Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00014)

Target Name	TINCR ubiquitin domain containing (TINCR)
Synonyms	FLJ90734; NCRNA00036; LINC00036; onco-lncRNA-16; TUBL; PLAC2; placenta-specific 2; placenta-specific 2 (non-protein coding); tissue differentiation-inducing non-protein coding RNA Click to Show/Hide
Gene Name	TINCR
Sequence	MEGLRRGLSRWKRYHIKVHLADEALLLPLTVRPRDTLSDLRAQLVGQGVSSWKRAFYYNARRLDDHQTVRDARLQDGSVLLLVSDPSEAQRLTPAIPALWEAEASRSLESRSSRPAWPTW Click to Show/Hide
Gene ID	257000
HGNC ID	HGNC:14607
Ensembl Gene ID	ENSG00000223573
Chromosomal Location	19p13.3

RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00014)

TINCR ubiquitin domain containing (TINCR)

Adenosine-to-Inosine editing (A-to-I)

In total 18 m6A sequence/site(s) in this target gene
mod ID: A2ISITE008774		Click to Show/Hide the Full List
mod site	chr19:5559396-5559397:-		[1]
Sequence	GGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTG
Transcript ID List	rmsk_4922944; ENST00000448587.5
External Link	RMBase: RNA-editing_site_64902
mod ID: A2ISITE008775		Click to Show/Hide the Full List
mod site	chr19:5559399-5559400:-		[1]
Sequence	AGAGGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGC
Transcript ID List	ENST00000448587.5; rmsk_4922944
External Link	RMBase: RNA-editing_site_64903
mod ID: A2ISITE008776		Click to Show/Hide the Full List
mod site	chr19:5559401-5559402:-		[1]
Sequence	GCAGAGGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCA
Transcript ID List	rmsk_4922944; ENST00000448587.5
External Link	RMBase: RNA-editing_site_64904
mod ID: A2ISITE008777		Click to Show/Hide the Full List
mod site	chr19:5559419-5559420:-		[1]
Sequence	ATGGCGGGAACCCGGGAGGCAGAGGTTGCAGTGAGCTGAGA
Transcript ID List	rmsk_4922944; ENST00000448587.5
External Link	RMBase: RNA-editing_site_64905
mod ID: A2ISITE008778		Click to Show/Hide the Full List
mod site	chr19:5559430-5559431:-		[1]
Sequence	GAGGCAGGAGAATGGCGGGAACCCGGGAGGCAGAGGTTGCA
Transcript ID List	rmsk_4922944; ENST00000448587.5
External Link	RMBase: RNA-editing_site_64906
mod ID: A2ISITE008779		Click to Show/Hide the Full List
mod site	chr19:5559440-5559441:-		[1]
Sequence	TTGGTAGGCTGAGGCAGGAGAATGGCGGGAACCCGGGAGGC
Transcript ID List	ENST00000448587.5; rmsk_4922944
External Link	RMBase: RNA-editing_site_64907
mod ID: A2ISITE008780		Click to Show/Hide the Full List
mod site	chr19:5559462-5559463:-		[1]
Sequence	GGGCGCCTGTAGTCCCAGCTACTTGGTAGGCTGAGGCAGGA
Transcript ID List	ENST00000448587.5; rmsk_4922944
External Link	RMBase: RNA-editing_site_64908
mod ID: A2ISITE008781		Click to Show/Hide the Full List
mod site	chr19:5559466-5559467:-		[1]
Sequence	TGGCGGGCGCCTGTAGTCCCAGCTACTTGGTAGGCTGAGGC
