Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00035)

Target Name	Hepatoma-derived growth factor (HDGF)
Synonyms	HDGF; High mobility group protein 1-like 2; HMG-1L2; HMG1L2 Click to Show/Hide
Gene Name	HDGF
Sequence	MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL Click to Show/Hide
Family	HDGF family
Function	[Isoform 1]: Acts as a transcriptional repressor. Has mitogenic activity for fibroblasts. Heparin-binding protein. [Isoform 2]: Does not have mitogenic activity for fibroblasts. Does not bind heparin. [Isoform 3]: Has mitogenic activity for fibroblasts. Heparin-binding protein. Click to Show/Hide
Gene ID	3068
HGNC ID	HGNC:4856
Ensembl Gene ID	ENSG00000143321
KEGG ID	hsa:3068
Chromosomal Location	1q23.1

RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00035)

Hepatoma-derived growth factor (HDGF)

2'-O-Methylation (2'-O-Me)

In total 5 m6A sequence/site(s) in this target gene
mod ID: 2OMSITE000281		Click to Show/Hide the Full List
mod site	chr1:156743862-156743863:-		[1]
Sequence	CCTAGGACTCTCCTAAACGTCCCAAGGAGGCAGAAAACCCT
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000537739.5; ENST00000477306.1; ENST00000465180.5; ENST00000357325.10; ENST00000482651.5; ENST00000471377.5; ENST00000495212.1; ENST00000368206.5; ENST00000368209.9; ENST00000469145.5
External Link	RMBase: Nm_site_399
mod ID: 2OMSITE000283		Click to Show/Hide the Full List
mod site	chr1:156743864-156743865:-		[1]
Sequence	TGCCTAGGACTCTCCTAAACGTCCCAAGGAGGCAGAAAACC
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000357325.10; ENST00000495212.1; ENST00000368206.5; ENST00000482651.5; ENST00000469145.5; ENST00000477306.1; ENST00000537739.5; ENST00000471377.5; ENST00000465180.5; ENST00000368209.9
External Link	RMBase: Nm_site_401
mod ID: 2OMSITE000279		Click to Show/Hide the Full List
mod site	chr1:156742188-156742189:-		[1]
Sequence	CTTGGGCTCTGATGAAAAATTGCTGACTGTAGCTTTGGAAG
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000368209.9; ENST00000537739.5; ENST00000357325.10
External Link	RMBase: Nm_site_397
mod ID: 2OMSITE000280		Click to Show/Hide the Full List
mod site	chr1:156742733-156742734:-		[1]
Sequence	CTGAGACCTGAAGGGTTGACTTTACCCATTTGGGTGGGAGT
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000465180.5; ENST00000537739.5; ENST00000357325.10; ENST00000368209.9
External Link	RMBase: Nm_site_398
mod ID: 2OMSITE000282		Click to Show/Hide the Full List
mod site	chr1:156743863-156743864:-		[1]
Sequence	GCCTAGGACTCTCCTAAACGTCCCAAGGAGGCAGAAAACCC
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000477306.1; ENST00000368209.9; ENST00000465180.5; ENST00000357325.10; ENST00000537739.5; ENST00000469145.5; ENST00000471377.5; ENST00000482651.5; ENST00000368206.5; ENST00000495212.1
External Link	RMBase: Nm_site_400

5-methylcytidine (m5C)

In total 8 m6A sequence/site(s) in this target gene
mod ID: M5CSITE004198		Click to Show/Hide the Full List
mod site	chr1:156742963-156742964:-		[2]
Sequence	GGGCAGCACAGGAGGGCGGCCTCCTTCTGAGCTCCTGTCCC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000465180.5; ENST00000537739.5
External Link	RMBase: m5C_site_4010
mod ID: M5CSITE004199		Click to Show/Hide the Full List
mod site	chr1:156743365-156743366:-		[3]
Sequence	AACTGGCCATGGCCTGCAAACTGGGAACCCCTTTCCCACCC
Cell/Tissue List	HEK293T; HeLa; T24
Seq Type List	Bisulfite-seq; m5C-RIP-seq
