Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00001)

Target Name	Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Synonyms	CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1 Click to Show/Hide
Gene Name	CDKN1A
Sequence	MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP Click to Show/Hide
Family	CDI family
Function	May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex. Inhibits DNA synthesis by DNA polymerase delta by competing with POLD3 for PCNA binding. Plays an important role in controlling cell cycle progression and DNA damage-induced G2 arrest. Click to Show/Hide
Gene ID	1026
HGNC ID	HGNC:1784
Ensembl Gene ID	ENSG00000124762
KEGG ID	hsa:1026
Chromosomal Location	6p21.2

RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00001)

Cyclin-dependent kinase inhibitor 1 (CDKN1A)

Adenosine-to-Inosine editing (A-to-I)

In total 6 m6A sequence/site(s) in this target gene
mod ID: A2ISITE001436		Click to Show/Hide the Full List
mod site	chr6:36682188-36682189:+		[1]
Sequence	CTTATGAACTGTGTGATGTTAGGCAAGTTACTTAACTTATC
Transcript ID List	ENST00000405375.5; ENST00000459970.1; ENST00000615513.4; ENST00000244741.9; ENST00000373711.3; ENST00000448526.6; ENST00000478800.1; rmsk_1919667
External Link	RMBase: RNA-editing_site_115776
mod ID: A2ISITE001437		Click to Show/Hide the Full List
mod site	chr6:36682197-36682198:+		[1]
Sequence	TGTGTGATGTTAGGCAAGTTACTTAACTTATCTGAGCCTTG
Transcript ID List	ENST00000615513.4; ENST00000244741.9; ENST00000448526.6; ENST00000459970.1; rmsk_1919667; ENST00000373711.3; ENST00000478800.1; ENST00000405375.5
External Link	RMBase: RNA-editing_site_115777
mod ID: A2ISITE001438		Click to Show/Hide the Full List
mod site	chr6:36682206-36682207:+		[1]
Sequence	TTAGGCAAGTTACTTAACTTATCTGAGCCTTGGTTGCCTCT
Transcript ID List	ENST00000448526.6; ENST00000478800.1; ENST00000459970.1; ENST00000244741.9; ENST00000405375.5; ENST00000615513.4; ENST00000373711.3; rmsk_1919667
External Link	RMBase: RNA-editing_site_115778
mod ID: A2ISITE001439		Click to Show/Hide the Full List
mod site	chr6:36683265-36683266:+		[1]
Sequence	GAGGAAACTAGAGCTCAGACAAGTTAAGTTGCTTGCCCAGG
Transcript ID List	ENST00000373711.3; ENST00000405375.5; ENST00000615513.4; ENST00000478800.1; ENST00000459970.1; ENST00000448526.6; ENST00000244741.9
External Link	RMBase: RNA-editing_site_115779
mod ID: A2ISITE001440		Click to Show/Hide the Full List
mod site	chr6:36683266-36683267:+		[1]
Sequence	AGGAAACTAGAGCTCAGACAAGTTAAGTTGCTTGCCCAGGG
Transcript ID List	ENST00000478800.1; ENST00000459970.1; ENST00000615513.4; ENST00000448526.6; ENST00000244741.9; ENST00000373711.3; ENST00000405375.5
External Link	RMBase: RNA-editing_site_115780
mod ID: A2ISITE001441		Click to Show/Hide the Full List
mod site	chr6:36684876-36684877:+		[1]
Sequence	GTCTTAACTCTGTTGGCCAGACTGGAGTGCAGTGATACGAT
Transcript ID List	ENST00000448526.6; ENST00000373711.3; ENST00000615513.4; ENST00000405375.5; ENST00000244741.9
External Link	RMBase: RNA-editing_site_115781

N6-methyladenosine (m6A)

In total 46 m6A sequence/site(s) in this target gene
mod ID: M6ASITE074863		Click to Show/Hide the Full List
mod site	chr6:36676546-36676547:+		[2]
Sequence	GAGGAAGGGGATGGTAGGAGACAGGAGACCTCTAAAGACCC
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448526.6; ENST00000615513.4; ENST00000459970.1
External Link	RMBase: m6A_site_715130
mod ID: M6ASITE074864		Click to Show/Hide the Full List
mod site	chr6:36676553-36676554:+		[2]
Sequence	GGGATGGTAGGAGACAGGAGACCTCTAAAGACCCCAGGTAA
