: m6A_site_60816
mod ID: M6ASITE062397		Click to Show/Hide the Full List
mod site	chr1:160998000-160998001:-		[8]
Sequence	AGCTGCTCAGGAGCCTGGCAACAAGAGCAAAACTCCAGCTC
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000368026.11; ENST00000289779.7; ENST00000621309.4
External Link	RMBase: m6A_site_60817
mod ID: M6ASITE062398		Click to Show/Hide the Full List
mod site	chr1:160998074-160998075:-		[11]
Sequence	AGCCTGACCAACATGGAGAAACCCTACTAAAAATACAAAGT
Motif Score	2.185083333
Cell/Tissue List	A549; Huh7; TREX; TIME
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_283427; ENST00000368026.11; ENST00000621309.4; ENST00000289779.7
External Link	RMBase: m6A_site_60818
mod ID: M6ASITE062399		Click to Show/Hide the Full List
mod site	chr1:160998177-160998178:-		[9]
Sequence	GCTGCTCTAAAGAAAAGAAAACTGGAGGCTGGGCGCAGTGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; HEK293A-TOA; iSLK; TIME; TREX; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000621309.4; ENST00000289779.7; ENST00000368026.11
External Link	RMBase: m6A_site_60819
mod ID: M6ASITE062400		Click to Show/Hide the Full List
mod site	chr1:160998200-160998201:-		[9]
Sequence	TGAAGCCAAAAGGATTTAAAACCGCTGCTCTAAAGAAAAGA
Motif Score	2.185083333
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; HEK293A-TOA; iSLK; TIME; TREX; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; DART-seq
Transcript ID List	ENST00000289779.7; ENST00000368026.11; ENST00000621309.4
External Link	RMBase: m6A_site_60820
mod ID: M6ASITE062401		Click to Show/Hide the Full List
mod site	chr1:160998223-160998224:-		[9]
Sequence	GCATAGTAAATTTTCAGAGAACTTGAAGCCAAAAGGATTTA
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; HEK293A-TOA; iSLK; TIME; TREX; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; DART-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4; ENST00000289779.7
External Link	RMBase: m6A_site_60821
mod ID: M6ASITE062402		Click to Show/Hide the Full List
mod site	chr1:160998287-160998288:-		[8]
Sequence	TCCTGAATACAAGCTGACTGACATTGACTGTGTCTGTGGAA
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T; A549
Seq Type List	MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000621309.4; ENST00000289779.7; ENST00000368026.11
External Link	RMBase: m6A_site_60822
mod ID: M6ASITE062403		Click to Show/Hide the Full List
mod site	chr1:160998291-160998292:-		[12]
Sequence	GTCCTCCTGAATACAAGCTGACTGACATTGACTGTGTCTGT
Motif Score	3.28175
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000621309.4; ENST00000289779.7; ENST00000368026.11
External Link	RMBase: m6A_site_60823
mod ID: M6ASITE062404		Click to Show/Hide the Full List
mod site	chr1:160998299-160998300:-		[10]
Sequence	TCTGCCCTGTCCTCCTGAATACAAGCTGACTGACATTGACT
Motif Score	2.110482143
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000289779.7; ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60824
mod ID: M6ASITE062405		Click to Show/Hide the Full List
mod site	chr1:160998389-160998390:-		[10]
Sequence	GAAATGGTTGTTTGGTGATGACACTGGGGTCCTTCCATCTC
Motif Score	2.859755952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000621309.4; ENST00000289779.7; ENST00000368026.11
External Link	RMBase: m6A_site_60825
mod ID: M6ASITE062406		Click to Show/Hide the Full List
mod site	chr1:160998525-160998526:-		[10]
Sequence	GAATCTGCACTCAACTGCCCACCTGGCTGGCAGGGATCTTT
Motif Score	2.032470238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000289779.7; ENST00000537746.1; ENST00000368026.11; ENST00000621309.4
External Link	RMBase: m6A_site_60826
mod ID: M6ASITE062407		Click to Show/Hide the Full List
mod site	chr1:160998570-160998571:-		[9]
Sequence	TTGACTTCCCTTCTAAGTAGACAGCAAAAATGGCGGGGGTC
Motif Score	2.897386905
Cell/Tissue List	HeLa; liver
Seq Type List	m6A-seq; m6A-REF-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4; ENST00000289779.7; ENST00000537746.1
