Regulator ID target symbol target name hgnc_id ensembl_gene_id uniprot ID Entrez_id type type_class cell_line cell_id species cell_disease ICD_disease method PMID GSE log2FoldChange perturbation direction pvalue REG00007 LRTOMT leucine rich transmembrane and O-methyltransferase domain containing HGNC:25033 ENSG00000284922 . 220074 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 1.00E+00 . . . REG00007 GCOM1 GCOM1, MYZAP-POLR2M combined locus HGNC:26424 ENSG00000137878 . 145781 Readthrough Other Caco-2 CVCL_0025 Homo sapiens Colorectal adenocarcinoma 2B91: Colorectal cancer RNA-seq 33961823 GSE167075 -0.657219826 knock down down-regulator 0.003081945 REG00007 GCOM1 GCOM1, MYZAP-POLR2M combined locus HGNC:26424 ENSG00000137878 . 145781 Readthrough Other HeLa cell line CVCL_0030 Homo sapiens Cervical cancer 2C77: Cervical cancer RNA-seq 26321680 GSE70061 1.436105134 knock down up-regulate 2.12E-24 REG00007 STON1-GTF2A1L STON1-GTF2A1L readthrough HGNC:30651 ENSG00000068781 . 286749 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.03E+00 . . . REG00007 PPAN-P2RY11 PPAN-P2RY11 readthrough HGNC:33526 ENSG00000243207 . 692312 Readthrough Other LX2 . Homo sapiens Healthy . RNA-seq . GSE207909 -0.6138 knock down down-regulator 0.004438 REG00007 ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough HGNC:33530 ENSG00000254996 . 404734 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 1.84E+00 . . . REG00007 ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough HGNC:33530 ENSG00000254996 . 404734 Readthrough Other HULEC-5a CVCL_0A11 Homo sapiens Healthy . RNA-seq . GSE200649 -2.353049209 knock down down-regulator 0.000257429 REG00007 ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough HGNC:33530 ENSG00000254996 . 404734 Readthrough Other LX2 . Homo sapiens Healthy . RNA-seq . GSE207909 -1.261240439 knock down down-regulator 0.005597352 REG00007 NME1-NME2 NME1-NME2 readthrough HGNC:33531 ENSG00000011052 . 654364 Readthrough Other LX2 . Homo sapiens Healthy . RNA-seq . GSE207909 0.663584083 knock down up-regulate 0.004821097 REG00007 TMED7-TICAM2 TMED7-TICAM2 readthrough HGNC:33945 ENSG00000251201 . 100302736 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RNA-seq 26321680 GSE70061 -2.952409876 knock down down-regulator 4.63E-06 REG00007 JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough HGNC:34449 ENSG00000168970 . 8681 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 1.56E+00 . . . REG00007 JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough HGNC:34449 ENSG00000168970 . 8681 Readthrough Other ARPE-19 CVCL_0145 Homo sapiens Healthy . RNA-seq 35936005 GSE202017 0.889697781 knock down up-regulate 0.000103382 REG00007 JMJD7-PLA2G4B JMJD7-PLA2G4B readthrough HGNC:34449 ENSG00000168970 . 8681 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RNA-seq 26321680 GSE70061 -1.047346768 knock down down-regulator 1.01E-06 REG00007 PRR5-ARHGAP8 PRR5-ARHGAP8 readthrough HGNC:34512 ENSG00000248405 . 553158 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 4.52E+00 . . . REG00007 DNAJC25-GNG10 DNAJC25-GNG10 readthrough HGNC:37501 ENSG00000244115 . 552891 Readthrough Other Caco-2 CVCL_0025 Homo sapiens Colorectal adenocarcinoma 2B91: Colorectal cancer RNA-seq 33961823 GSE167075 1.510334072 knock down up-regulate 0.030202242 REG00007 C15orf38-AP3S2 ARPIN-AP3S2 readthrough HGNC:38824 ENSG00000250021 . 100526783 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.85E+00 . . . REG00007 TMEM110-MUSTN1 STIMATE-MUSTN1 readthrough HGNC:38834 ENSG00000248592 . 100526772 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 1.03E+00 . . . REG00007 RBM14-RBM4 RBM14-RBM4 readthrough HGNC:38840 ENSG00000248643 . 