Transcript ID List	ENST00000465180.5; ENST00000368209.9; ENST00000477306.1; ENST00000357325.10; ENST00000537739.5; ENST00000482651.5; ENST00000368206.5
External Link	RMBase: m5C_site_4011
mod ID: M5CSITE004200		Click to Show/Hide the Full List
mod site	chr1:156744157-156744158:-		[2]
Sequence	AGGGGACTTGCTGGAGGTAACTGCTGCCTGCCCAGGGCCTG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000368209.9; ENST00000495212.1; ENST00000471377.5; ENST00000465180.5; ENST00000537739.5; ENST00000477306.1; ENST00000482651.5; ENST00000368206.5; ENST00000357325.10; ENST00000469145.5
External Link	RMBase: m5C_site_4012
mod ID: M5CSITE004201		Click to Show/Hide the Full List
mod site	chr1:156745104-156745105:-		[2]
Sequence	CCTCTTCCCTTACGAGGAATCCAAGGAGAAGTTTGGCAAGC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000495212.1; ENST00000537739.5; ENST00000368206.5; ENST00000469145.5; ENST00000471377.5; ENST00000357325.10; ENST00000465180.5; ENST00000368209.9; ENST00000482651.5
External Link	RMBase: m5C_site_4013
mod ID: M5CSITE004202		Click to Show/Hide the Full List
mod site	chr1:156751433-156751434:-		[3]
Sequence	AGCCCGGGGCGCCCGGAGCCCCGCCATGTCGCGATCCAACC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000537739.5; ENST00000357325.10; ENST00000495212.1; ENST00000469145.5; ENST00000465180.5; ENST00000368206.5; ENST00000471377.5; ENST00000368209.9
External Link	RMBase: m5C_site_4014
mod ID: M5CSITE004203		Click to Show/Hide the Full List
mod site	chr1:156751434-156751435:-		[3]
Sequence	GAGCCCGGGGCGCCCGGAGCCCCGCCATGTCGCGATCCAAC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000471377.5; ENST00000537739.5; ENST00000465180.5; ENST00000368209.9; ENST00000495212.1; ENST00000357325.10; ENST00000469145.5; ENST00000368206.5
External Link	RMBase: m5C_site_4015
mod ID: M5CSITE004204		Click to Show/Hide the Full List
mod site	chr1:156751435-156751436:-		[3]
Sequence	GGAGCCCGGGGCGCCCGGAGCCCCGCCATGTCGCGATCCAA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000368206.5; ENST00000471377.5; ENST00000469145.5; ENST00000495212.1; ENST00000465180.5; ENST00000537739.5
External Link	RMBase: m5C_site_4016
mod ID: M5CSITE004205		Click to Show/Hide the Full List
mod site	chr1:156751444-156751445:-		[3]
Sequence	GCCCGGCGCGGAGCCCGGGGCGCCCGGAGCCCCGCCATGTC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000357325.10; ENST00000465180.5; ENST00000537739.5; ENST00000495212.1; ENST00000368206.5; ENST00000469145.5; ENST00000471377.5; ENST00000368209.9
External Link	RMBase: m5C_site_4017

N6-methyladenosine (m6A)

In total 52 m6A sequence/site(s) in this target gene
mod ID: M6ASITE061011		Click to Show/Hide the Full List
mod site	chr1:156742122-156742123:-		[4]
Sequence	TTCAGTTCTAGGAAAATAAAACCCGTTGATTACTATATTGG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000537739.5; ENST00000368209.9; ENST00000357325.10
External Link	RMBase: m6A_site_59031
mod ID: M6ASITE061022		Click to Show/Hide the Full List
mod site	chr1:156742154-156742155:-		[4]
Sequence	TTGGAAGTTTAGCTCTGAGAACCGTAGATGATTTCAGTTCT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59032
mod ID: M6ASITE061033		Click to Show/Hide the Full List
mod site	chr1:156742183-156742184:-		[5]
Sequence	GCTCTGATGAAAAATTGCTGACTGTAGCTTTGGAAGTTTAG
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000357325.10; ENST00000537739.5; ENST00000368209.9
External Link	RMBase: m6A_site_59033