External Link	RMBase: m6A_site_60827
mod ID: M6ASITE062408		Click to Show/Hide the Full List
mod site	chr1:160998587-160998588:-		[10]
Sequence	GAATCCTGGGTATGCCATTGACTTCCCTTCTAAGTAGACAG
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000537746.1; ENST00000289779.7; ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60828
mod ID: M6ASITE062409		Click to Show/Hide the Full List
mod site	chr1:160998653-160998654:-		[9]
Sequence	CCACTGCTGAGTGGCCTGGAACTTGTTTAAAGTGTTTATTC
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4; ENST00000289779.7; ENST00000537746.1
External Link	RMBase: m6A_site_60829
mod ID: M6ASITE062410		Click to Show/Hide the Full List
mod site	chr1:160998746-160998747:-		[10]
Sequence	TACACCCCACAGGGCCCCCTACTTCTTCGGATGTGTTTTTA
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000537746.1; ENST00000289779.7; ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60830
mod ID: M6ASITE062411		Click to Show/Hide the Full List
mod site	chr1:160998765-160998766:-		[10]
Sequence	GGATGCCTTATTTGTCTTCTACACCCCACAGGGCCCCCTAC
Motif Score	2.078666667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000289779.7; ENST00000537746.1; ENST00000621309.4; ENST00000368026.11
External Link	RMBase: m6A_site_60831
mod ID: M6ASITE062412		Click to Show/Hide the Full List
mod site	chr1:160998815-160998816:-		[9]
Sequence	CCTTACTCAGGTGCTACCGGACTCTGGCCCCTGATGTCTGT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; A549; HEC-1-A
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000289779.7; ENST00000368026.11; ENST00000621309.4; ENST00000537746.1
External Link	RMBase: m6A_site_60832
mod ID: M6ASITE062413		Click to Show/Hide the Full List
mod site	chr1:160998831-160998832:-		[10]
Sequence	CTATCATCTGCATTTGCCTTACTCAGGTGCTACCGGACTCT
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000621309.4; ENST00000289779.7; ENST00000368026.11; ENST00000537746.1
External Link	RMBase: m6A_site_60833
mod ID: M6ASITE062414		Click to Show/Hide the Full List
mod site	chr1:160998890-160998891:-		[13]
Sequence	TGCAGGGAGAATTCAAACAGACCTCGTCATTCCTGGTGTGA
Motif Score	2.876744048
Cell/Tissue List	A549
Seq Type List	m6A-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4; ENST00000289779.7; ENST00000537746.1
External Link	RMBase: m6A_site_60834
mod ID: M6ASITE062415		Click to Show/Hide the Full List
mod site	chr1:160999641-160999642:-		[14]
Sequence	CTATAGCCGAGGCCACTTTGACAGTAAGTATCTGCCCCCAG
Motif Score	2.859755952
Cell/Tissue List	kidney; liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000289779.7; ENST00000537746.1; ENST00000368026.11; ENST00000621309.4
External Link	RMBase: m6A_site_60835
mod ID: M6ASITE062416		Click to Show/Hide the Full List
mod site	chr1:161000159-161000160:-		[8]
Sequence	CTTCCTATGTCCTGAATCCCACAACAGGAGAGCTGGTATGT
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000472573.5; ENST00000537746.1; ENST00000621309.4; ENST00000368026.11; ENST00000289779.7; ENST00000470694.1
External Link	RMBase: m6A_site_60836
mod ID: M6ASITE062417		Click to Show/Hide the Full List
mod site	chr1:161000245-161000246:-		[8]
Sequence	TGGTTCCCCACCTTCTGAATACACCTGGTTCAAAGATGGGA
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000621309.4; ENST00000470694.1; ENST00000289779.7; ENST00000368026.11; ENST00000472573.5; ENST00000537746.1
External Link	RMBase: m6A_site_60837
mod ID: M6ASITE062418		Click to Show/Hide the Full List
mod site	chr1:161000282-161000283:-		[8]
Sequence	TTGGGAACCGGGCAGTGCTGACATGCTCAGAACAAGATGGT
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000537746.1; ENST00000368026.11; ENST00000470694.1; ENST00000289779.7; ENST00000621309.4; ENST00000472573.5
External Link	RMBase: m6A_site_60838
mod ID: M6ASITE062419		Click to Show/Hide the Full List
mod site	chr1:161000323-161000324:-		[8]