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000459970.1; ENST00000615513.4; ENST00000448526.6
External Link	RMBase: m6A_site_715131
mod ID: M6ASITE074865		Click to Show/Hide the Full List
mod site	chr6:36676563-36676564:+		[2]
Sequence	GAGACAGGAGACCTCTAAAGACCCCAGGTAAACCTTAGCCT
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000615513.4; ENST00000448526.6; ENST00000459970.1
External Link	RMBase: m6A_site_715132
mod ID: M6ASITE074866		Click to Show/Hide the Full List
mod site	chr6:36677795-36677796:+		[2]
Sequence	GATCTGAGTTAGGTCACCAGACTTCTCTGAGCCCCAGTTTC
Motif Score	3.319380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000459970.1; rmsk_1919658; ENST00000448526.6; ENST00000615513.4
External Link	RMBase: m6A_site_715133
mod ID: M6ASITE074867		Click to Show/Hide the Full List
mod site	chr6:36677856-36677857:+		[2]
Sequence	ATGTGGGGAGTATTCAGGAGACAGACAACTCACTCGTCAAA
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000448526.6; ENST00000459970.1; ENST00000615513.4
External Link	RMBase: m6A_site_715134
mod ID: M6ASITE074868		Click to Show/Hide the Full List
mod site	chr6:36678816-36678817:+		[2]
Sequence	AGGTGAGAGAGCGGCGGCAGACAACAGGGGACCCCGGGCCG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; A549; MT4; CD4T; peripheral-blood; GSC-11; HEK293T; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000478800.1; ENST00000459970.1; ENST00000615513.4; ENST00000373711.3; ENST00000405375.5; ENST00000462537.3; ENST00000448526.6; ENST00000244741.9
External Link	RMBase: m6A_site_715135
mod ID: M6ASITE074869		Click to Show/Hide the Full List
mod site	chr6:36678826-36678827:+		[2]
Sequence	GCGGCGGCAGACAACAGGGGACCCCGGGCCGGCGGCCCAGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; A549; MT4; CD4T; peripheral-blood; GSC-11; HEK293T; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000615513.4; ENST00000478800.1; ENST00000373711.3; ENST00000459970.1; ENST00000462537.3; ENST00000405375.5; ENST00000448526.6; ENST00000244741.9
External Link	RMBase: m6A_site_715136
mod ID: M6ASITE074870		Click to Show/Hide the Full List
mod site	chr6:36680530-36680531:+		[2]
Sequence	CGAGCAGCGCCTTGCAGGAAACTGACTCATCACTACTCCCT
Motif Score	2.627720238
Cell/Tissue List	HeLa; GSC-11
Seq Type List	m6A-seq
Transcript ID List	ENST00000615513.4; ENST00000405375.5; ENST00000244741.9; ENST00000459970.1; ENST00000462537.3; ENST00000373711.3; ENST00000448526.6; ENST00000478800.1
External Link	RMBase: m6A_site_715137
mod ID: M6ASITE074871		Click to Show/Hide the Full List
mod site	chr6:36684109-36684110:+		[2]
Sequence	GCTGCAGGCGCCATGTCAGAACCGGCTGGGGATGTCCGTCA
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; MT4; A549; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000615513.4; ENST00000459970.1; ENST00000448526.6; ENST00000405375.5; ENST00000373711.3; ENST00000244741.9; ENST00000478800.1
External Link	RMBase: m6A_site_715138
mod ID: M6ASITE074872		Click to Show/Hide the Full List
mod site	chr6:36684132-36684133:+		[2]
Sequence	GGCTGGGGATGTCCGTCAGAACCCATGCGGCAGCAAGGCCT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; MT4; A549; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000373711.3; ENST00000478800.1; ENST00000459970.1; ENST00000615513.4; ENST00000448526.6; ENST00000405375.5; ENST00000244741.9
External Link	RMBase: m6A_site_715139
mod ID: M6ASITE074873		Click to Show/Hide the Full List
mod site	chr6:36684177-36684178:+		[2]