mod ID: M6ASITE061044		Click to Show/Hide the Full List
mod site	chr1:156742300-156742301:-		[4]
Sequence	ATTTGTAACCCACTGAGAGGACAGAGAGAAATAAGTGCCCT
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59034
mod ID: M6ASITE061055		Click to Show/Hide the Full List
mod site	chr1:156742362-156742363:-		[5]
Sequence	TCCAGTGTCATTTCTCATCCACATACCCTGACCTGGCCCCC
Motif Score	2.053113095
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000357325.10; ENST00000537739.5; ENST00000368209.9
External Link	RMBase: m6A_site_59035
mod ID: M6ASITE061066		Click to Show/Hide the Full List
mod site	chr1:156742416-156742417:-		[5]
Sequence	CTTCTATTTGGGGCTTGATGACTTTCTTTTTGTAGCTGGGG
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000368209.9; ENST00000537739.5; ENST00000357325.10
External Link	RMBase: m6A_site_59036
mod ID: M6ASITE061077		Click to Show/Hide the Full List
mod site	chr1:156742535-156742536:-		[5]
Sequence	GTTTTTAATAAAAGAAAATTACAAAAAAAAATTTTAAAGAC
Motif Score	2.07285119
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000465180.5; ENST00000357325.10; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59037
mod ID: M6ASITE061086		Click to Show/Hide the Full List
mod site	chr1:156742571-156742572:-		[5]
Sequence	CCAGACATAAAGGAAAAGACACATTTTTTAGGAAATGTTTT
Motif Score	2.084928571
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000537739.5; ENST00000465180.5; ENST00000357325.10; ENST00000368209.9
External Link	RMBase: m6A_site_59038
mod ID: M6ASITE061087		Click to Show/Hide the Full List
mod site	chr1:156742573-156742574:-		[5]
Sequence	ACCCAGACATAAAGGAAAAGACACATTTTTTAGGAAATGTT
Motif Score	2.897386905
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000537739.5; ENST00000368209.9; ENST00000357325.10; ENST00000465180.5
External Link	RMBase: m6A_site_59039
mod ID: M6ASITE061088		Click to Show/Hide the Full List
mod site	chr1:156742587-156742588:-		[5]
Sequence	TAGTCATATATATCACCCAGACATAAAGGAAAAGACACATT
Motif Score	2.897386905
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000465180.5; ENST00000368209.9; ENST00000537739.5; ENST00000357325.10
External Link	RMBase: m6A_site_59040
mod ID: M6ASITE061089		Click to Show/Hide the Full List
mod site	chr1:156742630-156742631:-		[5]
Sequence	AGCTGTCCTTTTTCCTCTCCACACAGTGCTCAAGGCCAGCT
Motif Score	2.053113095
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000368209.9; ENST00000465180.5; ENST00000357325.10; ENST00000537739.5
External Link	RMBase: m6A_site_59041
mod ID: M6ASITE061090		Click to Show/Hide the Full List
mod site	chr1:156742677-156742678:-		[6]
Sequence	CCCTTTAGATCTCTGAAGCCACAAATAGGATGCTTGGGAAG
Motif Score	2.053113095
Cell/Tissue List	brain; liver; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000357325.10; ENST00000465180.5; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59042
mod ID: M6ASITE061091		Click to Show/Hide the Full List
mod site	chr1:156742735-156742736:-		[5]
Sequence	ACCTGAGACCTGAAGGGTTGACTTTACCCATTTGGGTGGGA
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000465180.5; ENST00000537739.5
External Link	RMBase: m6A_site_59043
mod ID: M6ASITE061092		Click to Show/Hide the Full List
mod site	chr1:156742848-156742849:-		[7]
Sequence	TAAATCCTTGATGATTGACAACACCCATTTTTCCTTTTGCC
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000537739.5; ENST00000465180.5
External Link	RMBase: m6A_site_59044