100526737 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 9.22E+00 . . . REG00007 RBM14-RBM4 RBM14-RBM4 readthrough HGNC:38840 ENSG00000248643 . 100526737 Readthrough Other LX2 . Homo sapiens Healthy . RNA-seq . GSE207909 -1.017578645 knock down down-regulator 0.008537666 REG00007 RBM14-RBM4 RBM14-RBM4 readthrough HGNC:38840 ENSG00000248643 . 100526737 Readthrough Other HeLa cell line CVCL_0030 Homo sapiens Cervical cancer 2C77: Cervical cancer RNA-seq 26321680 GSE70061 -0.845017958 knock down down-regulator 0.012395247 REG00007 IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough HGNC:38842 ENSG00000283154 IQIP1_HUMAN 100505385 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RNA-seq 26321680 GSE70061 0.755706476 knock down up-regulate 0.00084868 REG00007 APITD1-CORT CENPS-CORT readthrough HGNC:38843 ENSG00000251503 . 100526739 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.01E+00 . . . REG00007 ABHD14A-ACY1 ABHD14A-ACY1 readthrough HGNC:38856 ENSG00000114786 . 100526760 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.14E+00 . . . REG00007 NEDD8-MDP1 NEDD8-MDP1 readthrough HGNC:39551 ENSG00000255526 . 100528064 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 1.13E+01 . . . REG00007 BORCS8-MEF2B BORCS8-MEF2B readthrough HGNC:39979 ENSG00000064489 . 4207 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.92E+00 . . . REG00007 STX16-NPEPL1 STX16-NPEPL1 readthrough (NMD candidate) HGNC:41993 ENSG00000254995 . 100534593 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 8.14E+00 . . . REG00007 MSH5-SAPCD1 MSH5-SAPCD1 readthrough (NMD candidate) HGNC:41994 ENSG00000255152 . 100532732 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 8.34E+00 . . . REG00007 INMT-MINDY4 INMT-MINDY4 readthrough (NMD candidate) HGNC:41995 ENSG00000254959 . 100526825 Readthrough Other HeLa cell line CVCL_0030 Homo sapiens Cervical cancer 2C77: Cervical cancer RNA-seq 26321680 GSE70061 0.669143738 knock down up-regulate 8.93E-05 REG00007 CHKB-CPT1B CHKB-CPT1B readthrough (NMD candidate) HGNC:41998 ENSG00000254413 . 386593 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 1.05E+01 . . . REG00007 ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough HGNC:42000 ENSG00000271147 . 100528062 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 8.26E+00 . . . REG00007 ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough HGNC:42000 ENSG00000271147 . 100528062 Readthrough Other LNCaP CVCL_0395 Homo sapiens Prostate carcinoma 2C82: Prostate cancer RNA-seq 34321211 GSE147884 0.850256354 knock down up-regulate 0.017339762 REG00007 ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough HGNC:42000 ENSG00000271147 . 100528062 Readthrough Other Caco-2 CVCL_0025 Homo sapiens Colorectal adenocarcinoma 2B91: Colorectal cancer RNA-seq 33961823 GSE167075 3.973931546 knock down up-regulate 0.0428907 REG00007 BLOC1S5-TXNDC5 BLOC1S5-TXNDC5 readthrough (NMD candidate) HGNC:42001 ENSG00000259040 . 100526836 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.16E+00 . . . REG00007 BLOC1S5-TXNDC5 BLOC1S5-TXNDC5 readthrough (NMD candidate) HGNC:42001 ENSG00000259040 . 100526836 Readthrough Other HeLa cell line CVCL_0030 Homo sapiens Cervical cancer 2C77: Cervical cancer RNA-seq 26321680 GSE70061 -1.947016887 knock down down-regulator 0.012155 REG00007 FPGT-TNNI3K FPGT-TNNI3K readthrough HGNC:42952 ENSG00000259030 . 100526835 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 4.67E+00 . . . REG00007 FPGT-TNNI3K FPGT-TNNI3K readthrough HGNC:42952 ENSG00000259030 . 