Sequence	CCGCCTCTTCGGCCCAGTGGACAGCGAGCAGCTGAGCCGCG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; MT4; A549; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000244741.9; ENST00000373711.3; ENST00000459970.1; ENST00000478800.1; ENST00000615513.4; ENST00000405375.5; ENST00000448526.6
External Link	RMBase: m6A_site_715140
mod ID: M6ASITE074874		Click to Show/Hide the Full List
mod site	chr6:36684249-36684250:+		[2]
Sequence	GGAGGCCCGTGAGCGATGGAACTTCGACTTTGTCACCGAGA
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; MT4; A549; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000244741.9; ENST00000615513.4; ENST00000405375.5; ENST00000459970.1; ENST00000478800.1; ENST00000448526.6; ENST00000373711.3
External Link	RMBase: m6A_site_715141
mod ID: M6ASITE074875		Click to Show/Hide the Full List
mod site	chr6:36684269-36684270:+		[2]
Sequence	ACTTCGACTTTGTCACCGAGACACCACTGGAGGGTGACTTC
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; hESC-HEK293T; MT4; A549; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000478800.1; ENST00000448526.6; ENST00000615513.4; ENST00000459970.1; ENST00000405375.5; ENST00000373711.3; ENST00000244741.9
External Link	RMBase: m6A_site_715142
mod ID: M6ASITE074876		Click to Show/Hide the Full List
mod site	chr6:36684285-36684286:+		[3]
Sequence	CGAGACACCACTGGAGGGTGACTTCGCCTGGGAGCGTGTGC
Motif Score	3.28175
Cell/Tissue List	AML
Seq Type List	miCLIP
Transcript ID List	ENST00000615513.4; ENST00000478800.1; ENST00000373711.3; ENST00000459970.1; ENST00000448526.6; ENST00000405375.5; ENST00000244741.9
External Link	RMBase: m6A_site_715143
mod ID: M6ASITE074877		Click to Show/Hide the Full List
mod site	chr6:36684413-36684414:+		[2]
Sequence	CACCTGCTCTGCTGCAGGGGACAGCAGAGGAAGACCATGTG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; H1A; H1B; A549; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; HEK293A-TOA; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000405375.5; ENST00000373711.3; ENST00000615513.4; ENST00000459970.1; ENST00000448526.6; ENST00000244741.9; ENST00000478800.1
External Link	RMBase: m6A_site_715144
mod ID: M6ASITE074878		Click to Show/Hide the Full List
mod site	chr6:36684426-36684427:+		[2]
Sequence	GCAGGGGACAGCAGAGGAAGACCATGTGGACCTGTCACTGT
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; H1A; H1B; A549; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; HEK293A-TOA; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448526.6; ENST00000405375.5; ENST00000478800.1; ENST00000244741.9; ENST00000615513.4; ENST00000373711.3; ENST00000459970.1
External Link	RMBase: m6A_site_715145
mod ID: M6ASITE074879		Click to Show/Hide the Full List
mod site	chr6:36684435-36684436:+		[2]
Sequence	AGCAGAGGAAGACCATGTGGACCTGTCACTGTCTTGTACCC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; H1A; H1B; A549; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; HEK293A-TOA; TIME; endometrial; HEC-1-A; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000373711.3; ENST00000244741.9; ENST00000615513.4; ENST00000478800.1; ENST00000459970.1; ENST00000405375.5; ENST00000448526.6
External Link	RMBase: m6A_site_715146
mod ID: M6ASITE074880		Click to Show/Hide the Full List
mod site	chr6:36684499-36684500:+		[2]
Sequence	GCTGAAGGGTCCCCAGGTGGACCTGGAGACTCTCAGGGTCG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; H1A; H1B; A549; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; TIME; endometrial; HEC-1-A; NB4; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000244741.9; ENST00000459970.1; ENST00000405375.5; ENST00000373711.3; ENST00000615513.4; ENST00000448526.6