mod ID: M6ASITE061093		Click to Show/Hide the Full List
mod site	chr1:156742851-156742852:-		[7]
Sequence	CCATAAATCCTTGATGATTGACAACACCCATTTTTCCTTTT
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000368209.9; ENST00000465180.5; ENST00000537739.5; ENST00000357325.10
External Link	RMBase: m6A_site_59045
mod ID: M6ASITE061094		Click to Show/Hide the Full List
mod site	chr1:156742897-156742898:-		[8]
Sequence	CTAGATTCAGGGAAAGTGGGACAGCTTGTAGGGGAGGGGCT
Motif Score	3.643047619
Cell/Tissue List	HepG2; MT4; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000357325.10; ENST00000465180.5; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59046
mod ID: M6ASITE061095		Click to Show/Hide the Full List
mod site	chr1:156742937-156742938:-		[7]
Sequence	CTGAGCTCCTGTCCCCTGCTACACCTATTATCCCAGCTGCC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000537739.5; ENST00000368209.9; ENST00000357325.10; ENST00000465180.5
External Link	RMBase: m6A_site_59047
mod ID: M6ASITE061096		Click to Show/Hide the Full List
mod site	chr1:156743084-156743085:-		[4]
Sequence	CACTCTCCTAGGCATTCTGGACCTCTGGGTTGGGATCAGGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; H1A; H1B; MT4; A549; peripheral-blood; HEK293T; endometrial; NB4; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000465180.5; ENST00000357325.10; ENST00000537739.5; ENST00000368209.9
External Link	RMBase: m6A_site_59048
mod ID: M6ASITE061097		Click to Show/Hide the Full List
mod site	chr1:156743116-156743117:-		[6]
Sequence	ACAACTGCTCCCACCTCCTGACACCCTTCTCCCACTCTCCT
Motif Score	2.859755952
Cell/Tissue List	kidney; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000537739.5; ENST00000368209.9; ENST00000465180.5; ENST00000357325.10
External Link	RMBase: m6A_site_59049
mod ID: M6ASITE061098		Click to Show/Hide the Full List
mod site	chr1:156743136-156743137:-		[4]
Sequence	GGCTTCTGCTGGGGCCTGGGACAACTGCTCCCACCTCCTGA
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T; HepG2; MT4; peripheral-blood; endometrial; NB4; MM6
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000537739.5; ENST00000465180.5
External Link	RMBase: m6A_site_59050
mod ID: M6ASITE061099		Click to Show/Hide the Full List
mod site	chr1:156743321-156743322:-		[5]
Sequence	CCTGCTCTCCTCTTCTACTCACTTTTCCCACTCCAAGCCCA
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000537739.5; ENST00000368209.9; ENST00000482651.5; ENST00000357325.10; ENST00000477306.1; ENST00000465180.5
External Link	RMBase: m6A_site_59051
mod ID: M6ASITE061100		Click to Show/Hide the Full List
mod site	chr1:156743359-156743360:-		[4]
Sequence	CCATGGCCTGCAAACTGGGAACCCCTTTCCCACCCCAACCT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000477306.1; ENST00000368209.9; ENST00000368206.5; ENST00000482651.5; ENST00000357325.10; ENST00000465180.5; ENST00000537739.5
External Link	RMBase: m6A_site_59052
mod ID: M6ASITE061101		Click to Show/Hide the Full List
mod site	chr1:156743366-156743367:-		[4]
Sequence	AAACTGGCCATGGCCTGCAAACTGGGAACCCCTTTCCCACC
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; A549; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000537739.5; ENST00000465180.5; ENST00000368209.9; ENST00000357325.10; ENST00000477306.1; ENST00000368206.5; ENST00000482651.5
External Link	RMBase: m6A_site_59053
mod ID: M6ASITE061102		Click to Show/Hide the Full List
mod site	chr1:156743384-156743385:-		[4]
