m6A-centered Drug Response Information
General Information of the Drug (ID: M6ADRUG0143)
| Name |
ICARIIN
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| Synonyms |
489-32-7; Ieariline; UNII-VNM47R2QSQ; CHEBI:78420; VNM47R2QSQ; Icariine; 3-((6-Deoxymannopyranosyl)oxy)-7-(glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one; Icarin; 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-7-(be
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| Structure |
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3D MOL
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| Formula |
C33H40O15
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| InChI |
1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
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| InChIKey |
TZJALUIVHRYQQB-XLRXWWTNSA-N
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Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Drug
| In total 1 item(s) under this drug | ||
| Crosstalk ID: M6ACROT05153 | ||
| m6A Regulator | Methyltransferase-like 14 (METTL14) | |
| m6A Target | Protein disulfide-isomerase (P4HB) | |
| Epigenetic Regulator | hsa-miR-103-3p | |
| Regulated Target | Methyltransferase-like protein 14 (METTL14) | |
| Crosstalk relationship | ncRNA → m6A | |
| Disease | Osteoporosis | |