Sequence	TCCATCCAAGCCTACAGTTAACATCCCCTCCTCTGCCACCA
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000472573.5; ENST00000335772.3; ENST00000470694.1; ENST00000537746.1; ENST00000368026.11; ENST00000289779.7; ENST00000621309.4
External Link	RMBase: m6A_site_60839
mod ID: M6ASITE062420		Click to Show/Hide the Full List
mod site	chr1:161000702-161000703:-		[9]
Sequence	TGACACGGGAAGACACTGGGACATACACTTGTATGGTCTCT
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000289779.7; ENST00000621309.4; ENST00000472573.5; ENST00000537746.1; ENST00000470694.1; ENST00000335772.3; ENST00000368026.11
External Link	RMBase: m6A_site_60840
mod ID: M6ASITE062421		Click to Show/Hide the Full List
mod site	chr1:161000710-161000711:-		[9]
Sequence	CAAGTCCGTGACACGGGAAGACACTGGGACATACACTTGTA
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000368026.11; ENST00000621309.4; ENST00000537746.1; ENST00000470694.1; ENST00000289779.7; ENST00000335772.3; ENST00000472573.5
External Link	RMBase: m6A_site_60841
mod ID: M6ASITE062422		Click to Show/Hide the Full List
mod site	chr1:161000720-161000721:-		[8]
Sequence	GTATCACCTTCAAGTCCGTGACACGGGAAGACACTGGGACA
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000602966.1; ENST00000472573.5; ENST00000621309.4; ENST00000335772.3; ENST00000289779.7; ENST00000470694.1; ENST00000537746.1; ENST00000368026.11
External Link	RMBase: m6A_site_60842
mod ID: M6ASITE062423		Click to Show/Hide the Full List
mod site	chr1:161021043-161021044:-		[15]
Sequence	AAGGCGCAAGTCGAGAGGAAACTGTTGTGCCTCTTCATATT
Motif Score	2.627720238
Cell/Tissue List	TIME; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000602966.1; ENST00000335772.3; ENST00000368026.11; ENST00000470694.1; ENST00000537746.1; ENST00000289779.7; ENST00000621309.4
External Link	RMBase: m6A_site_60843
mod ID: M6ASITE062424		Click to Show/Hide the Full List
mod site	chr1:161021066-161021067:-		[15]
Sequence	GGAGCCTGATCGCGATGGGGACAAAGGCGCAAGTCGAGAGG
Motif Score	3.643047619
Cell/Tissue List	TIME
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000335772.3; ENST00000368026.11; ENST00000621309.4; ENST00000289779.7; ENST00000602966.1; ENST00000537746.1; ENST00000470694.1
External Link	RMBase: m6A_site_60844

Ref 1	NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells. Nucleic Acids Res. 2023 Sep 8;51(16):8514-8531. doi: 10.1093/nar/gkad628.
Ref 2	Accurate identification of A-to-I RNA editing in human by transcriptome sequencing. Genome Res. 2012 Jan;22(1):142-50. doi: 10.1101/gr.124107.111. Epub 2011 Sep 29.
Ref 3	Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat Biotechnol. 2012 Feb 12;30(3):253-60. doi: 10.1038/nbt.2122.
Ref 4	Widespread RNA editing of embedded alu elements in the human transcriptome. Genome Res. 2004 Sep;14(9):1719-25. doi: 10.1101/gr.2855504.
Ref 5	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 6	Systematic identification of abundant A-to-I editing sites in the human transcriptome. Nat Biotechnol. 2004 Aug;22(8):1001-5. doi: 10.1038/nbt996. Epub 2004 Jul 18.
Ref 7	Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6784-6789. doi: 10.1073/pnas.1817334116. Epub 2019 Mar 14.
Ref 8	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 9	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 10	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 11	Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nat Commun. 2019 Oct 9;10(1):4595. doi: 10.1038/s41467-019-12504-y.
Ref 12	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 13	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 14	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 15	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.

Epigenetic Target Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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