Sequence	GTCTGGGTGCTACTGGGGAAACTGGCCATGGCCTGCAAACT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; A549; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000368209.9; ENST00000477306.1; ENST00000357325.10; ENST00000482651.5; ENST00000537739.5; ENST00000465180.5; ENST00000368206.5
External Link	RMBase: m6A_site_59054
mod ID: M6ASITE061103		Click to Show/Hide the Full List
mod site	chr1:156743393-156743394:-		[5]
Sequence	CCTGCTGCTGTCTGGGTGCTACTGGGGAAACTGGCCATGGC
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000477306.1; ENST00000368206.5; ENST00000537739.5; ENST00000465180.5; ENST00000482651.5
External Link	RMBase: m6A_site_59055
mod ID: M6ASITE061104		Click to Show/Hide the Full List
mod site	chr1:156743528-156743529:-		[4]
Sequence	AGGGTGGGCTCTCCTAGGAGACCGGCACTGGCTGGGGCAAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000537739.5; ENST00000465180.5; ENST00000368209.9; ENST00000482651.5; ENST00000368206.5; ENST00000477306.1; ENST00000357325.10
External Link	RMBase: m6A_site_59056
mod ID: M6ASITE061105		Click to Show/Hide the Full List
mod site	chr1:156743608-156743609:-		[4]
Sequence	TGGCAGCTGGACTAGGGGGGACCGGCCACTCTCGGAGAAGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; U2OS; HEK293T; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000368209.9; ENST00000477306.1; ENST00000465180.5; ENST00000482651.5; ENST00000368206.5; ENST00000537739.5; ENST00000357325.10
External Link	RMBase: m6A_site_59057
mod ID: M6ASITE061106		Click to Show/Hide the Full List
mod site	chr1:156743618-156743619:-		[4]
Sequence	CCTGACCCCTTGGCAGCTGGACTAGGGGGGACCGGCCACTC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; U2OS; HEK293T; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000477306.1; ENST00000368209.9; ENST00000368206.5; ENST00000537739.5; ENST00000357325.10; ENST00000465180.5; ENST00000482651.5
External Link	RMBase: m6A_site_59058
mod ID: M6ASITE061107		Click to Show/Hide the Full List
mod site	chr1:156743846-156743847:-		[4]
Sequence	ACGTCCCAAGGAGGCAGAAAACCCTGAAGGAGAGGAGAAGG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; U2OS; H1A; H1B; hNPCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000477306.1; ENST00000368209.9; ENST00000357325.10; ENST00000465180.5; ENST00000469145.5; ENST00000368206.5; ENST00000482651.5; ENST00000471377.5; ENST00000495212.1; ENST00000537739.5
External Link	RMBase: m6A_site_59059
mod ID: M6ASITE061108		Click to Show/Hide the Full List
mod site	chr1:156744172-156744173:-		[4]
Sequence	GTTGAAGAGGAGAGCAGGGGACTTGCTGGAGGTAACTGCTG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; U2OS; H1A; H1B; hNPCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000368209.9; ENST00000471377.5; ENST00000482651.5; ENST00000469145.5; ENST00000465180.5; ENST00000537739.5; ENST00000477306.1; ENST00000357325.10; ENST00000495212.1; ENST00000368206.5
External Link	RMBase: m6A_site_59060
mod ID: M6ASITE061109		Click to Show/Hide the Full List
mod site	chr1:156744250-156744251:-		[5]
Sequence	GAATGCAGAGGGCAGCAGCGACGAGGAAGGGAAGCTGGTCA
Motif Score	2.839505952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000471377.5; ENST00000368206.5; ENST00000368209.9; ENST00000357325.10; ENST00000537739.5; ENST00000495212.1; ENST00000465180.5; ENST00000482651.5; ENST00000477306.1; ENST00000469145.5
External Link	RMBase: m6A_site_59061
mod ID: M6ASITE061110		Click to Show/Hide the Full List
