Epigenetic Regulator Information

General Information of the Epigenetic Regulator (ID: EPIREG00076)
Regulator Name Chromobox protein homolog 1 (CBX1)
Gene Name CBX1
Sequence
MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN
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Function
Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
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Gene ID 10951
Uniprot ID
CBX1_HUMAN
Epigenetic Regulation Type Histone modification (Methylation)
Regulator Type WRITER ERASER READER