Transcript ID List	ENST00000448587.5; rmsk_4922944
External Link	RMBase: RNA-editing_site_64909
mod ID: A2ISITE008782		Click to Show/Hide the Full List
mod site	chr19:5559472-5559473:-		[1]
Sequence	GCCTGGTGGCGGGCGCCTGTAGTCCCAGCTACTTGGTAGGC
Transcript ID List	ENST00000448587.5; rmsk_4922944
External Link	RMBase: RNA-editing_site_64910
mod ID: A2ISITE008783		Click to Show/Hide the Full List
mod site	chr19:5559498-5559499:-		[1]
Sequence	ACTAAAAGTACAAAAAAAATAGCCGGGCCTGGTGGCGGGCG
Transcript ID List	ENST00000448587.5; rmsk_4922944
External Link	RMBase: RNA-editing_site_64911
mod ID: A2ISITE008784		Click to Show/Hide the Full List
mod site	chr19:5559512-5559513:-		[1]
Sequence	GAAACCCCGTCTCTACTAAAAGTACAAAAAAAATAGCCGGG
Transcript ID List	rmsk_4922944; ENST00000448587.5
External Link	RMBase: RNA-editing_site_64912
mod ID: A2ISITE008785		Click to Show/Hide the Full List
mod site	chr19:5559529-5559530:-		[1]
Sequence	ATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAGTA
Transcript ID List	ENST00000448587.5; rmsk_4922944
External Link	RMBase: RNA-editing_site_64913
mod ID: A2ISITE008786		Click to Show/Hide the Full List
mod site	chr19:5559530-5559531:-		[1]
Sequence	CATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAGT
Transcript ID List	ENST00000448587.5; rmsk_4922944
External Link	RMBase: RNA-editing_site_64914
mod ID: A2ISITE008787		Click to Show/Hide the Full List
mod site	chr19:5559563-5559564:-		[1]
Sequence	GGCAGGCGGATCATGAGGTCAGGAGATGGAGACCATCCTGG
Transcript ID List	ENST00000448587.5; rmsk_4922944
External Link	RMBase: RNA-editing_site_64915
mod ID: A2ISITE008788		Click to Show/Hide the Full List
mod site	chr19:5559606-5559607:-		[1]
Sequence	CGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGAC
Transcript ID List	ENST00000448587.5; rmsk_4922944
External Link	RMBase: RNA-editing_site_64916
mod ID: A2ISITE008789		Click to Show/Hide the Full List
mod site	chr19:5562454-5562455:-		[2]
Sequence	GTAGGTGCTTAATAAATGTTAGTGAGATGTATTGTCTCACT
Transcript ID List	rmsk_4922949; ENST00000587632.1; ENST00000448587.5; ENST00000646675.1
External Link	RMBase: RNA-editing_site_64917
mod ID: A2ISITE008790		Click to Show/Hide the Full List
mod site	chr19:5562541-5562542:-		[2]
Sequence	GTCTCCTGCAGTAGACTGTAAACTCTGTGAGGGTACTGCCG
Transcript ID List	ENST00000646675.1; ENST00000448587.5; rmsk_4922949; ENST00000587632.1
External Link	RMBase: RNA-editing_site_64918
mod ID: A2ISITE008791		Click to Show/Hide the Full List
mod site	chr19:5565051-5565052:-		[2]
Sequence	CCGAGGGAGGTGGGAGCCATAGAGGGCTGTGGGCAGAGGAG
Transcript ID List	ENST00000646160.1; ENST00000587632.1; ENST00000646675.1; ENST00000448587.5
External Link	RMBase: RNA-editing_site_64919