100526835 Readthrough Other ARPE-19 CVCL_0145 Homo sapiens Healthy . RNA-seq 35936005 GSE202017 -0.915069312 knock down down-regulator 0.00042853 REG00007 NDUFC2-KCTD14 NDUFC2-KCTD14 readthrough HGNC:42956 ENSG00000259112 NDUCR_HUMAN 100532726 Readthrough Other Caco-2 CVCL_0025 Homo sapiens Colorectal adenocarcinoma 2B91: Colorectal cancer RNA-seq 33961823 GSE167075 0.677838272 knock down up-regulate 0.003579338 REG00007 BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough HGNC:42959 ENSG00000258643 B2CL2_HUMAN 100529063 Readthrough Other LX2 . Homo sapiens Healthy . RNA-seq . GSE207909 -1.118540434 knock down down-regulator 0.026442777 REG00007 TVP23C-CDRT4 TVP23C-CDRT4 readthrough HGNC:42961 ENSG00000259024 . 100533496 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 9.10E+00 . . . REG00007 TVP23C-CDRT4 TVP23C-CDRT4 readthrough HGNC:42961 ENSG00000259024 . 100533496 Readthrough Other LX2 . Homo sapiens Healthy . RNA-seq . GSE207909 -1.332543575 knock down down-regulator 0.000108297 REG00007 TVP23C-CDRT4 TVP23C-CDRT4 readthrough HGNC:42961 ENSG00000259024 . 100533496 Readthrough Other HeLa cell line CVCL_0030 Homo sapiens Cervical cancer 2C77: Cervical cancer RNA-seq 26321680 GSE70061 -1.279041254 knock down down-regulator 0.009524753 REG00007 ISY1-RAB43 ISY1-RAB43 readthrough HGNC:42969 ENSG00000261796 . 100534599 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.00E+00 . . . REG00007 ISY1-RAB43 ISY1-RAB43 readthrough HGNC:42969 ENSG00000261796 . 100534599 Readthrough Other LX2 . Homo sapiens Healthy . RNA-seq . GSE207909 1.345799103 knock down up-regulate 0.000680953 REG00007 RBAK-RBAKDN RBAK-RBAKDN readthrough HGNC:42971 ENSG00000272968 . 100533952 Readthrough Other HeLa cell line CVCL_0030 Homo sapiens Cervical cancer 2C77: Cervical cancer RNA-seq 26321680 GSE70061 -0.892859359 knock down down-regulator 0.038650176 REG00007 DNAAF4-CCPG1 DNAAF4-CCPG1 readthrough (NMD candidate) HGNC:43019 ENSG00000261771 . 100533483 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RNA-seq 26321680 GSE70061 0.983835356 knock down up-regulate 0.005351236 REG00007 BIVM-ERCC5 BIVM-ERCC5 readthrough HGNC:43690 ENSG00000270181 . 100533467 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.05E+00 . . . REG00007 BIVM-ERCC5 BIVM-ERCC5 readthrough HGNC:43690 ENSG00000270181 . 100533467 Readthrough Other LX2 . Homo sapiens Healthy . RNA-seq . GSE207909 -0.961390644 knock down down-regulator 0.034812631 REG00007 PTGES3L-AARSD1 PTGES3L-AARSD1 readthrough HGNC:43946 ENSG00000108825 AASD1_HUMAN 100885850 Readthrough Other LX2 . Homo sapiens Healthy . RNA-seq . GSE207909 -0.921136565 knock down down-regulator 0.019585291 REG00007 RTEL1-TNFRSF6B RTEL1-TNFRSF6B readthrough (NMD candidate) HGNC:44095 ENSG00000026036 . 100533107 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 1.44E+00 . . . REG00007 RNASEK-C17orf49 RNASEK-C17orf49 readthrough HGNC:44419 ENSG00000161939 . 100529209 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 9.54E+00 . . . REG00007 RNASEK-C17orf49 RNASEK-C17orf49 readthrough HGNC:44419 ENSG00000161939 . 100529209 Readthrough Other HeLa cell line CVCL_0030 Homo sapiens Cervical cancer 2C77: Cervical cancer RNA-seq 26321680 GSE70061 1.506464303 knock down up-regulate 0.000410884 REG00007 SLX1A-SULT1A3 SLX1A-SULT1A3 readthrough (NMD candidate) HGNC:44437 ENSG00000213599 . 100526830 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 8.68E+00 . . . REG00007 RAB4B-EGLN2 RAB4B-EGLN2 readthrough (NMD candidate) HGNC:44465 ENSG00000171570 . 100529264 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 8.23E+00 . . . REG00007 TGIF2-C20orf24 TGIF2-RAB5IF readthrough HGNC:44664 ENSG00000259399 . 