m6A-centered Drug Response Information
General Information of the Drug (ID: M6APDG02393)
Name |
Arsenic
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Synonyms |
Agent SA; Arsen [German,Polish]; Arsenic; Arsenic Black; Arsenic Lump (Metals Basis); Arsenic and arsenic compounds; Arsenic compounds; Arsenic hydride (AsH3); Arsenic, elemental; Arsenic, inorganic; Arsenic, organic compounds; Arsenic-75; Arsenicals; Arsenowodor [Polish]; Arsenwasserstoff [German]; Colloidal arsenic; Gray arsenic; Grey arsenic; Metallic arsenic; UN 2188; UN1558; UN2188; V1I29R0RJQ; 7440-38-2; Arsen; As; CCRIS 55; EINECS 231-148-6; EINECS 232-066-3; HSDB 509; HSDB 510; N712M78A8G; UNII-N712M78A8G; UNII-V1I29R0RJQ
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Status |
Approved
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Structure |
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3D MOL
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Formula |
As
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InChI |
1S/As
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InChIKey |
RQNWIZPPADIBDY-UHFFFAOYSA-N
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PubChem CID | |||||
INTEDE Drug ID |
Target Gene(s) and Their Upstream m6A Regulator, Together with the Effect of Target Gene(s) in Drug Response
The target genes involved in drug-target interaction (such as drug-metabolizing enzymes, drug transporters and therapeutic targets) and drug-mediated cell death signaling (including modulating DNA damage and repair capacity, escaping from drug-induced apoptosis, autophagy, cellular metabolic reprogramming, oncogenic bypass signaling, cell microenvironment, cell stemness, etc.) could be regulated by m6A regulator(s) and affected their corresponding drug response. You can browse detailed information on drug-related target gene(s) mediated by m6A regulators.
Serine sulfhydrase (CBS)
YTH domain-containing family protein 2 (YTHDF2)
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Serine sulfhydrase (CBS) is a therapeutic target for Arsenic. The YTH domain-containing family protein 2 (YTHDF2) has potential in affecting the response of Arsenic through regulating the expression of Serine sulfhydrase (CBS). | [1], [2] | ||
References