N6-methyladenosine (m6A)

In total 33 m6A sequence/site(s) in this target gene
mod ID: M6ASITE038720		Click to Show/Hide the Full List
mod site	chr19:5558169-5558170:-		[3]
Sequence	AAAAGATTACATGTTTGAAAACAAGATTGAGTTTAAGCTTC
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413339
mod ID: M6ASITE038722		Click to Show/Hide the Full List
mod site	chr19:5558227-5558228:-		[3]
Sequence	GCAGGATCACCCAGCTTGGAACTAGATACAGAAATGCTGTT
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413340
mod ID: M6ASITE038723		Click to Show/Hide the Full List
mod site	chr19:5558298-5558299:-		[3]
Sequence	ACTCACTCGGGATCCACTGAACTGGGAGGTCTGTGTCTCCT
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413341
mod ID: M6ASITE038724		Click to Show/Hide the Full List
mod site	chr19:5558346-5558347:-		[3]
Sequence	AGAGCCTACTTCCCTCAAGGACCCTGCTGCTTCCAGTCTCA
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5; rmsk_4922938
External Link	RMBase: m6A_site_413342
mod ID: M6ASITE038725		Click to Show/Hide the Full List
mod site	chr19:5558619-5558620:-		[3]
Sequence	GCTTGACAGGGCCAAGGGGAACTATTGTGGAATGTCTTGGC
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413343
mod ID: M6ASITE038726		Click to Show/Hide the Full List
mod site	chr19:5558867-5558868:-		[4]
Sequence	CTTCACATCATTTGTCCAAGACCTCCCTGGCCTGAGATAAA
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413344
mod ID: M6ASITE038727		Click to Show/Hide the Full List
mod site	chr19:5559037-5559038:-		[3]
Sequence	TTCTGAAATAATAATGTTGGACCTGTCCCTTGATGATGACC
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413345
mod ID: M6ASITE038728		Click to Show/Hide the Full List
mod site	chr19:5560112-5560113:-		[3]
Sequence	CACTTCACTCCGGCAGGCAGACCTGCTGGAGCTGCTTTGCA
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413346
mod ID: M6ASITE038729		Click to Show/Hide the Full List
mod site	chr19:5560205-5560206:-		[3]
Sequence	CCCTTCAGAGCATCTGCCAAACTTCGGGCATCTACCCTGCA
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413347
mod ID: M6ASITE038730		Click to Show/Hide the Full List
mod site	chr19:5560257-5560258:-		[3]
Sequence	TGCGTTTGCTTAGCTCGGGGACAGCACTTGGCCCGGGGTCT
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413348
mod ID: M6ASITE038731		Click to Show/Hide the Full List
mod site	chr19:5560281-5560282:-		[3]
Sequence	ACGGGGACAGCCGTGCCCAGACTGTGCGTTTGCTTAGCTCG
Motif Score	3.319380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413349
mod ID: M6ASITE038733		Click to Show/Hide the Full List
mod site	chr19:5560295-5560296:-		[3]
Sequence	AGTAAATCACCACCACGGGGACAGCCGTGCCCAGACTGTGC
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413350
mod ID: M6ASITE038734		Click to Show/Hide the Full List
mod site	chr19:5560325-5560326:-		[3]
Sequence	CTGCAGGACTCAGAGCATGGACAGGTGGATAGTAAATCACC
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413351
mod ID: M6ASITE038735		Click to Show/Hide the Full List
mod site	chr19:5560338-5560339:-		[3]
Sequence	AGAGTCCTGTTGGCTGCAGGACTCAGAGCATGGACAGGTGG
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413352
mod ID: M6ASITE038736		Click to Show/Hide the Full List
mod site	chr19:5560546-5560547:-		[3]
Sequence	TGTGGGAATTCCGGGTGGAGACCCTCAGGGCAGTGTGCCGG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; Jurkat
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413353
mod ID: M6ASITE038737		Click to Show/Hide the Full List
mod site	chr19:5560615-5560616:-		[3]
Sequence	CGAGGATCTGGGGGTGGGGAACTGGGCCTAGCTGTGGGAGG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; Jurkat
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413354
mod ID: M6ASITE038738		Click to Show/Hide the Full List
mod site	chr19:5560651-5560652:-		[3]
Sequence	CGGGGAAGGGGTTCTGAAGAACTCTGGCCAAGAGGACGAGG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; Jurkat
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448587.5
External Link	RMBase: m6A_site_413355
mod ID: M6ASITE038739		Click to Show/Hide the Full List
mod site	chr19:5560817-5560818:-		[3]
Sequence	GACTAAGCGGGGAGATGCGGACATCCTAGCTCCTTCTCAGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; Jurkat; HEK293A-TOA; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000646675.1; ENST00000448587.5
External Link	RMBase: m6A_site_413356
mod ID: M6ASITE038740		Click to Show/Hide the Full List
mod site	chr19:5560847-5560848:-		[3]
Sequence	GTGCAGCCAGTCGTGTCCGAACTCTCCAATGACTAAGCGGG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; Jurkat; HEK293A-TOA; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000646675.1; ENST00000448587.5
External Link	RMBase: m6A_site_413357
mod ID: M6ASITE038741		Click to Show/Hide the Full List
mod site	chr19:5560883-5560884:-		[3]
Sequence	ACAGGCCCTTTGTGCAGTGAACAGCCCTGGCTGGGGGTGCA
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; Jurkat; HEK293A-TOA; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000646675.1; ENST00000448587.5