mod site	chr1:156744312-156744313:-		[4]
Sequence	AGCTGTGTGGAAGAGCCTGAACCAGAGCCCGAAGCTGCAGA
Motif Score	2.930744048
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; U2OS; hNPCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000368209.9; ENST00000469145.5; ENST00000482651.5; ENST00000357325.10; ENST00000465180.5; ENST00000537739.5; ENST00000495212.1; ENST00000368206.5; ENST00000471377.5
External Link	RMBase: m6A_site_59062
mod ID: M6ASITE061111		Click to Show/Hide the Full List
mod site	chr1:156745038-156745039:-		[4]
Sequence	GGGGCTGTGGGAGATCGAGAACAACCCTACTGTCAAGGCTT
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD34; HepG2; hESC-HEK293T; U2OS; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000465180.5; ENST00000368209.9; ENST00000482651.5; ENST00000469145.5; ENST00000537739.5; ENST00000471377.5; ENST00000495212.1; ENST00000368206.5; ENST00000357325.10
External Link	RMBase: m6A_site_59063
mod ID: M6ASITE061112		Click to Show/Hide the Full List
mod site	chr1:156745080-156745081:-		[6]
Sequence	GGAGAAGTTTGGCAAGCCCAACAAGAGGAAAGGGTTCAGCG
Motif Score	2.173910714
Cell/Tissue List	brain; kidney; liver; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000368209.9; ENST00000482651.5; ENST00000368206.5; ENST00000495212.1; ENST00000357325.10; ENST00000465180.5; ENST00000469145.5; ENST00000537739.5; ENST00000471377.5
External Link	RMBase: m6A_site_59064
mod ID: M6ASITE061113		Click to Show/Hide the Full List
mod site	chr1:156745125-156745126:-		[4]
Sequence	GGCATTCCTGGGCCCCAAAGACCTCTTCCCTTACGAGGAAT
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; U2OS; A549; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000465180.5; ENST00000537739.5; ENST00000357325.10; ENST00000368206.5; ENST00000482651.5; ENST00000368209.9; ENST00000471377.5; ENST00000495212.1; ENST00000469145.5
External Link	RMBase: m6A_site_59065
mod ID: M6ASITE061114		Click to Show/Hide the Full List
mod site	chr1:156745250-156745251:-		[9]
Sequence	GTCGGGAGGGCCCCGGGAGGACTACTCTGGGGAAGGTGAGG
Motif Score	4.065041667
Cell/Tissue List	A549
Seq Type List	m6A-seq
Transcript ID List	ENST00000482651.5; ENST00000537739.5; ENST00000495212.1; ENST00000368206.5; ENST00000465180.5; ENST00000357325.10; ENST00000368209.9; ENST00000469145.5; ENST00000471377.5
External Link	RMBase: m6A_site_59066
mod ID: M6ASITE061115		Click to Show/Hide the Full List
mod site	chr1:156745306-156745307:-		[10]
Sequence	ACCAAGTCTTTTTTTTCGGGACCCACGAGACGTGAGTGGAG
Motif Score	3.622404762
Cell/Tissue List	MT4; A549; MM6; Huh7
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000368206.5; ENST00000471377.5; ENST00000469145.5; ENST00000357325.10; ENST00000368209.9; ENST00000495212.1; ENST00000482651.5; ENST00000537739.5; ENST00000465180.5
External Link	RMBase: m6A_site_59067
mod ID: M6ASITE061116		Click to Show/Hide the Full List
mod site	chr1:156745332-156745333:-		[7]
Sequence	TGCCGTGAAATCAACAGCCAACAAATACCAAGTCTTTTTTT
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000495212.1; ENST00000465180.5; ENST00000482651.5; ENST00000537739.5; ENST00000357325.10; ENST00000471377.5; ENST00000368206.5; ENST00000469145.5; ENST00000368209.9
External Link	RMBase: m6A_site_59068
mod ID: M6ASITE061117		Click to Show/Hide the Full List
mod site	chr1:156747458-156747459:-		[8]
Sequence	CCCAGGCGTCCTGGCTGAGGACCGACTCCTCTGTCCCTGCT
Motif Score	3.622404762