External Link	RMBase: m6A_site_715147
mod ID: M6ASITE074881		Click to Show/Hide the Full List
mod site	chr6:36684507-36684508:+		[2]
Sequence	GTCCCCAGGTGGACCTGGAGACTCTCAGGGTCGAAAACGGC
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; H1A; H1B; A549; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; TIME; endometrial; HEC-1-A; NB4; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000615513.4; ENST00000448526.6; ENST00000405375.5; ENST00000459970.1; ENST00000373711.3; ENST00000244741.9
External Link	RMBase: m6A_site_715148
mod ID: M6ASITE074882		Click to Show/Hide the Full List
mod site	chr6:36684533-36684534:+		[2]
Sequence	AGGGTCGAAAACGGCGGCAGACCAGCATGACAGGTGCGGAC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; H1A; A549; CD4T; peripheral-blood; GSC-11; HEK293T; TIME; endometrial; HEC-1-A; NB4; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000405375.5; ENST00000448526.6; ENST00000244741.9; ENST00000373711.3; ENST00000615513.4
External Link	RMBase: m6A_site_715149
mod ID: M6ASITE074883		Click to Show/Hide the Full List
mod site	chr6:36685856-36685857:+		[4]
Sequence	GGGCCTCAAAGGCCCGCTCTACATCTTCTGCCTTAGTCTCA
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000615513.4; ENST00000244741.9; ENST00000405375.5; ENST00000373711.3; ENST00000448526.6
External Link	RMBase: m6A_site_715150
mod ID: M6ASITE074884		Click to Show/Hide the Full List
mod site	chr6:36685915-36685916:+		[5]
Sequence	TTATTTGTGTTTTAATTTAAACACCTCCTCATGTACATACC
Motif Score	2.20572619
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000405375.5; ENST00000448526.6; ENST00000615513.4; ENST00000373711.3; ENST00000244741.9
External Link	RMBase: m6A_site_715151
mod ID: M6ASITE074885		Click to Show/Hide the Full List
mod site	chr6:36685929-36685930:+		[5]
Sequence	ATTTAAACACCTCCTCATGTACATACCCTGGCCGCCCCCTG
Motif Score	2.856142857
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000615513.4; ENST00000448526.6; ENST00000244741.9; ENST00000405375.5
External Link	RMBase: m6A_site_715152
mod ID: M6ASITE074886		Click to Show/Hide the Full List
mod site	chr6:36685981-36685982:+		[2]
Sequence	CTGGCATTAGAATTATTTAAACAAAAACTAGGCGGTTGAAT
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T
Seq Type List	m6A-seq; DART-seq; MAZTER-seq
Transcript ID List	ENST00000244741.9; ENST00000405375.5; ENST00000615513.4; ENST00000448526.6
External Link	RMBase: m6A_site_715153
mod ID: M6ASITE074887		Click to Show/Hide the Full List
mod site	chr6:36685987-36685988:+		[2]
Sequence	TTAGAATTATTTAAACAAAAACTAGGCGGTTGAATGAGAGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000405375.5; ENST00000448526.6; ENST00000615513.4; ENST00000244741.9
External Link	RMBase: m6A_site_715154
mod ID: M6ASITE074888		Click to Show/Hide the Full List
mod site	chr6:36686044-36686045:+		[5]
Sequence	GCATTTTTATTTTATGAAATACTATTTAAAGCCTCCTCATC
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000448526.6; ENST00000244741.9; ENST00000405375.5; ENST00000615513.4
External Link	RMBase: m6A_site_715155
mod ID: M6ASITE074889		Click to Show/Hide the Full List
mod site	chr6:36686153-36686154:+		[5]
Sequence	CCACTTGTCCGCTGGGTGGTACCCTCTGGAGGGGTGTGGCT
Motif Score	2.8355
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000615513.4; ENST00000244741.9; ENST00000405375.5; ENST00000448526.6
External Link	RMBase: m6A_site_715156
mod ID: M6ASITE074890		Click to Show/Hide the Full List