External Link	RMBase: m6A_site_413358
mod ID: M6ASITE038742		Click to Show/Hide the Full List
mod site	chr19:5561069-5561070:-		[3]
Sequence	CACTTCCGCTCTTGCCCAGGACATTTTCCCAGCCACACCTT
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; H1B; H1A; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000646675.1; ENST00000590789.1; ENST00000448587.5
External Link	RMBase: m6A_site_413359
mod ID: M6ASITE038744		Click to Show/Hide the Full List
mod site	chr19:5561100-5561101:-		[3]
Sequence	GCACAGAAGGGGCAGGAGAGACACTCAGAGGCACTTCCGCT
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; H1B; H1A; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448587.5; ENST00000646675.1; ENST00000590789.1
External Link	RMBase: m6A_site_413360
mod ID: M6ASITE038745		Click to Show/Hide the Full List
mod site	chr19:5561296-5561297:-		[3]
Sequence	GTCCCTGACAAGGACCTAGGACATTTTTGCTCCTGCCCAGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; Jurkat; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000646675.1; ENST00000590789.1; ENST00000448587.5
External Link	RMBase: m6A_site_413361
mod ID: M6ASITE038746		Click to Show/Hide the Full List
mod site	chr19:5561303-5561304:-		[3]
Sequence	AGCCCCAGTCCCTGACAAGGACCTAGGACATTTTTGCTCCT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; Jurkat; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448587.5; ENST00000646675.1; ENST00000590789.1
External Link	RMBase: m6A_site_413362
mod ID: M6ASITE038747		Click to Show/Hide the Full List
mod site	chr19:5561336-5561337:-		[3]
Sequence	GCTGATGCACACTGCTTCAGACACTCCTGCTGGAGCCCCAG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; Jurkat; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448587.5; ENST00000646675.1; ENST00000590789.1
External Link	RMBase: m6A_site_413363
mod ID: M6ASITE038748		Click to Show/Hide the Full List
mod site	chr19:5561371-5561372:-		[3]
Sequence	GCTCCCAGGTGGACCATGAAACCCTGGCCTGACCAGCTGAT
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; Jurkat; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000646675.1; ENST00000448587.5; ENST00000590789.1
External Link	RMBase: m6A_site_413364
mod ID: M6ASITE038749		Click to Show/Hide the Full List
mod site	chr19:5561379-5561380:-		[3]
Sequence	GGGTCTGGGCTCCCAGGTGGACCATGAAACCCTGGCCTGAC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; Jurkat; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000590789.1; ENST00000448587.5; ENST00000646675.1
External Link	RMBase: m6A_site_413365
mod ID: M6ASITE038750		Click to Show/Hide the Full List
mod site	chr19:5561697-5561698:-		[3]
Sequence	GTTCCAAGAGAATCGCTTGAACCCAGGAGTCAGAGGTTACA
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2
Seq Type List	m6A-seq
Transcript ID List	rmsk_4922946; ENST00000646675.1; ENST00000448587.5; ENST00000587632.1; ENST00000590789.1
External Link	RMBase: m6A_site_413366
mod ID: M6ASITE038751		Click to Show/Hide the Full List
mod site	chr19:5561725-5561726:-		[3]
Sequence	CTGCCATCAGGTGGCAGAAAACAGCCAAGTTCCAAGAGAAT
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5; ENST00000590789.1; ENST00000587632.1; ENST00000646675.1
External Link	RMBase: m6A_site_413367
mod ID: M6ASITE038752		Click to Show/Hide the Full List
mod site	chr19:5562171-5562172:-		[3]
Sequence	GCAGAGCCATGACCAAGGGGACCTGGGTACTGGCTGAAGGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000587632.1; ENST00000448587.5; ENST00000590789.1; ENST00000646675.1
External Link	RMBase: m6A_site_413368
mod ID: M6ASITE038753		Click to Show/Hide the Full List
mod site	chr19:5567820-5567821:-		[3]
Sequence	GCTGACCGTGCGGCCGCGGGACACGCTCAGCGACCTGCGCG
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448587.5; ENST00000646160.1; ENST00000646675.1; ENST00000587632.1
External Link	RMBase: m6A_site_413369
mod ID: M6ASITE038755		Click to Show/Hide the Full List
mod site	chr19:5576719-5576720:-		[5]
Sequence	AAAACAAAGTCAAGAAAACAACTGGGTCGGATCATGCTAAA
Motif Score	2.595904762
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000435815.1; ENST00000646675.1
External Link	RMBase: m6A_site_413370
mod ID: M6ASITE038756		Click to Show/Hide the Full List
mod site	chr19:5576722-5576723:-		[5]
Sequence	TCTAAAACAAAGTCAAGAAAACAACTGGGTCGGATCATGCT
Motif Score	2.20572619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000435815.1; ENST00000646675.1
External Link	RMBase: m6A_site_413371

Ref 1	Widespread RNA editing of embedded alu elements in the human transcriptome. Genome Res. 2004 Sep;14(9):1719-25. doi: 10.1101/gr.2855504.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 4	N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505(7481):117-20. doi: 10.1038/nature12730. Epub 2013 Nov 27.
Ref 5	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.

Epigenetic Target Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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