100527943 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.42E+00 . . . REG00007 LINC00843 TIMM23B-AGAP6 readthrough (NMD candidate) HGNC:45009 ENSG00000178440 . 113218477 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 1.01E+01 . . . REG00007 COMMD3-BMI1 COMMD3-BMI1 readthrough HGNC:48326 ENSG00000269897 . 100532731 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.83E+00 . . . REG00007 MINOS1-NBL1 MICOS10-NBL1 readthrough HGNC:48338 ENSG00000270136 . 100532736 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 5.32E+00 . . . REG00007 PPT2-EGFL8 PPT2-EGFL8 readthrough (NMD candidate) HGNC:48343 ENSG00000258388 . 100532746 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 2.79E+00 . . . REG00007 ARHGAP19-SLIT1 ARHGAP19-SLIT1 readthrough (NMD candidate) HGNC:48348 ENSG00000269891 . 100533184 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 5.02E+00 . . . REG00007 NPHP3-ACAD11 NPHP3-ACAD11 readthrough (NMD candidate) HGNC:48351 ENSG00000274810 . 100532724 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.95E+00 . . . REG00007 SLX1B-SULT1A4 SLX1B-SULT1A4 readthrough (NMD candidate) HGNC:48353 ENSG00000260280 . 100526831 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.29E+00 . . . REG00007 KLRC4-KLRK1 KLRC4-KLRK1 readthrough HGNC:48357 ENSG00000255819 . 100528032 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 8.67E+00 . . . REG00007 STAG3L5P-PVRIG2P-PILRB STAG3L5P-PVRIG2P-PILRB readthrough HGNC:48898 ENSG00000272752 . 101752399 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 8.16E+00 . . . REG00007 RPS10-NUDT3 RPS10-NUDT3 readthrough HGNC:49181 ENSG00000270800 . 100529239 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 2.42E+00 . . . REG00007 RPS10-NUDT3 RPS10-NUDT3 readthrough HGNC:49181 ENSG00000270800 . 100529239 Readthrough Other HeLa cell line CVCL_0030 Homo sapiens Cervical cancer 2C77: Cervical cancer RNA-seq 26321680 GSE70061 0.916752274 knock down up-regulate 0.000164347 REG00007 RPS10-NUDT3 RPS10-NUDT3 readthrough HGNC:49181 ENSG00000270800 . 100529239 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RNA-seq 26321680 GSE70061 0.668960451 knock down up-regulate 0.00638175 REG00007 SENP3-EIF4A1 SENP3-EIF4A1 readthrough (NMD candidate) HGNC:49182 ENSG00000277957 . 100533955 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 7.45E+00 . . . REG00007 URGCP-MRPS24 URGCP-MRPS24 readthrough HGNC:49188 ENSG00000270617 . 100534592 Readthrough Other LX2 . Homo sapiens Healthy . RNA-seq . GSE207909 1.837765875 knock down up-regulate 0.001417132 REG00007 HNRNPUL2-BSCL2 HNRNPUL2-BSCL2 readthrough (NMD candidate) HGNC:49189 ENSG00000234857 . 100534595 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 6.69E+00 . . . REG00007 ZNF670-ZNF695 ZNF670-ZNF695 readthrough (NMD candidate) HGNC:49200 ENSG00000135747 . 100533111 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 6.42E+00 . . . REG00007 TMEM56-RWDD3 TLCD4-RWDD3 readthrough HGNC:49388 ENSG00000271092 . 100527978 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 4.43E+00 . . . REG00007 CYP3A7-CYP3A51P CYP3A7-CYP3A51P readthrough HGNC:51504 ENSG00000282301 . 100861540 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 6.36E+00 . . . REG00007 RP11-23J9.4 SUGT1P4-STRA6LP-CCDC180 readthrough HGNC:53835 ENSG00000255036 . 57653 Readthrough Other MDA-MB-231 CVCL_0062 Homo sapiens Breast cancer 2C60: Breast cancer RIP-seq 25799998 GSE60213 6.52E+00 . . . REG00007 SUGT1P4-STRA6LP-CCDC180 SUGT1P4-STRA6LP-CCDC180 readthrough HGNC:53835 ENSG00000255036 . 57653 Readthrough Other HeLa cell line CVCL_0030 Homo sapiens Cervical cancer 2C77: Cervical cancer RNA-seq 26321680 GSE70061 0.847641817 knock down up-regulate 0.011283007