mod site	chr6:36686190-36686191:+		[5]
Sequence	GGCTCCTTCCCATCGCTGTCACAGGCGGTTATGAAATTCAC
Motif Score	2.047297619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000244741.9; ENST00000615513.4; ENST00000448526.6; ENST00000405375.5
External Link	RMBase: m6A_site_715157
mod ID: M6ASITE074891		Click to Show/Hide the Full List
mod site	chr6:36686260-36686261:+		[5]
Sequence	CTTTTTCATTTGAGAAGTAAACAGATGGCACTTTGAAGGGG
Motif Score	2.20572619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000244741.9; ENST00000615513.4; ENST00000405375.5; ENST00000448526.6
External Link	RMBase: m6A_site_715158
mod ID: M6ASITE074892		Click to Show/Hide the Full List
mod site	chr6:36686269-36686270:+		[5]
Sequence	TTGAGAAGTAAACAGATGGCACTTTGAAGGGGCCTCACCGA
Motif Score	3.252583333
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000244741.9; ENST00000615513.4; ENST00000405375.5; ENST00000448526.6
External Link	RMBase: m6A_site_715159
mod ID: M6ASITE074893		Click to Show/Hide the Full List
mod site	chr6:36686308-36686309:+		[2]
Sequence	GAGTGGGGGCATCATCAAAAACTTTGGAGTCCCCTCACCTC
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000615513.4; ENST00000448526.6; ENST00000405375.5; ENST00000244741.9
External Link	RMBase: m6A_site_715160
mod ID: M6ASITE074894		Click to Show/Hide the Full List
mod site	chr6:36686385-36686386:+		[2]
Sequence	AGCCTAGGGCTGAGCTGGGGACCTGGTACCCTCCTGGCTCT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000448526.6; ENST00000405375.5; ENST00000244741.9; ENST00000615513.4
External Link	RMBase: m6A_site_715161
mod ID: M6ASITE074895		Click to Show/Hide the Full List
mod site	chr6:36686459-36686460:+		[2]
Sequence	AAGGTGGGGTCCTGGAGCAGACCACCCCGCCTGCCCTCATG
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000405375.5; ENST00000244741.9; ENST00000615513.4; ENST00000448526.6
External Link	RMBase: m6A_site_715162
mod ID: M6ASITE074896		Click to Show/Hide the Full List
mod site	chr6:36686699-36686700:+		[6]
Sequence	CCCCACCCCCAGCTCAATGGACTGGAAGGGGAAGGGACACA
Motif Score	4.065041667
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000405375.5; ENST00000615513.4; ENST00000448526.6; ENST00000244741.9
External Link	RMBase: m6A_site_715163
mod ID: M6ASITE074897		Click to Show/Hide the Full List
mod site	chr6:36686715-36686716:+		[6]
Sequence	ATGGACTGGAAGGGGAAGGGACACACAAGAAGAAGGGCACC
Motif Score	3.643047619
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000244741.9; ENST00000615513.4; ENST00000405375.5; ENST00000448526.6
External Link	RMBase: m6A_site_715164
mod ID: M6ASITE074898		Click to Show/Hide the Full List
mod site	chr6:36686719-36686720:+		[4]
Sequence	ACTGGAAGGGGAAGGGACACACAAGAAGAAGGGCACCCTAG
Motif Score	2.084928571
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000448526.6; ENST00000244741.9; ENST00000615513.4; ENST00000405375.5
External Link	RMBase: m6A_site_715165
mod ID: M6ASITE074899		Click to Show/Hide the Full List
mod site	chr6:36686885-36686886:+		[5]
Sequence	TAGATCTTTCTAGGAGGGAGACACTGGCCCCTCAAATCGTC
Motif Score	2.897386905
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000405375.5; ENST00000244741.9; ENST00000448526.6; ENST00000615513.4
External Link	RMBase: m6A_site_715166
mod ID: M6ASITE074900		Click to Show/Hide the Full List
mod site	chr6:36686949-36686950:+		[5]
Sequence	ATCCCTCCCCAGTTCATTGCACTTTGATTAGCAGCGGAACA
Motif Score	3.252583333
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000244741.9; ENST00000615513.4; ENST00000448526.6; ENST00000405375.5