Cell/Tissue List	HepG2; U2OS; MT4; A549; MM6; Huh7; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000357325.10; ENST00000368209.9; ENST00000465180.5; ENST00000471377.5; ENST00000482651.5; ENST00000368206.5; ENST00000495212.1; ENST00000469145.5; ENST00000537739.5
External Link	RMBase: m6A_site_59069
mod ID: M6ASITE061118		Click to Show/Hide the Full List
mod site	chr1:156751355-156751356:-		[5]
Sequence	CAAGATGAAGGGCTACCCACACTGGCCGGCCCGGGTGAGCA
Motif Score	2.506922619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000471377.5; ENST00000357325.10; ENST00000495212.1; ENST00000368206.5; ENST00000368209.9; ENST00000537739.5; ENST00000469145.5; ENST00000465180.5
External Link	RMBase: m6A_site_59070
mod ID: M6ASITE061119		Click to Show/Hide the Full List
mod site	chr1:156751357-156751358:-		[7]
Sequence	GCCAAGATGAAGGGCTACCCACACTGGCCGGCCCGGGTGAG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000465180.5; ENST00000357325.10; ENST00000469145.5; ENST00000471377.5; ENST00000495212.1; ENST00000368206.5; ENST00000368209.9; ENST00000537739.5
External Link	RMBase: m6A_site_59071
mod ID: M6ASITE061120		Click to Show/Hide the Full List
mod site	chr1:156751388-156751389:-		[11]
Sequence	GAAGGAGTACAAATGCGGGGACCTGGTGTTCGCCAAGATGA
Motif Score	3.622404762
Cell/Tissue List	A549; HepG2; U2OS; MT4; MM6; Huh7; NB4
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000537739.5; ENST00000469145.5; ENST00000368209.9; ENST00000368206.5; ENST00000357325.10; ENST00000471377.5; ENST00000465180.5; ENST00000495212.1
External Link	RMBase: m6A_site_59072
mod ID: M6ASITE061121		Click to Show/Hide the Full List
mod site	chr1:156751400-156751401:-		[7]
Sequence	ATCCAACCGGCAGAAGGAGTACAAATGCGGGGACCTGGTGT
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000495212.1; ENST00000471377.5; ENST00000357325.10; ENST00000368206.5; ENST00000537739.5; ENST00000465180.5; ENST00000368209.9; ENST00000469145.5
External Link	RMBase: m6A_site_59073
mod ID: M6ASITE061122		Click to Show/Hide the Full List
mod site	chr1:156751484-156751485:-		[4]
Sequence	CGCCACCGCCGCACGCGCAAACTTGGGCTCGCGCTTCCCGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; CD34; HepG2; A549; U2OS; MM6; Jurkat; GSC-11; HEK293T; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000357325.10; ENST00000469145.5; ENST00000465180.5; ENST00000537739.5; ENST00000471377.5; ENST00000368206.5; ENST00000368209.9; ENST00000495212.1
External Link	RMBase: m6A_site_59074
mod ID: M6ASITE061123		Click to Show/Hide the Full List
mod site	chr1:156751662-156751663:-		[12]
Sequence	TTGAATTTCAAACACAAACAACTGCACGAGCGCGCACCCAC
Motif Score	2.595904762
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000465180.5; ENST00000368206.5; ENST00000357325.10; ENST00000471377.5; ENST00000368209.9
External Link	RMBase: m6A_site_59075
mod ID: M6ASITE061124		Click to Show/Hide the Full List
mod site	chr1:156751665-156751666:-		[4]
Sequence	CAATTGAATTTCAAACACAAACAACTGCACGAGCGCGCACC
Motif Score	2.20572619
Cell/Tissue List	HeLa; A549; hESC-HEK293T; HepG2; U2OS; H1A; H1B; hESCs; fibroblasts; H1299; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000368206.5; ENST00000465180.5; ENST00000368209.9; ENST00000357325.10; ENST00000471377.5
External Link	RMBase: m6A_site_59076
mod ID: M6ASITE061125		Click to Show/Hide the Full List
mod site	chr1:156751671-156751672:-		[4]
Sequence	AGGGAGCAATTGAATTTCAAACACAAACAACTGCACGAGCG
Motif Score	2.20572619
Cell/Tissue List	HeLa; A549; hESC-HEK293T; HepG2; U2OS; H1A; H1B; hESCs; fibroblasts; H1299; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000368206.5; ENST00000357325.10; ENST00000471377.5; ENST00000465180.5; ENST00000368209.9
External Link	RMBase: m6A_site_59077
mod ID: M6ASITE061126		Click to Show/Hide the Full List
mod site	chr1:156752080-156752081:-		[4]
Sequence	GGAGCAGAGGGCAGGCGGAAACCGTGTACAGACGTCCACAC
Motif Score	2.185083333
Cell/Tissue List	HeLa; A549; HepG2; U2OS; H1A; H1B; hESCs; HEK293T; fibroblasts; H1299; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000368209.9; ENST00000368206.5; ENST00000471377.5; ENST00000465180.5
External Link	RMBase: m6A_site_59078
mod ID: M6ASITE061127		Click to Show/Hide the Full List
mod site	chr1:156752136-156752137:-		[4]
Sequence	CGCCTAGCACGCTGCCAAGAACCGCGGGTGCCCAGTAAATA
Motif Score	2.930744048
Cell/Tissue List	HeLa; A549; H1B; H1A; H1299; peripheral-blood; GSC-11; HEK293A-TOA; MSC; iSLK; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_276152; ENST00000471377.5; ENST00000465180.5; ENST00000368206.5; ENST00000368209.9
External Link	RMBase: m6A_site_59079
mod ID: M6ASITE061128		Click to Show/Hide the Full List
mod site	chr1:156752202-156752203:-		[4]
Sequence	CACGGCGAGGTCCAGAGAGGACCCCAGTGCGCGGAGCGGCA
Motif Score	3.622404762
Cell/Tissue List	HeLa; Huh7; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000471377.5; ENST00000368209.9; ENST00000368206.5; ENST00000465180.5
External Link	RMBase: m6A_site_59080
mod ID: M6ASITE061129		Click to Show/Hide the Full List
mod site	chr1:156752303-156752304:-		[4]
Sequence	GGCCATCTCCTGGCTACCAAACTCAAGCGTTTCCTCCTTAG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000368206.5; ENST00000465180.5
External Link	RMBase: m6A_site_59081
mod ID: M6ASITE061130		Click to Show/Hide the Full List
mod site	chr1:156752388-156752389:-		[4]
Sequence	GTCCAAGTCTCCTTGGCAAGACAGTAGCTTAGAGAAACGAG
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000368206.5; ENST00000465180.5
External Link	RMBase: m6A_site_59082

Ref 1	Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nat Methods. 2017 Jul;14(7):695-698. doi: 10.1038/nmeth.4294. Epub 2017 May 15.
Ref 2	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 3	Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6784-6789. doi: 10.1073/pnas.1817334116. Epub 2019 Mar 14.
Ref 4	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 5	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 6	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 7	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 8	Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature. 2012 Apr 29;485(7397):201-6. doi: 10.1038/nature11112.
Ref 9	The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol Cell. 2016 May 5;62(3):335-345. doi: 10.1016/j.molcel.2016.03.021. Epub 2016 Apr 21.
Ref 10	Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells. Nat Microbiol. 2016 Feb 22;1:16011. doi: 10.1038/nmicrobiol.2016.11.
Ref 11	Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nat Commun. 2019 Oct 9;10(1):4595. doi: 10.1038/s41467-019-12504-y.
Ref 12	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.

Epigenetic Target Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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