External Link	RMBase: m6A_site_715167
mod ID: M6ASITE074901		Click to Show/Hide the Full List
mod site	chr6:36686967-36686968:+		[4]
Sequence	GCACTTTGATTAGCAGCGGAACAAGGAGTCAGACATTTTAA
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000615513.4; ENST00000405375.5; ENST00000448526.6; ENST00000244741.9
External Link	RMBase: m6A_site_715168
mod ID: M6ASITE074902		Click to Show/Hide the Full List
mod site	chr6:36687132-36687133:+		[4]
Sequence	GTATTGGGGTCTGACCCCAAACACCTTCCAGCTCCTGTAAC
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T; HeLa; peripheral-blood
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	ENST00000405375.5; ENST00000244741.9; ENST00000448526.6; ENST00000615513.4
External Link	RMBase: m6A_site_715169
mod ID: M6ASITE074903		Click to Show/Hide the Full List
mod site	chr6:36687151-36687152:+		[4]
Sequence	AACACCTTCCAGCTCCTGTAACATACTGGCCTGGACTGTTT
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000244741.9; ENST00000405375.5; ENST00000448526.6; ENST00000615513.4
External Link	RMBase: m6A_site_715170
mod ID: M6ASITE074904		Click to Show/Hide the Full List
mod site	chr6:36687165-36687166:+		[7]
Sequence	CCTGTAACATACTGGCCTGGACTGTTTTCTCTCGGCTCCCC
Motif Score	4.065041667
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000615513.4; ENST00000405375.5; ENST00000448526.6; ENST00000244741.9
External Link	RMBase: m6A_site_715171
mod ID: M6ASITE074905		Click to Show/Hide the Full List
mod site	chr6:36687216-36687217:+		[7]
Sequence	GTTCCCGTTTCTCCACCTAGACTGTAAACCTCTCGAGGGCA
Motif Score	3.319380952
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000244741.9; rmsk_1919675; ENST00000448526.6; ENST00000615513.4; ENST00000405375.5
External Link	RMBase: m6A_site_715172
mod ID: M6ASITE074906		Click to Show/Hide the Full List
mod site	chr6:36687223-36687224:+		[2]
Sequence	TTTCTCCACCTAGACTGTAAACCTCTCGAGGGCAGGGACCA
Motif Score	2.185083333
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000448526.6; rmsk_1919675; ENST00000615513.4; ENST00000405375.5; ENST00000244741.9
External Link	RMBase: m6A_site_715173
mod ID: M6ASITE074907		Click to Show/Hide the Full List
mod site	chr6:36687240-36687241:+		[2]
Sequence	TAAACCTCTCGAGGGCAGGGACCACACCCTGTACTGTTCTG
Motif Score	3.622404762
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000615513.4; ENST00000405375.5; ENST00000448526.6; ENST00000244741.9; rmsk_1919675
External Link	RMBase: m6A_site_715174
mod ID: M6ASITE074908		Click to Show/Hide the Full List
mod site	chr6:36687243-36687244:+		[4]
Sequence	ACCTCTCGAGGGCAGGGACCACACCCTGTACTGTTCTGTGT
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	rmsk_1919675; ENST00000405375.5; ENST00000615513.4; ENST00000244741.9; ENST00000448526.6
External Link	RMBase: m6A_site_715175

Ref 1	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 2	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 3	The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nat Med. 2017 Nov;23(11):1369-1376. doi: 10.1038/nm.4416. Epub 2017 Sep 18.
Ref 4	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 5	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 6	Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells. Nat Microbiol. 2016 Feb 22;1:16011. doi: 10.1038/nmicrobiol.2016.11.
Ref 7	N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505(7481):117-20. doi: 10.1038/nature12730. Epub 2013 Nov 27.

Epigenetic Target Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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